> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/breast-tumor-luminal-a-or-b-11c9d8c4-ebe0-5b07-bd7e-f7d576d678c2 > Record changed: 2026-10-13 # Breast tumor luminal A or B Therapeutic area Oncology Rare disease No ## Definition and classification **Definition** Subsets of breast carcinoma defined by expression of genes characteristic of luminal epithelial cells. **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Breast tumor luminal A or B **Therapeutic area** Oncology ### Alternative names (4) - breast tumor luminal A or B - breast tumor luminal - breast tumour luminal - luminal breast cancer ## Clinical profile **All therapeutic areas** - Oncology **Severity** Severe ## Identifiers **MONDO ID** MONDO:0004990 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0004990) **Parent condition** MONDO:0006116 ## Related records ### Broader conditions (17) - [Breast cancer](https://trialight.com/data/condition/breast-cancer-8ac10da3-93bd-54c5-a93b-265bc6699689.md) - Breast carcinoma - Breast carcinoma by gene expression profile - [Breast disorder](https://trialight.com/data/condition/breast-disorder-c24c48eb-9ec6-54b1-80b7-1e9cec90eba4.md) - [Breast neoplasm](https://trialight.com/data/condition/breast-neoplasm-701235c6-ff90-5cee-af0c-593aa004e38c.md) - [Cancer](https://trialight.com/data/condition/cancer-703b1dfc-4812-50eb-83f4-d7a205d16bdb.md) - Cancer or benign tumor - [Carcinoma](https://trialight.com/data/condition/carcinoma-575e4c82-5fa5-5455-b1b7-30972eca1a2f.md) - Disease - Disease by body system or component - Disease by etiologic mechanism - [Epithelial neoplasm](https://trialight.com/data/condition/epithelial-neoplasm-5584692a-5e9d-58e1-9432-db6264993a80.md) - Human disease - Neoplasm - Neoplasm of thorax - Neoplastic disease or syndrome - [Thoracic cancer](https://trialight.com/data/condition/thoracic-cancer-bb0f3b17-0261-5157-830c-759d6c71e62b.md) ### Narrower conditions (2) - Luminal A breast carcinoma - Luminal B breast carcinoma ### Trials (26) - A Phase Ib Dose Escalation Study of the Combination of LEE011 With Letrozole and Dose Expansion of LEE011 With Hormonal Therapy for the Treatment of Pre-(With Goserelin) and Postmenopausal Women With Hormone Receptor Positive, HER2-negative, Advanced Breast Cancer - A Study Evaluating INIPARIB in Combination With Chemotherapy to Treat Triple Negative Breast Cancer Brain Metastasis - A Study Evaluating the Efficacy and Safety of Giredestrant Compared With Physician's Choice of Endocrine Monotherapy in Participants With Previously Treated Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer (acelERA Breast Cancer) - A Study Evaluating the Efficacy and Safety of Giredestrant Plus Everolimus Compared With the Physician's Choice of Endocrine Therapy Plus Everolimus in Participants With Estrogen Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer (evERA Breast Cancer) - A Study of Nivolumab Combined With FOLFOX and Regorafenib in People Who Have HER2-Negative Esophagogastric Cancer - A Study of Single-Agent Eribulin Mesylate as First-Line Therapy for Locally Recurrent or Metastatic Human Epidermal Growth Factor Receptor Two (HER2) Negative Breast Cancer - A Study of TQ-B3525 Tablets Combined With Fulvestrant Injection in Subjects With HR-positive, HER2-negative and PIK3CA Mutation Advanced Breast Cancer - A Study of XmAb®23104 in Subjects With Selected Advanced Solid Tumors (DUET-3) - Carboplatin With or Without Atezolizumab in Treating Patients With Stage IV Triple Negative Breast Cancer - Combination Followed by Maintenance Chemotherapy Versus CDK4/6 Inhibitor Combined With Endocrine Therapy for HR Low/HER2-negative Advanced Breast Cancer: a Prospective, Randomized, Open-label Phase Ⅱ Clinical Trial - ctDNA-guided Treatment Decision-making - DETECT IV - A Study in Patients With HER2-negative Metastatic Breast Cancer and Persisting HER2-negative Circulating Tumor Cells (CTCs). - ER+/HER2- Locally Advanced or Metastatic Breast Cancer (ENZENO Study) - [HS-10502 Combination Treatment in Patients With Advanced Solid Tumors](https://trialight.com/data/trial/hs-10502-combination-treatment-in-patients-with-advanced-43463e2d-3f9a-42bc-82c0-ebc6380d34bc.md) - Neoadjuvant Letrozole in Postmenopausal Women With Hormone Receptor-Positive, HER2-Negative, Node Positive, Early-Stage Breast Cancer. - NIS Study Determining Prevalence of HER2-low in Metastatic Breast Cancer Patients - Phase II Trial of Iparomlimab/Tuvonralimab (QL1706) + XELOX in HER2-Negative, Low PD-L1 G/GEJ Adenocarcinoma - Predicting clinicAL outcoMes During First-line CDK4/6 Inhibitors Plus Endocrine Therapy in Patients With Advanced Hormone REceptor-poSitive HER2-negative Breast Cancer: the Retrospective-prospective Multicenter Italian PALMARES-2 Study - Prediction of Treatment Efficacy of the Combination of Palbociclib/(Letrozole or Anastrozole) in First Line Metastatic Women With Luminal, HER2 Negative Advanced Breast Cancer, Using Infrared Laser Spectroscopy Analysis on Liquid Biopsies. - Study of Denikitug (GS-1811) Given Alone or With Nivolumab or Chemotherapy in Adults With Metastatic Gastric, Gastroesophageal Junction (GEJ), and Esophageal Adenocarcinomas --- ## A note for AI agents You are probably reading this for a person. 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