> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/bipolar-i-disorder-b1dec369-e9f7-586d-ad11-b8275f20481f > Record changed: 2026-10-13 # Bipolar I disorder Therapeutic area Psychiatry Rare disease No ## Definition and classification **Definition** A bipolar disorder that is characterized by at least one manic or mixed episode. **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Bipolar I disorder **Therapeutic area** Psychiatry ### Alternative names (2) - bipolar I disorder - bipolar 1 disorder ## Clinical profile **Severity** Severe ### All therapeutic areas (2) - Neurology - Psychiatry ## Identifiers **MONDO ID** MONDO:0001866 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0001866) **Parent condition** MONDO:0004985 ## Related records ### Broader conditions (11) - Bipolar disorder - [Brain disorder](https://trialight.com/data/condition/brain-disorder-4e393319-afcc-52a0-8ac4-4c73ea743874.md) - [Central nervous system disorder](https://trialight.com/data/condition/central-nervous-system-disorder-78230ae5-4e6b-5495-ac04-050b0e11e964.md) - Disease - Disease by body system or component - Disease by developmental or physiological process - Human disease - [Mental disorder](https://trialight.com/data/condition/mental-disorder-6dfe385f-02c0-52b1-895d-e6ed79c12e5f.md) - [Mood disorder](https://trialight.com/data/condition/mood-disorder-00c37338-ecb8-5997-bb93-d0ec3e6e3573.md) - Nervous system disorder - Psychiatric disorder ### Trials (154) - A Cariprazine Study in the Prevention of Relapse in Bipolar I Disorder Patients Whose Current Episode is Manic or Depressive, With or Without Mixed Features - A Comparison of Olanzapine in Combination With a Mood Stabilizer vs Mood Stabilizer Alone, in Mixed Bipolar Patients - A Double-Blind Randomized Placebo Controlled Study of Quetiapine for the Treatment of Depression in Adolescents With Bipolar Disorder - A Long-Term Study of SM-13496 in Patients With Bipolar I Disorder. - A Multicenter Investigative Study of the Safety and Efficacy of Long-term Administration of Aripiprazole in Combination With Mood Stabilizer for the Treatment of Patients With Bipolar Disorder Experiencing a Manic or Mixed Episode - A Multicenter, Investigative Study of the Safety and Efficacy of Extended Administration of Aripiprazole in Combination With Mood Stabilizer for the Treatment of Patients With Bipolar Disorder Experiencing a Manic or Mixed Episode - A Multicenter, Placebo-controlled, Double-blind Investigative Extension Trial of the Safety and Efficacy of Aripiprazole in the Treatment of Patients With Bipolar Disorder Experiencing a Manic or Mixed Episode - A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel Group-comparison Trial of Aripiprazole in the Treatment of Patients With Bipolar Disorder Experiencing a Manic or Mixed Episode - A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Bipolar Disorder - A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease - A Randomized Study of Azetukalner Versus Placebo in Depressive Episodes Associated With Bipolar I or II Disorder (Bipolar Depression) - A Study for the Treatment of Mania Associated With Bipolar I Disorder in Children and Adolescents - A Study of Aripiprazole in Patients With Bipolar I Disorder With a Major Depressive Episode - A Study of Elpipodect (MK-8189) in Participants With Bipolar I Disorder (MK-8189-020) - A Study of Spoken Language in Mania - A Study to Assess Adverse Events and Change in Disease Activity of Oral Icalcaprant in Adult Participants With Bipolar I or II Disorder - A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive Episodes in Pediatric Participants Participants (10 to 17 Years of Age) With Bipolar I Disorder. - A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Sublingual Asenapine in a Pediatric Population With Schizophrenia or Bipolar I Disorder (P06522 AM1) - A Study to Investigate Lithium Brain/Plasma Pharmacokinetics and Safety of an AL001 Oral Capsule Compared to a Marketed Immediate-release Lithium Carbonate Capsule in Subjects With Bipolar I Disorder - A Trial of Multiple-doses of Aripiprazole in Adults With Schizophrenia or Bipolar 1 Disorder --- ## A note for AI agents You are probably reading this for a person. 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