> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/astrocytoma-excluding-glioblastoma-dd29b6db-5e3d-590d-b093-7a770a5facb2
> Record changed: 2026-10-13

# Astrocytoma (excluding glioblastoma)

Therapeutic area

Neurology

Rare disease

No

## Definition and classification

**Definition**

A tumor of the brain or spinal cord showing astrocytic differentiation. It includes the following clinicopathological entities: pilocytic astrocytoma, diffuse astrocytoma, anaplastic astrocytoma, pleomorphic xanthoastrocytoma, and subependymal giant cell astrocytoma.

**Genetic basis**

No

**Non-human condition**

No

**Rare disease**

No

**Listing at source**

Listed

**Condition name**

Astrocytoma (excluding glioblastoma)

**Therapeutic area**

Neurology

### Alternative names (2)

- astrocytoma (excluding glioblastoma)
- astrocytoma

## Clinical profile

**Severity**

Moderate

### All therapeutic areas (2)

- Neurology
- Oncology

## Identifiers

**MONDO ID**

MONDO:0019781

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0019781)

**Parent condition**

MONDO:0021636

## Related records

### Broader conditions (12)

- Astrocytic tumor
- Cancer or benign tumor
- Disease
- Disease by body system or component
- Disease by etiologic mechanism
- [Glioma](https://trialight.com/data/condition/glioma-4ac240c4-7ffb-5f08-b793-0b205a4b5d03.md)
- Human disease
- Neoplasm
- Neoplastic disease or syndrome
- Nervous system disorder
- Nervous system neoplasm
- Neuroepithelial neoplasm

### Narrower conditions (37)

- Adult brainstem astrocytoma
- Anaplastic astrocytoma
- Astrocytoma, IDH-mutant, grade 2
- Astrocytoma, IDH-mutant, grade 3
- Astrocytoma, IDH-mutant, grade 4
- Brain astrocytoma
- Brain stem astrocytic neoplasm
- Cauda equina intradural extramedullary astrocytoma
- Cerebellar astrocytoma
- Cerebellar pilocytic astrocytoma
- Cerebral astrocytoma
- Childhood brainstem astrocytoma
- Childhood cerebellar astrocytic neoplasm
- Childhood cerebral astrocytoma
- Childhood optic tract astrocytoma
- Childhood pilocytic astrocytoma
- Diencephalic astrocytomas
- Diffuse astrocytoma
- Diffuse astrocytoma, MYB- or MYBL1-altered
- Fibrillary astrocytoma

### Trials (672)

- (11C)dLop as a Marker of P-Glycoprotein Function in Patients With Gliomas
- 131-I-TM-601 Study in Adults With Recurrent High-Grade Glioma
- 18F-FDOPA PET/CT or PET/MRI in Measuring Tumors in Patients With Newly-Diagnosed or Recurrent Gliomas
- 3D Prediction of Patient-Specific Response
- 3T MRI Biomarkers of Glioma Treatment Response
- 5-ALA in Recurrent Glioma
- A Biospecimen Collection Study in BRAF-V600E Mutated Recurrent Gliomas
- A Continuation Protocol for Patients Previously Enrolled in a Study of Toca 511
- A Feasibility, Dose-Escalation Study Using Intracerebral Microdialysis to Assess the Neuropharmacodynamics of Temsirolimus in Patients With Primary or Metastatic Brain Tumors
- A Phase 1, Open-Label, Dose Escalation Study of ANG1005 in Patients With Malignant Glioma
- A Phase I Dose Finding and Safety Study of Oral LDE225 in Children and a Phase II Portion to Assess Preliminary Efficacy in Recurrent or Refractory MB
- A Phase I Study of ABT-888, an Oral Inhibitor of Poly(ADP-ribose) Polymerase and Temozolomide in Children With Recurrent/Refractory CNS Tumors
- A Phase I Study of AdV-tk + Prodrug Therapy in Combination With Radiation Therapy for Pediatric Brain Tumors
- A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas
- A Phase I Trial of Nanoliposomal CPT-11 (NL CPT-11) in Patients With Recurrent High-Grade Gliomas
- A Phase I/II Trial of BMS-247550 for Treatment of Patients With Recurrent High-Grade Gliomas
- A Phase I/IIa Study of Cerebraca Wafer Plus Adjuvant Temozolomide (TMZ) in Patients With Recurrent High Grade Glioma
- A Phase IB 2 Dose Trial of IRS-1 HSV C134 (IND 17296) Administered Intratumorally in Patients With Recurrent Malignant Glioma
- A Phase II Study of Temozolomide and O6-Benzylguanine (O6-BG) in Patients With Temozolomide-Resistant Anaplastic Glioma
- A Phase II Trial of Sutent (Sunitinib; SU011248) for Recurrent Anaplastic Astrocytoma and Glioblastoma

### Approved drugs (3)

- Carmustine
- [Everolimus](https://trialight.com/data/asset/everolimus-0edf09a9-672d-4f9a-9e34-21ab083a92a4.md)
- Vorasidenib

### Drugs in development (38)

- Antineoplaston A10 Phase 2
- [Atezolizumab](https://trialight.com/data/asset/atezolizumab-2cce6944-73b7-49f4-8125-4e6747997b82.md) Phase 2
- [Bevacizumab](https://trialight.com/data/asset/bevacizumab-a9e09d09-2d3c-4fda-ad45-01fd000dd363.md) Phase 2
- BMX-001 Phase 2
- Cabozantinib S-malate Phase 2
- [Carboplatin](https://trialight.com/data/asset/carboplatin-91aa6947-1cbb-486a-b5c6-aaaa6868e24e.md) Phase 3
- Chlorotoxin Phase 2
- Cintredekin besudotox Phase 1
- [Denifanstat](https://trialight.com/data/asset/denifanstat-a6eb2f97-dc37-46fa-a576-5f0a79df6d1a.md) Phase 2
- Disufenton sodium Phase 1
- Doxorubicin Phase 2
- Erlotinib Phase 1
- Etoposide Phase 2
- Guanine Phase 2
- Hiltonol Phase 1
- [Hydroxyurea](https://trialight.com/data/asset/hydroxyurea-a56eda3c-3ef0-4ca7-b972-656091c627a5.md) Phase 3
- Icapamespib Phase 1
- [Imatinib mesylate](https://trialight.com/data/asset/imatinib-mesylate-228c51e4-aef9-4351-8581-568722f6cb78.md) Phase 3
- [Influenza virus vaccine](https://trialight.com/data/asset/influenza-virus-vaccine-99390506-afe0-4b83-a4c7-b7a43c41cb19.md) Phase 2
- Irinotecan Phase 2

---

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