> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/biliary-tract-neoplasm-5b757066-5940-52f7-aa7d-e5aafdc5b54e > Record changed: 2026-10-13 # Biliary tract neoplasm Therapeutic area Endocrinology Rare disease No ## Definition and classification **Definition** A neoplasm that involves the biliary tract. **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Biliary tract neoplasm **Therapeutic area** Endocrinology ### Alternative names (12) - biliary tract neoplasm - biliary tract neoplasm - biliary tract neoplasm (disease) - biliary tree neoplasm - biliary tree neoplasm (disease) - biliary tree tumor - biliary tree tumour - neoplasm of biliary tree - tumor of biliary tree - tumour of biliary tree - BILIARY\_TRACT - tumour of the extrahepatic bile duct ## Clinical profile **Severity** Severe ### All therapeutic areas (3) - Endocrinology - Gastroenterology - Oncology ## Identifiers **MONDO ID** MONDO:0005304 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005304) **Parent condition** MONDO:0004868 ## Related records ### Broader conditions (16) - Biliary tract disorder - Cancer or benign tumor - [Digestive system disorder](https://trialight.com/data/condition/digestive-system-disorder-ae55641c-32fa-5aa9-ab90-29f763a95dc0.md) - [Digestive system neoplasm](https://trialight.com/data/condition/digestive-system-neoplasm-2ebb9146-1d78-515a-92a3-749515a27d44.md) - Disease - Disease by body system or component - Disease by etiologic mechanism - Endocrine gland neoplasm - [Endocrine system disorder](https://trialight.com/data/condition/endocrine-system-disorder-7bab6998-7c2b-586b-940e-d8d567288d52.md) - Hepatobiliary disorder - Hepatobiliary neoplasm - Human disease - [Liver and intrahepatic bile duct neoplasm](https://trialight.com/data/condition/liver-and-intrahepatic-bile-duct-neoplasm-3f40b188-18f7-5f55-8a6b-3ab9293211bd.md) - [Liver disorder](https://trialight.com/data/condition/liver-disorder-8388d30a-2581-5015-9ddf-adc5f6a331d7.md) - Neoplasm - Neoplastic disease or syndrome ### Narrower conditions (68) - Adenocarcinoma of gallbladder and extrahepatic biliary tract - Adenosquamous bile duct carcinoma - Ampulla of vater adenocarcinoma - Ampulla of vater adenosquamous carcinoma - Ampulla of vater cancer - Ampulla of vater clear cell adenocarcinoma - Ampulla of vater mucinous adenocarcinoma - Ampulla of vater neoplasm - Ampulla of vater small cell neuroendocrine carcinoma - Ampulla of vater squamous cell carcinoma - Ampullary signet ring cell adenocarcinoma - Bile duct adenocarcinoma - Bile duct adenoma - Bile duct cancer - Bile duct carcinoma - Bile duct carcinoma in situ - Bile duct cystadenoma - Bile duct mucinous cystic neoplasm with an associated invasive carcinoma - [Bile duct neoplasm](https://trialight.com/data/condition/bile-duct-neoplasm-cfc3ff17-aae4-586b-a817-37aeb02978b8.md) - Bile duct papillary neoplasm ### Trials (471) - A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A) - A Clinical Study of PD-L1 Antibody ZKAB001 Combined With Capecitabine in Resected Biliary Tract Cancer - A Clinical Study of SHR-A1811 in the Treatment of HER2-positive Locally Advanced or Metastatic Biliary Tract Cancer - A COMPREHENSIVE BIOMARKER EVALUATION IN BILIARY TRACT CANCER - A First-in-human Study Using BDC-1001 as a Single Agent and in Combination With Nivolumab in Advanced HER2-Expressing Solid Tumors - A Phase 1 Dose-escalation Study of FF-10832 for Treatment of Solid Tumors Including Biliary Tract Cancer - A Phase 1 Dose-escalation Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation - A Phase 1 Study of LNCB74 in Advanced Solid Tumors - A Phase 1/1B Study of ST-01156, a Small Molecule RBM39 Degrader, in Patients With Advanced Solid Malignancies - A Phase 1/2 Study of CAN04 in Combination With Different Chemotherapy Regimens in Subjects With Advanced Solid Tumors - A Phase 1/2 Study of INCB001158 in Combination With Chemotherapy in Subjects With Solid Tumors - A Phase 1/2, First-in-Human, Open Label, Dose Escalation Study Of A CSP Targeting Functional Antibody in Solid Tumors - [A Phase 1/2a Study of DB-1303/BNT323 in Advanced/Metastatic Solid Tumors](https://trialight.com/data/trial/a-phase-1-2a-study-of-db-1303-bnt323-in-advanced-metastatic-eb87e354-fdbe-40fd-842a-91d4fc8c2107.md) - A Phase 2 Trial of Regorafenib as A Single Agent in Advanced and Metastatic Biliary Tract Carcinoma/Cholangiocarcinoma Patients Who Have Failed First-line Chemotherapy - A Phase 3b, Open-label, Multi-center Study on Durvalumab in Combination With Gemcitabine-based Chemotherapy as 1L Treatment for the Chinese Patients With Unresectable Biliary Tract Cancers (BTC) - A Phase I Study of Adjuvant Chemotherapy With GC in Biliary Tract Cancer Undergoing Resection Without Major Hepatectomy - A Phase I Study of Adjuvant Chemotherapy With GS in Biliary Tract Cancer Undergoing Resection Without Major Hepatectomy - A Phase I, Open-Label, Multicentre Study to Evaluate the Safety, Tolerability and Pharmacokinetics of MEDI4736 in Patients With Advanced Solid Tumours - A Phase I/II Study of Regorafenib Plus Avelumab in Solid Tumors - A Phase I/II Study of the Pan-immunotherapy in Patients With Local Advanced/Metastatic BTC ### Approved drugs (1) - [Zanidatamab](https://trialight.com/data/asset/zanidatamab-290ceeba-1188-42f7-8c41-3c32c24922eb.md) ### Drugs in development (37) - Axitinib Phase 2 - [Benmelstobart](https://trialight.com/data/asset/benmelstobart-2bff71aa-d2ac-4a5a-9949-c935954a2314.md) Phase 2 - [Binimetinib](https://trialight.com/data/asset/binimetinib-f5914744-65e2-4d8c-8482-9f51a406315e.md) Phase 3 - [Capecitabine](https://trialight.com/data/asset/capecitabine-a5be3dfa-a85f-4c85-8c62-f4ceb74e5f99.md) Phase 3 - Cediranib Phase 2 - [Cetuximab](https://trialight.com/data/asset/cetuximab-a1f8c65c-bae1-4b77-9491-dca37aeeaa3c.md) Phase 2 - [Cisplatin](https://trialight.com/data/asset/cisplatin-e039621a-d679-4740-88ac-94842bf4a91e.md) Phase 3 - CM-4307 Phase 2 - [Docetaxel](https://trialight.com/data/asset/docetaxel-3c835086-a86f-4a89-abb6-45847fbab5d6.md) Phase 2 - [Durvalumab](https://trialight.com/data/asset/durvalumab-bca7c265-7862-46e1-bf29-3dd2fdda4954.md) Phase 3 - Encorafenib Phase 3 - [Envafolimab](https://trialight.com/data/asset/envafolimab-067ce798-3523-4c36-9d89-3452238113d3.md) Phase 2 - [Fluorouracil](https://trialight.com/data/asset/fluorouracil-f8444d73-5c73-4f35-aa71-67d578277450.md) Phase 3 - Futibatinib Phase 3 - [Gemcitabine](https://trialight.com/data/asset/gemcitabine-40c84c8f-1f08-4402-bce9-f31ff283382e.md) Phase 3 - Hydroxychloroquine Phase 2 - [Ipilimumab](https://trialight.com/data/asset/ipilimumab-06c42b29-e333-4f3c-94fe-dbea5fe48cd4.md) Phase 2 - Irinotecan Phase 2 - Ivosidenib Phase 3 - [Lenvatinib](https://trialight.com/data/asset/lenvatinib-44bdd81b-9a97-4a26-9b2b-0d1d8fd79032.md) Phase 2 --- ## A note for AI agents You are probably reading this for a person. 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