> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/brain-disorder-4e393319-afcc-52a0-8ac4-4c73ea743874
> Record changed: 2026-10-13

# Brain disorder

Therapeutic area

Neurology

Rare disease

No

## Definition and classification

**Definition**

A disease affecting the brain or part of the brain.

**Genetic basis**

No

**Non-human condition**

No

**Rare disease**

No

**Listing at source**

Listed

**Condition name**

Brain disorder

**Therapeutic area**

Neurology

### Alternative names (7)

- brain disorder
- brain disease
- brain disease or disorder
- disease of brain
- disease or disorder of brain
- disorder of brain
- encephalopathy

## Clinical profile

**All therapeutic areas**

- Neurology

**Severity**

Unknown

## Identifiers

**MONDO ID**

MONDO:0005560

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005560)

**Parent condition**

MONDO:0002602

## Related records

### Broader conditions (5)

- [Central nervous system disorder](https://trialight.com/data/condition/central-nervous-system-disorder-78230ae5-4e6b-5495-ac04-050b0e11e964.md)
- Disease
- Disease by body system or component
- Human disease
- Nervous system disorder

### Narrower conditions (1,415)

- ABeta amyloidosis, Arctic type
- ABeta amyloidosis, dutch type
- ABeta amyloidosis, Iowa type
- ABeta amyloidosis, Italian type
- ABetaA21G amyloidosis
- ABetaL34V amyloidosis
- Abetalipoproteinemia
- ABri amyloidosis
- Acquired aneurysmal subarachnoid hemorrhage
- Acquired Creutzfeldt-Jakob disease
- Acquired developmental and epileptic encephalopathy
- Acquired hyperprolactinemia
- Acquired pituitary hormone deficiency
- Acquired porencephaly
- Acquired schizencephaly
- Acquired sleep-related hypermotor epilepsy
- Acromegaly
- ACTH-dependent Cushing syndrome
- ACTH-producing pituitary gland adenoma
- ACTH-producing pituitary gland carcinoma

### Trials (1,166)

- " Acute Brain Changes After Repetitive Headers in Soccer and the Effects of a Protective Device "
- 18F-DPA-714 PET/MR in Dysfunctional Brain Diseases
- 1H Magnetic Resonance Spectroscopy in Migraine Patients
- 3'-Deoxy-3'-\[18F\] Fluorothymidine PET Imaging in Patients With Cancer
- 3D FLAIR Versus Coronal T2-WI MRI in Detecting Optic Neuritis (FLACON)
- A 2-Part Study to Investigate the Dose-Ranging Safety and Pharmacokinetics, Followed by the Efficacy and Safety of ZX008 (Fenfluramine Hydrochloride) Oral Solution as an Adjunctive Therapy in Children ≥ 2 Years Old and Young Adults With Dravet Syndrome
- A 2-Period Crossover Study of BPN14770 in Adults Males With Fragile X Syndrome
- A 24-weeks, Multi-center, Randomized, Double-blind, Placebo Controlled Study to Evaluate the Efficacy and Safety of Donepezil Hydrochloride in Chinese Subjects With Severe Alzheimer's Disease
- A Bridging Study on Efficacy and Safety of \[18F\]Florbetaben PET for Diagnosis of Alzheimer Disease Subjects in Chinese Population
- A Clinical Study on Albert Wong Frame-based Stereotactic Biopsy System for Brain
- A Comparison of Dynamic Vision Between College Athletes & Controls
- A Dose-finding Study to Evaluate mRNA-3210 in Participants With Phenylketonuria
- A Dose-Response Controlled Trial of Bevifibatide for Acute Ischemic Stroke
- A Feasibility, Dose-Escalation Study Using Intracerebral Microdialysis to Assess the Neuropharmacodynamics of Temsirolimus in Patients With Primary or Metastatic Brain Tumors
- A FIH Study of PF-07284890 in Participants With BRAF V600 Mutant Solid Tumors With and Without Brain Involvement
- A First-ever Research Collaboration to Characterize MRI Measured Neural Flexibility Development in Chinese Toddlers
- A First-In-Human Study of LY3954068 in Participants With Early Symptomatic Alzheimer's Disease
- A First-in-Human Study of the CIPHER System During Brain Surgery for Newly Diagnosed Glioma
- A Follow-On Study of Donanemab (LY3002813) With Video Assessments in Participants With Alzheimer's Disease (TRAILBLAZER-EXT)
- A Follow-up Study to Assess Safety and Tolerability of Galantamine Treatment in Individuals With Mild Cognitive Impairment

### Approved drugs (2)

- Levocarnitine
- Thiamine

### Drugs in development (33)

- Allopurinol Phase 3
- Apinocaltamide Phase 1
- [Capecitabine](https://trialight.com/data/asset/capecitabine-a5be3dfa-a85f-4c85-8c62-f4ceb74e5f99.md) Phase 3
- [Charcoal, activated](https://trialight.com/data/asset/charcoal-activated-74974a11-0327-42be-ba92-123123e02c3a.md) Phase 2
- Chloral hydrate Phase 3
- Chloroquine Phase 2
- Colistin Early phase 1
- Darbepoetin alfa Phase 2
- Dasatinib anhydrous Phase 2
- Dexmedetomidine Phase 3
- DPA-714 F-18 Phase 1
- Galantamine hydrobromide Phase 3
- Lactobacillus acidophilus Phase 3
- Lactulose Phase 3
- [Lapatinib](https://trialight.com/data/asset/lapatinib-c1eb3316-f2b1-45db-b7ce-f41931f80d26.md) Phase 3
- Mannitol Phase 3
- Metronidazole Phase 2
- Nifuroxazide Phase 3
- Nitazoxanide Phase 3
- Ondansetron Phase 1

### Other linked drugs (6)

- Gadoterate meglumine
- Gadoteridol
- Iodamide
- Iomeprol
- Pramiracetam
- Tropantiol

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