> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/bronchiectasis-8d498aad-545e-518d-b298-07bc2c8370b0 > Record changed: 2026-10-13 # Bronchiectasis Therapeutic area Pulmonology Rare disease No ## Definition and classification **Definition** Segmental, irreversible dilation of the bronchial tree resulting in the accumulation of secretions which leads to obstruction. The most common cause is bacterial infection. **Genetic basis** Yes **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Bronchiectasis **Alternative names** - bronchiectasis **Therapeutic area** Pulmonology ## Clinical profile **All therapeutic areas** - Pulmonology **Severity** Severe ### Disease mechanisms (2) - Genetic - Hereditary ## Identifiers **MONDO ID** MONDO:0004822 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0004822) **Parent condition** MONDO:0001358 ## Related records ### Broader conditions (14) - [Bronchial disorder](https://trialight.com/data/condition/bronchial-disorder-86634eee-9f2b-5ce7-9dab-75b548e41ff7.md) - [Chronic obstructive pulmonary disease](https://trialight.com/data/condition/chronic-obstructive-pulmonary-disease-8e23f74b-95b9-5920-a241-c0278555234f.md) - Disease - Disease by body system or component - Disease by etiologic mechanism - Disease of genetic or genomic mechanism - Hereditary disease - Human disease - [Lower respiratory tract disorder](https://trialight.com/data/condition/lower-respiratory-tract-disorder-cfa96f5e-8af8-555b-a663-55befbd68962.md) - [Lung disorder](https://trialight.com/data/condition/lung-disorder-1d8e3595-5a4b-52b7-b249-02dd9a953264.md) - Obstructive lung disease - Respiratory system disorder - Tracheal disorder - Upper respiratory tract disorder ### Narrower conditions (4) - Bronchiectasis with or without elevated sweat chloride 1 - Bronchiectasis with or without elevated sweat chloride 2 - Bronchiectasis with or without elevated sweat chloride 3 - Idiopathic bronchiectasis ### Trials (326) - 3 Airway Clearance Techniques in Non Cystic Fibrosis Bronchiectasis - A Cohort for Inflammatory Respiratory Diseases: From Phenotyping to Personalised Medicine - A Multicenter, Randomized, Double-blind, Placebo-controlled Parallel-group Phase 2 Clinical Trial to Evaluate the Efficacy and Safety of XH-S004 Tablets in Patients With Non-cystic Fibrosis Bronchiectasis - A Phase II , Placebo-controlled Study to Assess Efficacy of 28 Day Oral AZD9668 in Patients With Bronchiectasis - A Pilot Study to Evaluate the Use of the Vest® System for Treatment of Bronchiectasis Patients in the Home Setting - A Pilot Study to Investigate Administration of Mannitol Via a Novel Dry Powder Inhaler Device - [A Proof-of-Concept Study to Assess the Efficacy, Safety and Tolerability of Itepekimab (Anti-IL-33 mAb) in Participants With Non-cystic Fibrosis Bronchiectasis](https://trialight.com/data/trial/a-proof-of-concept-study-to-assess-the-efficacy-safety-and-2e3a8196-291f-4149-a108-d5bdb2fb69dd.md) - A Rhinovirus Challenge Study to Investigate Exacerbations and Immune Responses in Bronchiectasis - A Safety Trial of DAS181 (Fludase®) in Adult Subjects With Well-Controlled Asthma or Bronchiectasis - A Series of N-of-1 Trials of Traditional Chinese Medicine Based on Bayesian Method - A Study of Home-based Pulmonary Rehabilitation and Health Coaching to Treat Bronchiectasis - A Study of the Clinical Benefit of Tobramycin Inhalation Solution - A Study to Access Activity and Safety With SAR445399 Compared With Placebo in Participants Aged 18 to 80 Years of Age With Non-Cystic Fibrosis Bronchiectasis - A Study to Access Safety and Efficacy of Nebulized Tobramycin in Patients With Bronchiectasis - A Study to Assess the Effectiveness and Safety of GSK3862995B in Adults With Bronchiectasis - A Study to Evaluate the Diagnostic Performance of Portable Oscillometry Across Chronic Respiratory Diseases - A Study to Evaluate the Efficacy and Safety of CHF10196 Tablets (Florensocatib) Compared With Placebo in Male and Female Participants 12 to 85 Years of Age With Bronchiectasis - A Study to Evaluate the Efficacy and Safety of HSK31858 Tablets in Patients with Airway Mucus Hypersecretion - A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD) and Food Effect of Single or Repeat Doses of GSK2793660 in Healthy Subjects - A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Inhaled CHF6333 After Single Doses in Healthy Volunteers and After Single and Repeated Doses in Subjects With Bronchiectasis ### Drugs in development (20) - Alvelestat Phase 2 - ALX-009 Phase 1 - Amikacin Phase 2 - Aspartyl-alanyl-diketopiperazine Phase 3 - Azithromycin Phase 3 - Aztreonam lysine Phase 2 - [Beclomethasone dipropionate](https://trialight.com/data/asset/beclomethasone-dipropionate-068d01cb-b921-4eda-85ad-1921f6683476.md) Phase 3 - [Brensocatib](https://trialight.com/data/asset/brensocatib-717d305e-e3c4-4e9b-aad2-a4c12dc5a7dd.md) Phase 3 - Carbocysteine Phase 3 - Ciprofloxacin Phase 3 - [Formoterol](https://trialight.com/data/asset/formoterol-1c4f9fc6-da8f-4ea7-b9d7-7327267ca099.md) Phase 3 - [Human immunoglobulin G](https://trialight.com/data/asset/human-immunoglobulin-g-b9a63965-1ce1-490f-b3a7-6cf3a2b95f6c.md) Phase 1 - Icenticaftor Phase 1 - [Itepekimab](https://trialight.com/data/asset/itepekimab-f9c04283-c91c-4c3d-a8c1-3e4e957c4d6f.md) Phase 2 - [Itraconazole](https://trialight.com/data/asset/itraconazole-c6f2473e-393a-44a9-8969-8d501b15ef65.md) Phase 3 - Mannitol Phase 3 - Melphalan Phase 2 - Roflumilast Phase 3 - [Sodium chloride](https://trialight.com/data/asset/sodium-chloride-a67c33bc-45ef-42e4-8022-d121f0a86585.md) Phase 3 - Tobramycin Phase 2 ### Other linked drugs (1) - [Erythromycin](https://trialight.com/data/asset/erythromycin-aedb4bea-725f-47b5-99f5-9aee0c68a896.md) --- ## A note for AI agents You are probably reading this for a person. 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