> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/alcohol-dependence-d26b3f0d-c0fb-5084-9194-e963df0e9179
> Record changed: 2026-10-13

# Alcohol dependence

Rare disease

No

## Definition and classification

**Definition**

Physical and psychological dependence on alcohol.

**Genetic basis**

Yes

**Non-human condition**

No

**Rare disease**

No

**Listing at source**

Listed

**Condition name**

Alcohol dependence

### Alternative names (3)

- alcohol dependence
- alcohol dependence
- alcoholism

## Clinical profile

**Severity**

Moderate

## Identifiers

**MONDO ID**

MONDO:0007079

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0007079)

**Parent condition**

MONDO:0005303

## Related records

### Broader conditions (8)

- Alcohol-related disorders
- Disease
- Disease by developmental or physiological process
- Drug dependence
- Human disease
- Psychiatric disorder
- Substance dependence
- [Substance-related disorder](https://trialight.com/data/condition/substance-related-disorder-9c15a305-edff-58d9-bcab-66e51bb69056.md)

### Trials (1,655)

- "ALCO-VR": Virtual Reality Cue Exposure Therapy for the Treatment of Alcohol Use Disorder
- "Juego de LLaves": Study Protocol of a Universal School-based Drug Use Prevention Program (PSIDUP)
- \[C-11\]NOP-1A and Alcohol Use Disorder
- \[C-11\]PiB PET Imaging in Alcohol Use Disorders
- 10 Days of Theta Burst Stimulation as a Tool to Treat Cocaine Dependence
- 12-step Facilitation for the Dually Diagnosed
- 90-Day Online Substance Use Program
- A Behavioral Activation Intervention Administered in a College Freshman Orientation Course
- A Clinical Trial on the Efficacy of tDCS) in Reducing Alcohol Consumption in Non-abstinent Patients (REDSTIM)
- A Clinical Trial to Assess Pharmacokinetic Profiles, Safety and Tolerability of IVL3004 and IVL4002 in Healthy Male Subjects.
- A Combined Neurofeedback-TMS Intervention for Alcohol Use Disorder
- A Community-Based Strategy for Preventing Underage Drinking
- A Comparison of Adolescent Group Therapy and Transitional Family Therapy for Adolescent Alcohol and Drug Abusers
- A Controlled Trial of Extended Brief Interventions in Alcohol Dependent Patients
- A Controlled Trial of Topiramate Treatment for Alcohol Dependence in Veterans With PTSD
- A Critical Illness Recovery Navigator for Alcohol
- A Dialectical Behavioral Therapy Digital Health Solution for Outpatients Seeking Support for Substance Use
- A Digital Pill System to Measure and Support Acamprosate Adherence in Individuals With Alcohol Associated Liver Disease
- A Dose-Escalation Study to Determine the Maximum Tolerated Dose of Arbaclofen Placarbil in Subjects With Alcohol Use Disorder
- A Double-Blind Trial of Psilocybin-Assisted Treatment of Alcohol Dependence

### Approved drugs (8)

- Acamprosate
- Acamprosate calcium
- Chlordiazepoxide
- Disulfiram
- Doxepin hydrochloride
- Nalmefene
- Nalmefene hydrochloride dihydrate
- Naltrexone

### Drugs in development (113)

- Acetylcarnitine Phase 1
- Acetylcysteine Phase 2
- [Alcohol](https://trialight.com/data/asset/alcohol-94acdb16-f595-4fd2-a9fa-0e1509bc9a8f.md) Phase 3
- Amitifadine Phase 2
- Apomorphine Phase 2
- [Apremilast](https://trialight.com/data/asset/apremilast-41723353-24b2-46d5-82cf-9e6280b6f765.md) Phase 2
- Aprepitant Phase 2
- Arbaclofen placarbil Phase 2
- [Aripiprazole](https://trialight.com/data/asset/aripiprazole-ca9997bd-e762-4bd5-ae57-3df4e68a30dd.md) Phase 3
- Aticaprant Phase 2
- Atomoxetine Phase 2
- Baclofen Phase 3
- Bavisant Phase 2
- Brexanolone Phase 1
- Brexpiprazole Phase 2
- Bupropion hydrochloride Phase 2
- Caffeine Phase 1
- Calcium carbimide Phase 2
- [Calcium carbonate](https://trialight.com/data/asset/calcium-carbonate-37e10d9b-34b0-4b9a-ad7f-b08adfd15b03.md) Phase 3
- Cannabidiol Phase 2

### Other linked drugs (9)

- Amperozide
- Chloral hydrate
- [Diazepam](https://trialight.com/data/asset/diazepam-a0cb3123-d888-4bf4-b90a-171c1dcecccb.md)
- Melperone
- Moxonidine
- Relacorilant
- Sulfasalazine
- Thiopental
- Tiapride

---

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