> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/atherosclerosis-5dab64e9-1fd4-5dd2-90c2-ce84935652d1 > Record changed: 2026-10-13 # Atherosclerosis Therapeutic area Vascular Medicine Rare disease No ## Definition and classification **Definition** A disease characterized by the build-up of fatty material and calcium deposition in the arterial wall resulting in partial or complete occlusion of the arterial lumen. **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Atherosclerosis **Therapeutic area** Vascular Medicine ### Alternative names (2) - atherosclerosis - atherosclerosis of artery ## Clinical profile **Severity** Severe ### All therapeutic areas (2) - Cardiology - Vascular Medicine ## Identifiers **MONDO ID** MONDO:0005311 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005311) **Parent condition** MONDO:0002277 ## Related records ### Broader conditions (7) - Arterial disorder - [Arteriosclerosis disorder](https://trialight.com/data/condition/arteriosclerosis-disorder-ccf5bc55-a56d-5e65-aae3-11b35e37d15b.md) - [Cardiovascular disorder](https://trialight.com/data/condition/cardiovascular-disorder-362e433e-88a4-575f-90af-50fe7239dec0.md) - Disease - Disease by body system or component - Human disease - Vascular disorder ### Narrower conditions (9) - Aortic atherosclerosis - Arteriolosclerosis - Arteriosclerosis obliterans - [Atherosclerotic cardiovascular disease](https://trialight.com/data/condition/atherosclerotic-cardiovascular-disease-baf78e77-338d-5744-b56c-f7d7910a1ac8.md) - Autoimmune atherosclerosis - Cerebral atherosclerosis - Coronary atherosclerosis - Generalized atherosclerosis - Renal artery atheroma ### Trials (1,470) - "Detection and Follow-up of Coronary Lesions in HeFH (DESTINY-FH Study)" - "Immunoregulation in Atherosclerosis: A Single-Cell RNA Sequencing Study" - \[18F\]AlF-NOTA-octreotide PET/MRI in Carotid Artery Disease - 11C-PIB PET Study in MESA at Columbia University - 12-week Open-label, Phase IIIb Comparing Efficacy and Safety of Rosuvastatin (CRESTOR™) in Combination With Ezetimibe - 18F-fluorocholine PET-MR Imaging of Coronary Plaque Vulnerability - 18F-Flutemetamol and Plaque Vulnerability - 18F-Sodium Fluoride (18F-NaF) PET-CT Imaging to Identify Vulnerable Plaques in Patients With Diabetes - 3D/4D Ultrasound Contrast Enhanced Imaging (CEUS) for Carotid Plaque Vulnerability - 480 Biomedical Bioresorbable Scaffold System in the Treatment of de Novo Superficial Femoral Artery (SFA) Lesions - 68Ga-FAPI PET/MR for Atherosclerosis - 7 Year Follow-up Study of the DanRisk Population - A Blinded Study Conducted at Multiple Centers Evaluating Various Doses of an Investigational Agent (BO-653) Against Placebo, for Safety and Effectiveness in Preventing Post-Angioplasty Blood Vessel Re-Closure (Restenosis) in Stented Vessels. - A Clinical and Histological Analysis of Mesenchymal Stem Cells in Amputation - A Clinical Study of IMC-001 for Injection in Improving Atherosclerotic Plaque Stability in Patients With Acute Coronary Syndrome. - A Clinical Trial Comparing Cangrelor to Clopidogrel Standard Therapy in Subjects Who Require Percutaneous Coronary Intervention (PCI) (CHAMPION PHOENIX) - A Clinical Trial to Confirm Safety & Effectiveness of the SYNERGY 4.50 mm and 5.00 mm Stent for Treatment of Atherosclerotic Lesion(s) - A Cohort Study on Cardiovascular and Cerebrovascular Outcomes - A Coronary Computed Tomography Angiography-guided Intervention for High Risk Cardiovascular Disease Population in Rural China - A Cross-sectional Study of Lipoprotein(a) Levels in Patients With Documented History of Atherosclerotic Cardiovascular Disease (ASCVD) ### Approved drugs (7) - [Alirocumab](https://trialight.com/data/asset/alirocumab-94bb5dc8-32f2-4ed6-a82e-b554472e2cd5.md) - Bempedoic acid - [Inclisiran sodium](https://trialight.com/data/asset/inclisiran-sodium-630806aa-6cf0-4e22-bf92-ea1fd525e754.md) - Lovastatin - Niacin - Pravastatin sodium - Rosuvastatin calcium ### Drugs in development (73) - Acarbose Phase 3 - Aliskiren Phase 2 - [Amlodipine](https://trialight.com/data/asset/amlodipine-b06f8f1a-f55d-4a6b-b513-c6443387d4ae.md) Phase 3 - Anacetrapib Phase 3 - Ascorbic acid Phase 2 - [Aspirin](https://trialight.com/data/asset/aspirin-03870fc6-137e-47aa-9f14-b7ae6754fb15.md) Phase 3 - Atorvastatin Phase 3 - Atreleuton Phase 2 - [Baxdrostat](https://trialight.com/data/asset/baxdrostat-a2e43871-8326-4540-9aa3-5a6511c12d97.md) Phase 1 - Benazepril Phase 3 - BMS-582949 Phase 2 - BMS-779788 Phase 1 - BMS-962476 Phase 1 - [Canakinumab](https://trialight.com/data/asset/canakinumab-7cd74b21-082d-4a09-8847-aa6d401bc853.md) Phase 3 - Candesartan cilexetil Phase 3 - Carvedilol Phase 3 - Chlorothiazide Phase 3 - Chlorthalidone Phase 3 - Cilostazol Phase 3 - Clopidogrel Phase 3 ### Other linked drugs (2) - Fluvastatin - Sarpogrelate --- ## A note for AI agents You are probably reading this for a person. 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