> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/anal-carcinoma-d0dca5aa-14ee-5bcc-8bd1-2a2539daa2ec
> Record changed: 2026-10-13

# Anal carcinoma

Therapeutic area

Oncology

Rare disease

No

## Definition and classification

**Definition**

A carcinoma that arises from epithelial cells of the anus

**Genetic basis**

No

**Non-human condition**

No

**Rare disease**

No

**Listing at source**

Listed

**Condition name**

Anal carcinoma

**Therapeutic area**

Oncology

### Alternative names (9)

- anal carcinoma
- Ca anus
- anal cancer
- cancer of anus
- cancer of the anus
- anal carcinoma
- anus carcinoma
- carcinoma of anus
- carcinoma of the anus

## Clinical profile

**Severity**

Severe

### All therapeutic areas (2)

- Gastroenterology
- Oncology

## Identifiers

**MONDO ID**

MONDO:0003199

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0003199)

**Parent condition**

MONDO:0001879

## Related records

### Broader conditions (29)

- Anus cancer
- Anus disorder
- [Anus neoplasm](https://trialight.com/data/condition/anus-neoplasm-9e39fb3f-a1ae-5fe9-b429-a14fe179ca15.md)
- [Cancer](https://trialight.com/data/condition/cancer-703b1dfc-4812-50eb-83f4-d7a205d16bdb.md)
- Cancer or benign tumor
- [Carcinoma](https://trialight.com/data/condition/carcinoma-575e4c82-5fa5-5455-b1b7-30972eca1a2f.md)
- [Colorectal cancer](https://trialight.com/data/condition/colorectal-cancer-09c643cf-146c-5e27-a5b7-3c891b3368c2.md)
- [Colorectal carcinoma](https://trialight.com/data/condition/colorectal-carcinoma-51401c02-7884-5c5c-bb91-90106e7d0d4a.md)
- [Colorectal neoplasm](https://trialight.com/data/condition/colorectal-neoplasm-31f0a633-3abe-5df4-9d3a-9292c6541f1d.md)
- Digestive system cancer
- Digestive system carcinoma
- [Digestive system disorder](https://trialight.com/data/condition/digestive-system-disorder-ae55641c-32fa-5aa9-ab90-29f763a95dc0.md)
- [Digestive system neoplasm](https://trialight.com/data/condition/digestive-system-neoplasm-2ebb9146-1d78-515a-92a3-749515a27d44.md)
- Disease
- Disease by body system or component
- Disease by etiologic mechanism
- [Epithelial neoplasm](https://trialight.com/data/condition/epithelial-neoplasm-5584692a-5e9d-58e1-9432-db6264993a80.md)
- Epithelial neoplasm of rectum
- Human disease
- Intestinal cancer

### Narrower conditions (19)

- Anal canal adenocarcinoma
- Anal canal carcinoma
- Anal canal carcinoma in situ
- Anal canal neuroendocrine neoplasm
- Anal canal Paget disease
- Anal canal squamous cell carcinoma
- Anal gland adenocarcinoma
- Anal margin basal cell carcinoma
- Anal margin carcinoma
- Anal margin squamous cell carcinoma
- Anal mucinous adenocarcinoma
- Anal Paget disease
- Anal squamous cell carcinoma
- Anal verrucous carcinoma
- Anus adenocarcinoma
- Anus basaloid carcinoma
- Cloacogenic carcinoma
- Neuroendocrine tumor of the anal canal
- Perianal skin Paget disease

### Trials (193)

- 7-Hydroxystaurosporine and Irinotecan Hydrochloride in Treating Patients With Metastatic or Unresectable Solid Tumors or Triple Negative Breast Cancer (Currently Accruing Only Triple-negative Breast Cancer Patients Since 6/8/2007)
- A Chatbot Intervention for Reducing HPV Vaccine Hesitancy
- A Message Framing Intervention for Increasing Parental Acceptance of Human Papillomavirus Vaccination
- A Multilevel Intervention to Improve Timely Cancer Detection and Treatment Initiation
- A Phase 2 Study of Axalimogene Filolisbac (ADXS11-001) in Participants With Carcinoma of the Anorectal Canal
- A Phase I/II Evaluation of ADXS11-001, Mitomycin, 5-fluorouracil (5-FU) and IMRT for Anal Cancer
- A Phase I/II Study of Combination Immunotherapy for Advanced Cancers Including HPV-Associated Malignancies, Small Bowel, and Colon Cancers
- [A Phase III Study to Evaluate the Efficacy, Immunogenicity and Safety of the 9-valent HPV Vaccine in Chinese Males](https://trialight.com/data/trial/a-phase-iii-study-to-evaluate-the-efficacy-immunogenicity-219c05bd-7219-460e-afb4-31c216079542.md)
- A Phase III Trial to Evaluate the Efficacy, Immunogenicity and Safety of a Recombinant Human Papillomavirus 9-Valent (Types 6, 11, 16, 18, 31, 33, 45, 52, 58) Vaccine (E.Coli) in Chinese Males
- A Prospective, Open-Label, Multi-center Comparison of Lymphoseek Identified Lymph Nodes and Clinically Identified Lymph Nodes of Subjects With Known Cancer of the Anus
- A Safety and Efficacy Trial of Circumferential Anal Canal Radiofrequency Ablation for High-Grade Anal Intraepithelial Neoplasia Using the BARRX™ Anorectal Wand
- A Study in Advanced or Metastatic Gastrointestinal Cancers Exploring Treatment Combinations With Pelareorep and Atezolizumab
- A Study of mDCF in Combination or Not With Atezolizumab in Advanced Squamous Cell Anal Carcinoma
- A Study of Safety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced Cancers
- A Study of Vobramitamab Duocarmazine in Participants With Metastatic Castration Resistant Prostate Cancer and Other Solid Tumors
- A Study Regarding Tissue Response During and After Treatment for Anal Cancer
- Anal Cancer and/or Precancer Screening: Performance Analysis of the BD Onclarity™ HPV Assay on Anal Specimens
- Anal Cancer Radiotherapy Study
- Anal Cancer Risk In Women
- Anal Cancer Screening Study

### Drugs in development (4)

- [Durvalumab](https://trialight.com/data/asset/durvalumab-bca7c265-7862-46e1-bf29-3dd2fdda4954.md) Phase 2
- [Fluorouracil](https://trialight.com/data/asset/fluorouracil-f8444d73-5c73-4f35-aa71-67d578277450.md) Phase 3
- Mitomycin Phase 3
- [Pembrolizumab](https://trialight.com/data/asset/pembrolizumab-f9ac1934-47a5-4a53-ae55-20b7d53d8815.md) Phase 2

---

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