> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/brain-cancer-f8f25210-90da-5298-8c6b-4f230fcb45cd > Record changed: 2026-11-04 # Brain cancer Therapeutic area Neurology Rare disease No ## Definition and classification **Definition** A primary or metastatic malignant neoplasm affecting the brain. **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Brain cancer **Therapeutic area** Neurology ### Alternative names (37) - brain cancer - Adult Brain Tumor - Adult Brain Tumors - brain neoplasms, malignant - Brain Tumor Adult - cancer of brain - Cancer of Brain and Nervous System - cancer of the brain - malignant brain neoplasm - malignant brain tumor - Malignant Brain Tumors - malignant neoplasm of brain - malignant neoplasm of the brain - Malignant Primary Brain Tumor - Malignant Primary Brain Tumors - malignant tumor of brain - malignant tumor of the brain - malignant tumour of brain - malignant tumour of the brain - Progressive Malignant Brain Tumor - Recurrent Adult Brain Neoplasm - Recurrent Adult Brain Tumor - Recurrent Malignant Brain Neoplasm - Refractory Malignant Brain Neoplasm - adult brain tumour And 12 more, listed on the interactive page. ## Clinical profile **Severity** Severe ### All therapeutic areas (2) - Neurology - Oncology Sources for recorded values Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0001657) ## Identifiers **MONDO ID** MONDO:0001657 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0001657) **Parent condition** MONDO:0002714 ## Related records ### Broader conditions (16) - [Brain disorder](https://trialight.com/data/condition/brain-disorder-4e393319-afcc-52a0-8ac4-4c73ea743874.md) - Brain neoplasm - [Cancer](https://trialight.com/data/condition/cancer-703b1dfc-4812-50eb-83f4-d7a205d16bdb.md) - Cancer or benign tumor - [Central nervous system cancer](https://trialight.com/data/condition/central-nervous-system-cancer-14789751-67f7-557a-9c07-30e51513747d.md) - [Central nervous system disorder](https://trialight.com/data/condition/central-nervous-system-disorder-78230ae5-4e6b-5495-ac04-050b0e11e964.md) - Central nervous system neoplasm - Disease - Disease by body system or component - Disease by etiologic mechanism - Human disease - [Neoplasm](https://trialight.com/data/condition/neoplasm-2a973797-359b-5982-907e-98f9b7c1a284.md) - Neoplastic disease or syndrome - Nervous system cancer - [Nervous system disorder](https://trialight.com/data/condition/nervous-system-disorder-541eb3ed-9656-574d-babf-28139b060a42.md) - Nervous system neoplasm ### Narrower conditions (93) - ACTH-producing pituitary gland carcinoma - Adult brain ependymoma - Adult brainstem astrocytoma - Adult brainstem glioma - Adult brainstem gliosarcoma - Adult brainstem mixed glioma - Adult pineoblastoma - Brain germinoma - Brain glioblastoma - Brain glioma - Brain oligodendroglioma - Brain sarcoma - Brain stem astrocytic neoplasm - Brain stem ependymoma - Brain stem glioblastoma - Brain stem glioma - Brainstem cancer - Cancer of cerebellum - Central neurocytoma - Cerebellopontine angle embryonal tumor ### Trials (2,512) - (1)H-Nuclear Magnetic Resonance Spectroscopic Imaging of the Brain in Patients Who Receive Neurotoxic Therapy - (11C)dLop as a Marker of P-Glycoprotein Function in Patients With Gliomas - (Concerto) Study of BLU-451 in Advanced Cancers With EGFR Exon 20 Insertion Mutations - \[18F\] FACBC and \[18F\] FLT PET Imaging in Central Nervous System Tumors - \[18F\]Dabrafenib Molecular Imaging in Melanoma Brain Metastasis - \[18F\]DASA-23 and PET Scan in Evaluating Pyruvate Kinase M2 Expression in Patients With Intracranial Tumors or Recurrent Glioblastoma and Healthy Volunteers - \[18F\]FET PET for Characterization of Progressive or Recurrent Glioma From Treatment Related Changes - \[18F\]Fluciclovine and \[18F\]FLT PET/CT Assessment of Primary High-Grade Brain Tumors - \[F-18\] Fluorothymidine (FLT) Imaging on Patients With Primary Brain Tumors - \[F-18\]Fluoro-DOPA PET Imaging of Brain Tumors in Children - 000860: A Phase I/II Study of Zotiraciclib for Recurrent Malignant Gliomas With Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) Mutations - 1 Week Versus 6 Weeks of Levetiracetam in Surgical Brain Tumor Patients - 11C Topotecan PET Imaging - 131-I-TM-601 Study in Adults With Recurrent High-Grade Glioma - 131I-L19SIP Radioimmunotherapy (RIT) in Combination With External Beam Radiation in Patients With Multiple Brain Metastases From Solid Tumors - 18-F-Fluoroacetate as PET Imaging Agent - 18F ML-10 for Early Detection of Response of Brain Metastases to SRS - 18F ML-10 for Early Detection of Response of Brain Metastases to WBRT - 18F-DOPA II - PET Imaging Optimization - 18F-DOPA-PET in Non-tumoral and Tumoral Brain Lesions ### Approved drugs (3) - Lomustine - Motexafin gadolinium - Zinostatin ### Drugs in development (97) - \[18F\]FLUOROMISONIDAZOLE Phase 1 - 4-demethyl-4-cholesteryloxycarbonylpenclomedine Phase 2 - 8H9 131I Phase 1 - ABM-1310 Phase 1 - Acetylcysteine Phase 1 - Afatinib Phase 1 - Aglatimagene besadenovec Phase 3 - Alanosine Phase 2 - Aldesleukin Phase 1 - Aminolevulinic acid Phase 2 - Antineoplaston A10 Phase 2 - Arsenic trioxide Phase 1 - Avutometinib Phase 1 - [Bevacizumab](https://trialight.com/data/asset/bevacizumab-a9e09d09-2d3c-4fda-ad45-01fd000dd363.md) Phase 3 - [Cabazitaxel](https://trialight.com/data/asset/cabazitaxel-9437ae6b-3713-457c-b52b-a71e10a81dde.md) Phase 1 - [Capecitabine](https://trialight.com/data/asset/capecitabine-a5be3dfa-a85f-4c85-8c62-f4ceb74e5f99.md) Phase 2 - [Carboplatin](https://trialight.com/data/asset/carboplatin-91aa6947-1cbb-486a-b5c6-aaaa6868e24e.md) Phase 3 - Carmustine Phase 2 - Cediranib Phase 1 - [Celecoxib](https://trialight.com/data/asset/celecoxib-d2adc66b-f8fb-471f-8779-d55e35cdd52c.md) Phase 2 ### Other linked drugs (1) - 81C6 131I --- ## A note for AI agents You are probably reading this for a person. 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