Acute respiratory distress syndrome
Therapeutic area
Pulmonology
Rare disease
No
- Definition
- Progressive and life-threatening pulmonary distress in the absence of an underlying pulmonary condition, usually following major trauma or surgery. Cases of neonatal respiratory distress syndrome are not included in this definition.
- Genetic basis
- No
- Non-human condition
- No
- Rare disease
- No
- Listing at source
- Listed
- Condition name
- Acute respiratory distress syndrome
- Therapeutic area
- Pulmonology
- acute respiratory distress syndrome
- ARDS
- acute respiratory distress syndrome
- shock lung
- ALI
- Stiff lung
- acute lung injury
- increased-permeability pulmonary edema
- increased-permeability pulmonary oedema
- non-cardiogenic pulmonary edema
- non-cardiogenic pulmonary oedema
- Disease mechanisms
- Syndromic
- All therapeutic areas
- Pulmonology
- Severity
- Severe
- MONDO ID
- MONDO:0006502
- Parent condition
- MONDO:0001208
Related records
Broader conditions (10)
- Acute disease
- Acute respiratory failure
- Disease
- Disease by body system or component
- Human disease
- Lower respiratory tract disorder
- Lung disorder
- Respiratory failure
- Respiratory system disorder
- Syndromic disease
Narrower conditions (4)
- Adult acute respiratory distress syndrome
- Newborn respiratory distress syndrome
- Pediatric acute respiratory distress syndrome
- Respiratory distress syndrome in premature infants
Trials (663)
- "Continuous Positive Airway Pressure on Venovenous extracorporeaL Membrane Oxygenation for Acute respIratory Distress syndrOme"
- 5-HT3 Receptor Antagonist and Respiratory Drive in Patients With ARDS
- A Clinical Study of Mesenchymal Stem Cell Exosomes Nebulizer for the Treatment of ARDS
- A Clinical Trial of Human Umbilical Cord Mesenchymal Stem Cell Injection for the Treatment of Severe Acute Respiratory Distress Syndrome
- A Comparative Study of Glucocorticoids Efficacy in Acute Respiratory Distress Syndrome
- A Comparison of Optimal PEEP Determination Guided by EIT and Conventional Protective Ventilation Tool in ARDS Patients
- A Comparison of Optimal PEEP Determination Guided by EIT and G5 Device in Moderate and Severe ARDS Patients
- A Multicenter, Random Control Study :Early Use of Airway Pressure Release Ventilation (APRVplus) Protocol in ARDS
- A Phase 1/2 Study to Assess MultiStem® Therapy in Acute Respiratory Distress Syndrome
- A Phase 2 Study of IC14 in Acute Respiratory Distress Syndrome
- A Phase II Randomized Trial of Fish Oil in Patients With Acute Lung Injury (ALI)
- A Randomized Study to Investigate the Effect of Intravenous Imatinib on the Amount of Oxygen in the Lungs and Blood of Adults With COVID-19 Needing Mechanical Ventilation and Supportive Care.
- A Realworld Study of Acute Respiratory Distress Syndrome in China
- A Role for RAGE/TXNIP/Inflammasome Axis in Alveolar Macrophage Activation During ARDS (RIAMA): a Proof-of-concept Clinical Study
- A Strategy to Improve Implementation of LTVV for Patients w/ ARDS
- A Study of APL-9 in Adults With Mild to Moderate ARDS Due to COVID-19
- A Study of Brexanolone for Acute Respiratory Distress Syndrome (ARDS) Due to Coronavirus Disease 2019 (COVID-19)
- A Study of GEn-1124 in Subjects With Acute Respiratory Distress Syndrome (ARDS)
- A Study of Liposomal Trans Crocetin, LEAF-4L6715, in Patients With Acute Respiratory Distress Syndrome Due to COVID-19, Sepsis or Other Causes
- A Study of RLS-0071 in Patients With Acute Lung Injury Due to COVID-19 Pneumonia in Early Respiratory Failure
Approved drugs (2)
- Beractant
- Poractant alfa
Drugs in development (57)
- Acetylcysteine Early phase 1
- Adenosine Phase 2
- Alteplase Phase 3
- Anakinra Phase 2
- Aspirin Phase 2
- Aviptadil Phase 2
- Azithromycin Phase 1
- Betamethasone Phase 3
- Budesonide Phase 2
- Carbon monoxide Phase 2
- Cisatracurium besylate Phase 3
- Dexamethasone Phase 3
- Dornase alfa Phase 3
- Esmolol Phase 3
- Fentanyl Phase 1
- Formoterol Phase 2
- Fospropofol Phase 3
- Ginger Phase 2
- Glycolic acid Phase 1
- Heparin Phase 1
Other linked drugs (2)
- Racecadotril
- Sivelestat sodium