> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/acute-respiratory-failure-a4d08df7-7f5c-558c-9da0-305072fe16fe
> Record changed: 2026-10-13

# Acute respiratory failure

Therapeutic area

Pulmonology

Rare disease

No

## Definition and classification

**Definition**

Life-threatening respiratory failure that develops rapidly. Causes include injury, sepsis, drug overdose, and pancreatitis. It manifests with dyspnea and cyanosis and may lead to cardiovascular shock.

**Genetic basis**

No

**Non-human condition**

No

**Rare disease**

No

**Listing at source**

Listed

**Condition name**

Acute respiratory failure

**Therapeutic area**

Pulmonology

### Alternative names (3)

- acute respiratory failure
- acute respiratory failure
- respiratory failure, acute

## Clinical profile

**All therapeutic areas**

- Pulmonology

**Severity**

Severe

## Identifiers

**MONDO ID**

MONDO:0001208

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0001208)

**Parent condition**

MONDO:0020683

## Related records

### Broader conditions (8)

- Acute disease
- Disease
- Disease by body system or component
- Human disease
- [Lower respiratory tract disorder](https://trialight.com/data/condition/lower-respiratory-tract-disorder-cfa96f5e-8af8-555b-a663-55befbd68962.md)
- [Lung disorder](https://trialight.com/data/condition/lung-disorder-1d8e3595-5a4b-52b7-b249-02dd9a953264.md)
- Respiratory failure
- Respiratory system disorder

### Narrower conditions (8)

- [Acute respiratory distress syndrome](https://trialight.com/data/condition/acute-respiratory-distress-syndrome-8dc4b74c-8356-5dfd-bfa3-258d9d1e44ab.md)
- [Adult acute respiratory distress syndrome](https://trialight.com/data/condition/adult-acute-respiratory-distress-syndrome-52101d99-65d3-54cf-b5da-f664febc6a7e.md)
- High altitude pulmonary edema
- Neonatal respiratory failure
- [Newborn respiratory distress syndrome](https://trialight.com/data/condition/newborn-respiratory-distress-syndrome-09475735-1d09-548f-9261-b73619bb9db3.md)
- Pediatric acute respiratory distress syndrome
- Pulmonary edema
- Respiratory distress syndrome in premature infants

### Trials (287)

- "VARIABLE-PSV" Study
- A Check-list Including Lung Ultrasound for ED Patients With ARF
- A Clinical Study for Developing Artificial Intelligence(AI)-Based Clustering Model for Personalized Medicine in Acute Respiratory Failure
- A Pilot Study of Combined Cycle Ergometry and Amino Acids in the ICU
- A Prospective Observational Cohort Study of Awake Prone Position Ventilation Strategy in Patients With Acute Respiratory Failure
- A Randomised Controlled Trial of High-Flow Nasal Oxygen Versus Standard Oxygen Therapy in Critically Ill Immunocompromised Patients
- A Study of Communication Between Clinicians, Patients, and Families in the Intensive Care Unit (ICU)
- Acute DYSPnea in the Emergency Department: Diagnostic Value of Point-of-care UltraSound
- Adjusted Ventilatory Assist (NAVA-NIV) in Infants: Short-term Physiological Study
- Advanced Respiratory Monitoring and Oxygen Therapy in Chronically Ill Patients With Acute Respiratory Failure
- Airway Inflammatory Response During Illness in Children With Respiratory Failure
- AKI Biomarkers in Coronavirus(COVID)-19
- ARrest RESpiraTory Failure From PNEUMONIA
- Assessing Ventilator Safety in Patients on Pressure-Support Ventilation
- Assessment of Ventilation Parameters for Extubation Prediction in ICU
- Asymmetric High-flow Nasal Cannula (HFNC) vs Standard HFNC for Post Extubation High-risk Group
- Bed Side Assessment in Patients With Acute Respiratory Failure Under Invasive Mechanical Ventilation
- BELLRICU PROJECT: Precision Medicine in Respiratory Intermediate Care Units
- Better Arterial Cannulation Technique With Different Hemodynamics
- Bivalirudin Versus Enoxaparin in Critically Ill COVID-19 Patients

### Drugs in development (3)

- Amino acids Phase 2
- Dexmedetomidine Phase 2
- [Tozorakimab](https://trialight.com/data/asset/tozorakimab-2f585124-3232-4184-a7a4-ad2b7db2f5dd.md) Phase 3

### Other linked drugs (2)

- Ketamine
- Thiamine

---

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