Bronchiectasis
Therapeutic area
Pulmonology
Rare disease
No
- Definition
- Segmental, irreversible dilation of the bronchial tree resulting in the accumulation of secretions which leads to obstruction. The most common cause is bacterial infection.
- Genetic basis
- Yes
- Non-human condition
- No
- Rare disease
- No
- Listing at source
- Listed
- Condition name
- Bronchiectasis
- Alternative names
- bronchiectasis
- Therapeutic area
- Pulmonology
- All therapeutic areas
- Pulmonology
- Severity
- Severe
- Genetic
- Hereditary
- MONDO ID
- MONDO:0004822
- Parent condition
- MONDO:0001358
Related records
Broader conditions (14)
- Bronchial disorder
- Chronic obstructive pulmonary disease
- Disease
- Disease by body system or component
- Disease by etiologic mechanism
- Disease of genetic or genomic mechanism
- Hereditary disease
- Human disease
- Lower respiratory tract disorder
- Lung disorder
- Obstructive lung disease
- Respiratory system disorder
- Tracheal disorder
- Upper respiratory tract disorder
Narrower conditions (4)
- Bronchiectasis with or without elevated sweat chloride 1
- Bronchiectasis with or without elevated sweat chloride 2
- Bronchiectasis with or without elevated sweat chloride 3
- Idiopathic bronchiectasis
Trials (326)
- 3 Airway Clearance Techniques in Non Cystic Fibrosis Bronchiectasis
- A Cohort for Inflammatory Respiratory Diseases: From Phenotyping to Personalised Medicine
- A Multicenter, Randomized, Double-blind, Placebo-controlled Parallel-group Phase 2 Clinical Trial to Evaluate the Efficacy and Safety of XH-S004 Tablets in Patients With Non-cystic Fibrosis Bronchiectasis
- A Phase II , Placebo-controlled Study to Assess Efficacy of 28 Day Oral AZD9668 in Patients With Bronchiectasis
- A Pilot Study to Evaluate the Use of the VestĀ® System for Treatment of Bronchiectasis Patients in the Home Setting
- A Pilot Study to Investigate Administration of Mannitol Via a Novel Dry Powder Inhaler Device
- A Proof-of-Concept Study to Assess the Efficacy, Safety and Tolerability of Itepekimab (Anti-IL-33 mAb) in Participants With Non-cystic Fibrosis Bronchiectasis
- A Rhinovirus Challenge Study to Investigate Exacerbations and Immune Responses in Bronchiectasis
- A Safety Trial of DAS181 (FludaseĀ®) in Adult Subjects With Well-Controlled Asthma or Bronchiectasis
- A Series of N-of-1 Trials of Traditional Chinese Medicine Based on Bayesian Method
- A Study of Home-based Pulmonary Rehabilitation and Health Coaching to Treat Bronchiectasis
- A Study of the Clinical Benefit of Tobramycin Inhalation Solution
- A Study to Access Activity and Safety With SAR445399 Compared With Placebo in Participants Aged 18 to 80 Years of Age With Non-Cystic Fibrosis Bronchiectasis
- A Study to Access Safety and Efficacy of Nebulized Tobramycin in Patients With Bronchiectasis
- A Study to Assess the Effectiveness and Safety of GSK3862995B in Adults With Bronchiectasis
- A Study to Evaluate the Diagnostic Performance of Portable Oscillometry Across Chronic Respiratory Diseases
- A Study to Evaluate the Efficacy and Safety of CHF10196 Tablets (Florensocatib) Compared With Placebo in Male and Female Participants 12 to 85 Years of Age With Bronchiectasis
- A Study to Evaluate the Efficacy and Safety of HSK31858 Tablets in Patients with Airway Mucus Hypersecretion
- A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD) and Food Effect of Single or Repeat Doses of GSK2793660 in Healthy Subjects
- A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Inhaled CHF6333 After Single Doses in Healthy Volunteers and After Single and Repeated Doses in Subjects With Bronchiectasis
Drugs in development (20)
- Alvelestat Phase 2
- ALX-009 Phase 1
- Amikacin Phase 2
- Aspartyl-alanyl-diketopiperazine Phase 3
- Azithromycin Phase 3
- Aztreonam lysine Phase 2
- Beclomethasone dipropionate Phase 3
- Brensocatib Phase 3
- Carbocysteine Phase 3
- Ciprofloxacin Phase 3
- Formoterol Phase 3
- Human immunoglobulin G Phase 1
- Icenticaftor Phase 1
- Itepekimab Phase 2
- Itraconazole Phase 3
- Mannitol Phase 3
- Melphalan Phase 2
- Roflumilast Phase 3
- Sodium chloride Phase 3
- Tobramycin Phase 2