> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/autoimmune-thrombocytopenic-purpura-b2da2407-0fb5-5196-bf62-e72dbd3961b2 > Record changed: 2026-10-29 # Autoimmune thrombocytopenic purpura Therapeutic area Immunology Rare disease Yes ## Definition and classification **Definition** An autoimmune disorder in which the number of circulating platelets is reduced due to their antibody-mediated destruction. ITP is a diagnosis of exclusion and is heterogeneous in origin. **Genetic basis** Yes **Non-human condition** No **Rare disease** Yes **Listing at source** Listed **Condition name** Autoimmune thrombocytopenic purpura **Therapeutic area** Immunology ### Alternative names (10) - autoimmune thrombocytopenic purpura - immune thrombocytopenia - ITP - autoimmune thrombocytopenic purpura - idiopathic thrombocytopenia - idiopathic thrombocytopenia purpura - idiopathic thrombocytopenic purpura - thrombocytopenic purpura, autoimmune - AITP - thrombocytopenic purpura autoimmune ## Clinical profile **Severity** Severe ### All therapeutic areas (2) - Hematology - Immunology ## Identifiers **MONDO ID** MONDO:0008558 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0008558) **Parent condition** MONDO:0004680 ## Related records ### Broader conditions (16) - [Autoimmune disease](https://trialight.com/data/condition/autoimmune-disease-8a8fd8aa-2d04-5f24-b839-ba96a70c11e9.md) - Autoimmune disorder of blood - Autoimmune thrombocytopenia - Blood coagulation disease - Blood platelet disease - Disease - Disease by body system or component - Hematologic disorder - Hemorrhagic disease - Human disease - [Immune system disorder](https://trialight.com/data/condition/immune-system-disorder-24846188-b462-515c-bb34-142255a648c8.md) - Primary thrombocytopenia - [Purpura](https://trialight.com/data/condition/purpura-43678661-d964-58db-bb3c-bf2ec6c13b09.md) - Thrombocytopenia - Thrombocytopenic purpura - Thrombotic microangiopathy ### Trials (165) - A Chart Review of Rituximab Plus Repeated Cycles of Dexamethasone - A Clinical Study in Patients With Chronic Idiopathic Thrombocytopenic Purpura in R788 - A First in HumanTrial to Evaluate The Safety, Tolerability, And Pharmacokinetics Of PF-06755347 - A Follow-up Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia - A Long-term Study to Assess the Safety and Efficacy of Efgartigimod in Adult Patients With Primary Immune Thrombocytopenia (ITP). - A Phase 1b/2a Study of Budoprutug in Subjects With Immune Thrombocytopenia (ITP) - A Phase 3 Study to Evaluate the Safety and Efficacy of Efgartigimod PH20 Subcutaneous in Adult Patients With Primary Immune Thrombocytopenia - A Phase 3, Multicenter, Randomized, Double-blind,Active-controlled, Parallel-group Trial With an Open-labelExtension Phase to Evaluate the Efficacy and Safety of OralE5501 Versus Eltrombopag, in Adults With Chronic ImmuneThrombocytopenia (Idiopathic Thrombocytopenic Purpura) - A Phase I Study of Recombinant Human CD4 Immunoglobulin G (rCD4-lgG) in Patients With HIV-Associated Immune Thrombocytopenic Purpura - A Phase Ib/II Clinical Trial of Multiple Doses of STSA-1301 Subcutaneous Injection in Healthy Subjects and Patients With Immune Thrombocytopenia (ITP) - A PHASE II TRIAL AIMING TO INVESTIGATE THE SAFETY AND CLINICAL ACTIVITY OF BELANTAMAB MAFODOTIN IN ADULT PATIENTS WITH PRIMARY IMMUNE THROMBOCYTOPENIA PREVIOUSLY TREATED WITH A THROMBOPOIETIN RECEPTOR AGONIST AND/OR RITUXIMAB AFTER CORTICOSTEROID FIRST-LINE THERAPY - A Study Evaluating the Addition of MabThera (Rituximab) to Standard Treatment in Patients With Idiopathic Thrombocytopenic Purpura (ITP) - A Study in Healthy Subjects to Evaluate Bioavailability of 4 Formulations of E5501 - A Study Investigating Intravenous Human Normal Immunoglobulin 10% in Adults With Chronic Immune Thrombocytopenia (ITP) - A Study of Efficacy and Safety of Ianalumab Versus Placebo in Addition to Eltrombopag in Primary Immune Thrombocytopenia Patients Who Failed Steroids - A Study of Efgartigimod IV in Participants From 12 Years to Less Than 18 Years of Age With Chronic Immune Thrombocytopenia (ITP) - A Study of Ianalumab (VAY736) in Patients With Primary Immune Thrombocytopenia (ITP) Previously Treated With at Least Two Lines of Therapies - A Study of Ianalumab in Addition to Eltrombopag in Pediatric Patients With Primary ITP Who Failed Corticosteroids. - A Study of MabThera (Rituximab) in Patients With Idiopathic Thrombocytopenic Purpura. - A Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia ### Approved drugs (9) - Cortisone acetate - [Dexamethasone](https://trialight.com/data/asset/dexamethasone-b923ddae-f095-408c-96e9-975238a429ad.md) - Dexamethasone sodium phosphate - Eltrombopag choline - Eltrombopag olamine - Fostamatinib disodium - [Human immunoglobulin G](https://trialight.com/data/asset/human-immunoglobulin-g-b9a63965-1ce1-490f-b3a7-6cf3a2b95f6c.md) - [Prednisone](https://trialight.com/data/asset/prednisone-a5a99f90-5fbe-45c2-a625-34ba78735da6.md) - Romiplostim ### Drugs in development (63) - [Acetaminophen](https://trialight.com/data/asset/acetaminophen-04ea33a5-49ee-4a1b-ad16-54627012140e.md) Phase 1 - Acetylcysteine Phase 2 - Alemtuzumab Phase 2 - [Aspirin](https://trialight.com/data/asset/aspirin-03870fc6-137e-47aa-9f14-b7ae6754fb15.md) Phase 2 - Atorvastatin Phase 2 - Avatrombopag Phase 3 - [Baricitinib](https://trialight.com/data/asset/baricitinib-dde0cdc5-8f75-41b1-bc92-b187471c63df.md) Phase 2 - Batoclimab Phase 2 - Belimumab Phase 3 - Bevifimod Phase 1 - Blisibimod Phase 2 - [Bortezomib](https://trialight.com/data/asset/bortezomib-35a853cf-26ab-4a4c-a405-ae671d364aad.md) Phase 3 - Briobacept Phase 2 - Caffeic acid Phase 3 - Ciprofloxacin Phase 1 - [Cyclophosphamide](https://trialight.com/data/asset/cyclophosphamide-25b75968-e3cd-410a-9b24-0c349d8f7663.md) Phase 2 - Cyclosporine Phase 3 - Danazol Phase 2 - [Daratumumab](https://trialight.com/data/asset/daratumumab-28c327e5-1741-4dd5-89d4-6562e941ab50.md) Phase 2 - Dazodalibep Phase 1 ### Other linked drugs (4) - Esomeprazole magnesium - [Sirolimus](https://trialight.com/data/asset/sirolimus-08da04e4-ea95-4587-95c4-83d583e56570.md) - Valziflocept - Vonoprazan fumarate --- ## A note for AI agents You are probably reading this for a person. 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