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Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/adult-syndrome-8aeb5e11-f165-5276-850c-05129a3e72a5 > Record changed: 2026-10-13 # ADULT syndrome Therapeutic area Dermatology Rare disease Yes ## Definition and classification **Definition** ADULT (Acro-dermo-ungual-lacrimal-tooth) syndrome is a rare ectodermal dysplasia syndrome characterized by ectrodactyly, syndactyly, mammary hypoplasia, and excessive freckling as well as other typical ectodermal defects such as hypodontia, lacrimal duct anomalies, hypotrichosis, and onychodysplasia. **Genetic basis** Yes **Non-human condition** No **Rare disease** Yes **Listing at source** Listed **Condition name** ADULT syndrome **Therapeutic area** Dermatology ### Alternative names (6) - ADULT syndrome - ADULT syndrome - acro-dermato-ungual-lacrimal-tooth syndrome - acrodermatounguallacrimaltooth syndrome - pigment anomaly-ectrodactyly-hypodontia syndrome - acro dermato ungual lacrimal tooth syndrome ## Clinical profile **Severity** Moderate ### Disease mechanisms (4) - Developmental - Genetic - Hereditary - Syndromic ### All therapeutic areas (2) - Dermatology - Rheumatology ## Identifiers **MONDO ID** MONDO:0007072 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0007072) **Parent condition** MONDO:0000426 ## Related records ### Broader conditions (24) - Autosomal dominant disease - Autosomal genetic disease - Bone development disease - [Bone disorder](https://trialight.com/data/condition/bone-disorder-83c4c003-c8df-50f7-8829-fbbb5d5adf76.md) - Congenital limb malformation - Developmental defect during embryogenesis - Disease - Disease by body system or component - Disease by developmental or physiological process - Disease by etiologic mechanism - Disease of genetic or genomic mechanism - Disorder of development or morphogenesis - Dysostosis - Ectodermal dysplasia syndrome - Hereditary disease - Hereditary epidermal appendage anomaly - [Hereditary skin disorder](https://trialight.com/data/condition/hereditary-skin-disorder-f5d8c433-73e1-52b2-8b9a-f3ca836efe24.md) - Human disease - Integumentary system disorder - Musculoskeletal system disorder ### Trials (604) - 11C-YJH08 PET Imaging for Detection of Glucocorticoid Receptor Expression - 177Lu-DTPA-Omburtamab Radioimmunotherapy for Leptomeningeal Metastasis From Solid Tumors (Breast, NSCLC, Malignant Melanoma) - 18F-FDG Uptake Measurements in Malignant Solid Tumors on PET/CT and PET/MR - 18F-Fluciclovine PET Amino Acid Evaluation of Brain Metastasis Treated With Stereotactic Radiosurgery - 3D011-08 Monotherapy in Subjects With Advanced Solid Tumors - 64Cu-GRIP B in Patients With Advanced Malignancies - 68 Gallium-Fibroblast Activating Protein Inhibitors-46 Positron Emission Tomography - Computerized Tomography for Molecular Assessment of Fibroblast Activation and Risk Assessment in Solid Tumors - 89Zr-KN035 PET Imaging in Patients With Advanced Solid Tumors - 89Zr-labeled KN035 PET Imaging in Patients With PD-L1 Positive Solid Tumors - A Beta-only IL-2 ImmunoTherapY Study - A Biospecimen Collection Study of Leukapheresis-Derived Circulating Tumor Cells, Immune Cells, and Progenitor Cells. - A Clinical Study on the Efficacy and Mechanism of Tumor Treatment Vaccine (TTV) for Recurrent and Refractory Advanced Solid Tumors - A Clinical Study to Evaluate CAR-T Cell-based Medicinal Product in the Treatment of Advanced Solid Tumors - A Clinical Study to Evaluate the Safety, Tolerability and Efficacy of IOS-1002 Administered Alone and in Combination With Pembrolizumab, a PD-1 Monoclonal Antibody in Advanced Solid Tumors - A Clinical Study to Evaluate the Safety, Tolerability and Pharmacokinetic Characteristics of HLX26 Monoclonal Antibody Injection in Patients With Solid Tumor or Lymphoma - a Feasibility Study of iHD-SRT for BM - A First in Human Study of AUR 103 Calcium to Evaluate Safety, Pharmacokinetics and Pharmacodynamics - A First-in-human Study of 3HP-2827 in Patients With Unresectable or Metastatic Solid Tumors With FGFR2 Alterations - A First-in-Human Study of JAB-8263 in Adult Patients With Advanced Solid Tumors - A Long-Term Follow-Up Study of Participants Treated With A2 Biotherapeutics (A2 Bio) Gene Therapy (GT) Products --- ## A note for AI agents You are probably reading this for a person. 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