> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/aids-2a92a841-de6e-51af-bf3e-a52f5bafea66 > Record changed: 2026-11-04 # AIDS Therapeutic area Immunology Rare disease No ## Definition and classification **Definition** A syndrome resulting from the acquired deficiency of cellular immunity caused by the human immunodeficiency virus (HIV). It is characterized by the reduction of the Helper T-lymphocytes in the peripheral blood and the lymph nodes. Symptoms include generalized lymphadenopathy, fever, weight loss, and chronic diarrhea. Patients with AIDS are especially susceptible to opportunistic infections (usually pneumocystis carinii pneumonia, cytomegalovirus (CMV) infections, tuberculosis, candida infections, and cryptococcosis), and the development of malignant neoplasms (usually non-Hodgkin lymphoma and Kaposi sarcoma). The human immunodeficiency virus is transmitted through sexual contact, sharing of contaminated needles, or transfusion of contaminated blood. **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** AIDS **Therapeutic area** Immunology ### Alternative names (12) - AIDS - acquired immune deficiency - Acquired Immune Deficiency Syndrome - Acquired Immune Deficiency Syndrome (AIDS) - acquired immunodeficiency disease - Acquired Immunodeficiency Syndrome (AIDS) Virus - acquired immunodeficiency syndrome, AIDS - AIDS (Acquired Immune Deficiency Syndrome) - AIDS and Infections - AIDS, acquired immunodeficiency syndrome - Aids, Cdc Group I - aids, medication adherence ## Clinical profile **Severity** Severe ### Disease mechanisms (3) - Acquired - Genetic - Hereditary Sources for recorded values Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0012268) ### All therapeutic areas (3) - Immunology - Infectious Disease - Reproductive Health Sources for recorded values Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0012268) ## Identifiers **MONDO ID** MONDO:0012268 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0012268) **Parent condition** MONDO:0003780 ## Related records ### Broader conditions (18) - Disease - Disease by body system or component - Disease by etiologic mechanism - Disease of genetic or genomic mechanism - Disease of primarily extrinsic mechanism - [Hereditary disease](https://trialight.com/data/condition/hereditary-disease-df2f8f05-e0c9-5777-8e51-c3b6639743d3.md) - [HIV infectious disease](https://trialight.com/data/condition/hiv-infectious-disease-1260f28c-d667-55f9-b221-15d5017fde05.md) - Human disease - [Immune system disorder](https://trialight.com/data/condition/immune-system-disorder-24846188-b462-515c-bb34-142255a648c8.md) - Immunodeficiency disease - [Infectious disease](https://trialight.com/data/condition/infectious-disease-dadc2591-65fc-5842-b510-cfbc295d8093.md) - Lentivirus infection - Primary viral infectious disease - Reproductive system disorder - Sexually transmitted disease - T-cell immunodeficiency - [Viral infectious disease](https://trialight.com/data/condition/viral-infectious-disease-43db42a3-adad-5b9d-b74c-f17df0674c21.md) - Viral sexually transmitted disease ### Trials (3,038) - 'Activity Pacing' in PLWH With Fatigue Symptoms. - 'HI-4-TU' Study: Health Improvement for Teen Ugandans Study - "OK 2004 Study" (Only Kaletra 2004 Study): Study to Evaluate Suspending Nucleosides From Triple-Drug Therapy in HIV Subjects - "Switch Either Near Suppression Or THOusand" - (Ro 24-2027) A Randomized, Double-Blind, Comparative Study of Dideoxycytidine (ddC) Versus Zidovudine (AZT) in Patients With AIDS or Advanced ARC - #AWARE.HIV Europe: Supporting Healthcare Professionals to Find Undiagnosed HIV in European Hospitals: An Effectiveness-implementation Trial. - 123I Radiolabeled 3BNC117 - 2-5 Intermittent Caloric Restriction in HIV - 2-stage Cervical Cancer Screening in Botswana - 2nd AC+: New Village Model - 2NN & CHARM Long-Term Follow-up Study - 3BNC117 and 10-1074 in ART-treated Individuals - 3BNC117 and 10-1074 in HIV Uninfected Adults - 3BNC117 and 10-1074 in HIV-infected Individuals - 3BNC117-LS and 10-1074-LS in Viremic HIV-infected Individuals - 3BNC117-LS and 10-1074-LS Plus N-803 (bNAb+N-803) - 3BNC117-LS First-in-Human Phase 1 Study - 3TC (Lamivudine; GR109714X) Open-Label Program - 4-Methylumbelliferone as a Treatment for Chronic HBV/HCV - 90 DAYS: An Entertainment Education Intervention to Evaluate a Short Film About HIV Status Disclosure ### Approved drugs (4) - Ganciclovir sodium - Lexgenleucel-T - [Megestrol acetate](https://trialight.com/data/asset/megestrol-acetate-d15299dc-52b5-4b77-a983-b7a643fb06ca.md) - Valganciclovir hydrochloride ### Drugs in development (122) - 9-aminocamptothecin Phase 2 - Abacavir Phase 3 - Acetylcysteine Phase 2 - Albuvirtide Phase 3 - Aldesleukin Phase 1 - Ammonium trichlorotellurate Phase 1 - Amphotericin B Phase 3 - Amprenavir Phase 1 - Arsenic trioxide Phase 1 - Atazanavir Phase 3 - Bictegravir sodium Phase 3 - Bleomycin Phase 3 - Bleomycin sulfate Phase 1 - [Bortezomib](https://trialight.com/data/asset/bortezomib-35a853cf-26ab-4a4c-a405-ae671d364aad.md) Phase 1 - Busulfan Phase 1 - Cannabinol Phase 2 - Carbomer homopolymer type B (allyl pentaerythritol crosslinked) Phase 1 - [Chloroquine](https://trialight.com/data/asset/chloroquine-60719e05-c0d4-438d-9681-2c553d6d6e4d.md) Phase 2 - Cholecalciferol Phase 2 - Cidofovir Phase 2 ### Other linked drugs (17) - [Acetaminophen](https://trialight.com/data/asset/acetaminophen-04ea33a5-49ee-4a1b-ad16-54627012140e.md) - Alovudine - [Atezolizumab](https://trialight.com/data/asset/atezolizumab-2cce6944-73b7-49f4-8125-4e6747997b82.md) - [Clindamycin](https://trialight.com/data/asset/clindamycin-a5de7244-d524-4d80-bc8e-abc6aae0bdab.md) - CO-trimoxazole - Crofelemer - Darbepoetin alfa - Dinitrochlorobenzene - Disulfiram - Ditiocarb sodium - Epoetin beta - Fosamprenavir sodium - Inosine pranobex - [Leucovorin calcium](https://trialight.com/data/asset/leucovorin-calcium-8da292ca-1b92-4365-b525-77d897b1c096.md) - Methadone - Primaquine - Pyrimethamine --- ## A note for AI agents You are probably reading this for a person. 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