> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/angioimmunoblastic-t-cell-lymphoma-5b697108-b9cf-53e9-afde-71a36bf55d6b > Record changed: 2026-10-13 # Angioimmunoblastic T-cell lymphoma Therapeutic area Hematology Rare disease Yes ## Definition and classification **Definition** A mature T-cell non-Hodgkin lymphoma, characterized by systemic disease and a polymorphous infiltrate involving lymph nodes and extranodal sites. The clinical course is typically aggressive. **Genetic basis** No **Non-human condition** No **Rare disease** Yes **Listing at source** Listed **Condition name** Angioimmunoblastic T-cell lymphoma **Therapeutic area** Hematology ### Alternative names (11) - angioimmunoblastic T-cell lymphoma - AILD - AILT - T-cell lymphoma, AILD type - angioimmunoblastic T-cell lymphoma - angioimmunoblastic lymphadenopathy - angioimmunoblastic lymphadenopathy type T-cell lymphoma - angioimmunoblastic lymphadenopathy with Dysproteinemia - immunoblastic lymphadenopathy - lymphogranulomatosis X - AITL ## Clinical profile **Severity** Severe ### All therapeutic areas (2) - Hematology - Oncology ## Identifiers **MONDO ID** MONDO:0004977 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0004977) **Parent condition** MONDO:0000430 ## Related records ### Broader conditions (18) - Cancer or benign tumor - Disease - Disease by body system or component - Disease by etiologic mechanism - Hematologic disorder - [Hematopoietic and lymphoid cell neoplasm](https://trialight.com/data/condition/hematopoietic-and-lymphoid-cell-neoplasm-ed3616fa-22fe-5984-94b4-745416e01ef9.md) - [Hematopoietic and lymphoid system neoplasm](https://trialight.com/data/condition/hematopoietic-and-lymphoid-system-neoplasm-510101ac-7ce5-5dd1-8980-f2f110effdf0.md) - Human disease - Lymphoid hemopathy - Lymphoid neoplasm - [Lymphoma](https://trialight.com/data/condition/lymphoma-de4db685-7419-5e0e-b958-4591ffd69d43.md) - Mature T-cell and NK-cell non-Hodgkin lymphoma - Neoplasm - Neoplasm of mature T-cells or NK-cells - Neoplastic disease or syndrome - [Non-Hodgkin lymphoma](https://trialight.com/data/condition/non-hodgkin-lymphoma-9fc07e31-fd30-5055-991f-04d10cc1f646.md) - T-cell and NK-cell neoplasm - T-cell non-Hodgkin lymphoma ### Trials (276) - 12-O-Tetradecanoylphorbol-13-acetate in Treating Patients With Hematologic Cancer or Bone Marrow Disorder - 17-Dimethylaminoethylamino-17-demethoxygeldanamycin (17-DMAG) in Treating Patients With an Advanced Solid Tumor or Lymphoma - 17-DMAG in Treating Patients With Metastatic or Unresectable Solid Tumors or Lymphomas - 17-N-Allylamino-17-Demethoxygeldanamycin and Bortezomib in Treating Patients With Relapsed or Refractory Hematologic Cancer - 17-N-Allylamino-17-Demethoxygeldanamycin in Treating Patients With Advanced Epithelial Cancer, Malignant Lymphoma, or Sarcoma - 3-AP and Gemcitabine in Treating Patients With Advanced Solid Tumors or Lymphoma - 3'-Deoxy-3'-\[18F\] Fluorothymidine PET Imaging in Patients With Cancer - 506U78 in Treating Patients With Lymphoma - 506U78 in Treating Patients With Recurrent or Refractory Non-Hodgkin's Lymphoma or T-cell Lymphoma - A Phase 1b/2 Study of Intravenous Brincidofovir in Patients With Relapsed or Refractory Lymphoma and Relapsed or Refractory Extranodal Natural Killer/T-cell Lymphoma - A Phase I Trial Anti-CC Chemokine Receptor 4 Chimeric Antigen Receptor T Cells (CCR4 CAR T Cells) for CCR4 Expressing T-cell Malignancies Including Peripheral T-cell Non-Hodgkin Lymphoma (PTCL) and Cutaneous T-cell Non-Hodgkin Lymphoma (CTCL) - A Phase II Study of Single Agent Brentuximab Vedotin in Relapsed/Refractory CD30 Low (<10%) Mature T Cell Lymphoma (TCL) - A Registry for People With T-cell Lymphoma - A Retrospective Study on Extranodal Lymphoma or Lymphoma of Rare Pathological Types - [A Study of ARV-393 in Relapsed/Refractory Non-Hodgkin Lymphoma.](https://trialight.com/data/trial/a-study-of-arv-393-in-relapsed-refractory-non-hodgkin-8162376a-30e8-4655-8342-515c1a4f2661.md) - A Study of Duvelisib Versus Gemcitabine or Bendamustine in Participants With Relapsed/Refractory Nodal T Cell Lymphoma With T Follicular Helper (TFH) Phenotype - A Study to Assess the Safety, Tolerability, Efficacy, and Drug Levels of BMS-986369 (Golcadomide) in Participants With Relapsed or Refractory T-cell Lymphomas in Japan (GOLSEEK-3) - A Vaccine (VSV-hIFNβ-NIS) With or Without Cyclophosphamide and Combinations of Ipilimumab, Nivolumab, and Cemiplimab in Treating Relapsed or Refractory Multiple Myeloma, Acute Myeloid Leukemia or Lymphoma - Alefacept in Treating Patients With Relapsed or Refractory Cutaneous T-Cell Lymphoma or Peripheral T-Cell Non-Hodgkin's Lymphoma - Alemtuzumab and Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage II, Stage III, or Stage IV T-Cell Non-Hodgkin's Lymphoma ### Drugs in development (25) - Alemtuzumab Phase 3 - [Azacitidine](https://trialight.com/data/asset/azacitidine-4f3798ea-680c-4288-a367-118b7bfe411f.md) Phase 3 - [Bendamustine](https://trialight.com/data/asset/bendamustine-07f7a21f-820a-4423-a534-0d6d0380b382.md) Phase 3 - [Cisplatin](https://trialight.com/data/asset/cisplatin-e039621a-d679-4740-88ac-94842bf4a91e.md) Phase 2 - [Cyclophosphamide](https://trialight.com/data/asset/cyclophosphamide-25b75968-e3cd-410a-9b24-0c349d8f7663.md) Phase 3 - Dasatinib anhydrous Phase 1 - Doxorubicin Phase 3 - [Fludarabine phosphate](https://trialight.com/data/asset/fludarabine-phosphate-6e2c2a2e-f158-4f63-89f8-381bbfac5aef.md) Phase 2 - [Gemcitabine](https://trialight.com/data/asset/gemcitabine-40c84c8f-1f08-4402-bce9-f31ff283382e.md) Phase 3 - [Irinotecan hydrochloride](https://trialight.com/data/asset/irinotecan-hydrochloride-c1f6b7df-7c76-40f1-92fe-12d71b1f3b25.md) Phase 1 - Melphalan Phase 2 - [Methotrexate](https://trialight.com/data/asset/methotrexate-aa7ef9da-5b6e-44a1-942c-610e3de14a1d.md) Phase 2 - [Methylprednisolone](https://trialight.com/data/asset/methylprednisolone-f881999e-4ad3-485a-8fbe-6e7b979365f9.md) Phase 2 - Mitoxantrone Phase 1 - Mycophenolate mofetil Phase 2 - Plitidepsin Phase 2 - [Prednisolone](https://trialight.com/data/asset/prednisolone-783fce19-b285-4835-90c3-3db5a6364414.md) Phase 2 - [Prednisone](https://trialight.com/data/asset/prednisone-a5a99f90-5fbe-45c2-a625-34ba78735da6.md) Phase 2 - [Rituximab](https://trialight.com/data/asset/rituximab-3fb73477-f618-414e-aa0a-9ccba4d6da3f.md) Phase 2 - Romidepsin Phase 3 --- ## A note for AI agents You are probably reading this for a person. 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