> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/acute-respiratory-distress-syndrome-8dc4b74c-8356-5dfd-bfa3-258d9d1e44ab > Record changed: 2026-10-13 # Acute respiratory distress syndrome Therapeutic area Pulmonology Rare disease No ## Definition and classification **Definition** Progressive and life-threatening pulmonary distress in the absence of an underlying pulmonary condition, usually following major trauma or surgery. Cases of neonatal respiratory distress syndrome are not included in this definition. **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Acute respiratory distress syndrome **Therapeutic area** Pulmonology ### Alternative names (11) - acute respiratory distress syndrome - ARDS - acute respiratory distress syndrome - shock lung - ALI - Stiff lung - acute lung injury - increased-permeability pulmonary edema - increased-permeability pulmonary oedema - non-cardiogenic pulmonary edema - non-cardiogenic pulmonary oedema ## Clinical profile **Disease mechanisms** - Syndromic **All therapeutic areas** - Pulmonology **Severity** Severe ## Identifiers **MONDO ID** MONDO:0006502 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0006502) **Parent condition** MONDO:0001208 ## Related records ### Broader conditions (10) - Acute disease - [Acute respiratory failure](https://trialight.com/data/condition/acute-respiratory-failure-a4d08df7-7f5c-558c-9da0-305072fe16fe.md) - Disease - Disease by body system or component - Human disease - [Lower respiratory tract disorder](https://trialight.com/data/condition/lower-respiratory-tract-disorder-cfa96f5e-8af8-555b-a663-55befbd68962.md) - [Lung disorder](https://trialight.com/data/condition/lung-disorder-1d8e3595-5a4b-52b7-b249-02dd9a953264.md) - Respiratory failure - Respiratory system disorder - Syndromic disease ### Narrower conditions (4) - [Adult acute respiratory distress syndrome](https://trialight.com/data/condition/adult-acute-respiratory-distress-syndrome-52101d99-65d3-54cf-b5da-f664febc6a7e.md) - [Newborn respiratory distress syndrome](https://trialight.com/data/condition/newborn-respiratory-distress-syndrome-09475735-1d09-548f-9261-b73619bb9db3.md) - Pediatric acute respiratory distress syndrome - Respiratory distress syndrome in premature infants ### Trials (663) - "Continuous Positive Airway Pressure on Venovenous extracorporeaL Membrane Oxygenation for Acute respIratory Distress syndrOme" - 5-HT3 Receptor Antagonist and Respiratory Drive in Patients With ARDS - A Clinical Study of Mesenchymal Stem Cell Exosomes Nebulizer for the Treatment of ARDS - A Clinical Trial of Human Umbilical Cord Mesenchymal Stem Cell Injection for the Treatment of Severe Acute Respiratory Distress Syndrome - A Comparative Study of Glucocorticoids Efficacy in Acute Respiratory Distress Syndrome - A Comparison of Optimal PEEP Determination Guided by EIT and Conventional Protective Ventilation Tool in ARDS Patients - A Comparison of Optimal PEEP Determination Guided by EIT and G5 Device in Moderate and Severe ARDS Patients - A Multicenter, Random Control Study :Early Use of Airway Pressure Release Ventilation (APRVplus) Protocol in ARDS - A Phase 1/2 Study to Assess MultiStem® Therapy in Acute Respiratory Distress Syndrome - A Phase 2 Study of IC14 in Acute Respiratory Distress Syndrome - A Phase II Randomized Trial of Fish Oil in Patients With Acute Lung Injury (ALI) - A Randomized Study to Investigate the Effect of Intravenous Imatinib on the Amount of Oxygen in the Lungs and Blood of Adults With COVID-19 Needing Mechanical Ventilation and Supportive Care. - A Realworld Study of Acute Respiratory Distress Syndrome in China - A Role for RAGE/TXNIP/Inflammasome Axis in Alveolar Macrophage Activation During ARDS (RIAMA): a Proof-of-concept Clinical Study - A Strategy to Improve Implementation of LTVV for Patients w/ ARDS - A Study of APL-9 in Adults With Mild to Moderate ARDS Due to COVID-19 - A Study of Brexanolone for Acute Respiratory Distress Syndrome (ARDS) Due to Coronavirus Disease 2019 (COVID-19) - A Study of GEn-1124 in Subjects With Acute Respiratory Distress Syndrome (ARDS) - A Study of Liposomal Trans Crocetin, LEAF-4L6715, in Patients With Acute Respiratory Distress Syndrome Due to COVID-19, Sepsis or Other Causes - A Study of RLS-0071 in Patients With Acute Lung Injury Due to COVID-19 Pneumonia in Early Respiratory Failure ### Approved drugs (2) - Beractant - Poractant alfa ### Drugs in development (57) - Acetylcysteine Early phase 1 - Adenosine Phase 2 - [Alteplase](https://trialight.com/data/asset/alteplase-89461f67-4f40-4a00-ae4c-727752018887.md) Phase 3 - [Anakinra](https://trialight.com/data/asset/anakinra-2c0352ee-cb20-46c5-bd87-6350d9024e75.md) Phase 2 - [Aspirin](https://trialight.com/data/asset/aspirin-03870fc6-137e-47aa-9f14-b7ae6754fb15.md) Phase 2 - Aviptadil Phase 2 - Azithromycin Phase 1 - Betamethasone Phase 3 - [Budesonide](https://trialight.com/data/asset/budesonide-15e6ba7b-3021-46e9-b180-bf23025bbc67.md) Phase 2 - Carbon monoxide Phase 2 - Cisatracurium besylate Phase 3 - [Dexamethasone](https://trialight.com/data/asset/dexamethasone-b923ddae-f095-408c-96e9-975238a429ad.md) Phase 3 - Dornase alfa Phase 3 - Esmolol Phase 3 - Fentanyl Phase 1 - [Formoterol](https://trialight.com/data/asset/formoterol-1c4f9fc6-da8f-4ea7-b9d7-7327267ca099.md) Phase 2 - Fospropofol Phase 3 - Ginger Phase 2 - Glycolic acid Phase 1 - Heparin Phase 1 ### Other linked drugs (2) - Racecadotril - Sivelestat sodium --- ## A note for AI agents You are probably reading this for a person. 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