> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/b-cell-neoplasm-ffd0710d-7dbd-55bc-a4a5-3c1cf532bac2 > Record changed: 2026-10-13 # B-cell neoplasm Therapeutic area Hematology Rare disease No ## Definition and classification **Definition** A group of heterogeneous lymphoid tumors generally expressing one or more B-cell antigens or representing malignant transformations of B-lymphocytes. **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** B-cell neoplasm **Therapeutic area** Hematology ### Alternative names (3) - B-cell neoplasm - B-cell neoplasm - lymphoma, B-cell ## Clinical profile **Severity** Unknown ### All therapeutic areas (3) - Hematology - Immunology - Oncology ## Identifiers **MONDO ID** MONDO:0004095 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0004095) **Parent condition** MONDO:0004805 ## Related records ### Broader conditions (15) - Cancer or benign tumor - Disease - Disease by body system or component - Disease by etiologic mechanism - Hematologic disorder - [Hematopoietic and lymphoid cell neoplasm](https://trialight.com/data/condition/hematopoietic-and-lymphoid-cell-neoplasm-ed3616fa-22fe-5984-94b4-745416e01ef9.md) - [Hematopoietic and lymphoid system neoplasm](https://trialight.com/data/condition/hematopoietic-and-lymphoid-system-neoplasm-510101ac-7ce5-5dd1-8980-f2f110effdf0.md) - Human disease - [Immune system disorder](https://trialight.com/data/condition/immune-system-disorder-24846188-b462-515c-bb34-142255a648c8.md) - Leukocyte disorder - Lymphoid hemopathy - Lymphoid neoplasm - [Lymphoma](https://trialight.com/data/condition/lymphoma-de4db685-7419-5e0e-b958-4591ffd69d43.md) - Neoplasm - Neoplastic disease or syndrome ### Narrower conditions (128) - A53 diffuse large B-cell lymphoma - Aggressive B-cell non-Hodgkin lymphoma - ALK-positive large B-cell lymphoma - Alpha-heavy chain disease - B acute lymphoblastic leukemia with DUX4 rearrangement - B acute lymphoblastic leukemia with PAX5 P80R mutation - B-cell acute lymphoblastic leukemia - B-cell acute lymphoblastic leukemia with t(1;19)(q23;p13.3); E2A-PBX1 (TCF3-PBX1) - B-cell adult acute lymphocytic leukemia - B-cell childhood acute lymphoblastic leukemia - [B-cell chronic lymphocytic leukemia](https://trialight.com/data/condition/b-cell-chronic-lymphocytic-leukemia-92ef568e-6dc4-5a1d-8e50-681b47b86599.md) - [B-cell non-Hodgkin lymphoma](https://trialight.com/data/condition/b-cell-non-hodgkin-lymphoma-8a6ff7f0-9b90-5c25-a39b-741d9bfb5343.md) - B-cell prolymphocytic leukemia - B-lymphoblastic leukemia with MEF2D rearrangement - B-lymphoblastic leukemia with MYC rearrangement - B-lymphoblastic leukemia with NUTM1 rearrangement - B-lymphoblastic leukemia with PAX5alt - B-lymphoblastic leukemia with TCF3-HLF fusion - B-lymphoblastic leukemia with ZNF384 rearrangement - B-lymphoblastic leukemia/lymphoma MLL rearranged ### Trials (774) - 1630GCC: Zydelig Maintenance in B-Cell Non-Hodgkin's Lymphoma After Autologous Stem Cell Transplantation - 18F-FSPG PET/CT for Cancer Patients on Therapy - a Clinical Research of CD19 and CD22 Targeted Prime CAR-T Cell in Relapsed/Refractory B Cell Lymphoma - A Clinical Research of CD22-Targeted CAR-T in B Cell Malignancies - A Clinical Study Evaluating the Safety and Efficacy of BinD19 Treatment in Childhood R/R ALL and Lymphoma Subjects - A Clinical Study Evaluating the Safety and Efficacy of GT801 Injection in Adult Patients With Relapsed/Refractory CD19-positive B-cell Hematologic Malignancies and Autoimmune Hemolytic Anemia - A Clinical Study Exploring CT1190B in the Treatment of Patients with Relapsed/refractory B-cell Non-Hodgkin Lymphoma - A Clinical Study Exploring CT1190B in the Treatment of Patients With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma - A Clinical Study Exploring CT1190B in the Treatment of Patients With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma ( CT1190B-CG11001 ) - A Clinical Study Exploring CT1190B in the Treatment of Patients With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma ( CT1190B-CG1101 ) - A Clinical Study Exploring CT1194C in Patients With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma - A Clinical Study Exploring the Safety, Efficacy and Metabolic Kinetics of CT1182 Injection in Patients With Relapsed / Refractory Non Hodgkin Lymphoma - A Clinical Study of Allogeneic CD19/BCMA CAR-T Cells for the Treatment of R/R B-cell Malignant Tumors - A Clinical Study of CAR-T Cells Treatment for Children With CD19+/CD22+ R/R ALL and Lymphoma - A Clinical Study of CD19 Targeted CAR-T for Patients With CD19+ Lymphoma and Leukemia - A Clinical Study of Injectable IMM0306 in Combination With Lenalidomide - A Clinical Study of of RN1701 Injection in the Treatment of Relapsed/Refractory B-Cell Lymphomas - A Clinical Study of ONCT-808 in Subjects With Relapsed or Refractory B-Cell Malignancies - A Clinical Study of SHR-3079 in B-cell Non-Hodgkin Lymphoma - A Clinical Study to Evaluate the Efficacy and Safety of TQB3702 Tablets Combined With Immunochemotherapy for the Treatment of B-cell Lymphoma ### Approved drugs (2) - [Loncastuximab tesirine](https://trialight.com/data/asset/loncastuximab-tesirine-a37d802c-da76-404a-83d2-de625c048f90.md) - [Polatuzumab vedotin](https://trialight.com/data/asset/polatuzumab-vedotin-0d7ba42f-27fc-4954-85ff-18eee7fdddc9.md) ### Drugs in development (1) - [Bortezomib](https://trialight.com/data/asset/bortezomib-35a853cf-26ab-4a4c-a405-ae671d364aad.md) Phase 2 --- ## A note for AI agents You are probably reading this for a person. 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