> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/acute-myocardial-infarction-da0938fb-d3f9-529e-8fe5-160ac87e5b7a
> Record changed: 2026-10-13

# Acute myocardial infarction

Therapeutic area

Cardiology

Rare disease

No

## Definition and classification

**Definition**

Necrosis of the myocardium, as a result of interruption of the blood supply to the area. It is characterized by a severe and rapid onset of symptoms that may include chest pain, often radiating to the left arm and left side of the neck, dyspnea, sweating, and palpitations.

**Genetic basis**

No

**Non-human condition**

No

**Rare disease**

No

**Listing at source**

Listed

**Condition name**

Acute myocardial infarction

**Therapeutic area**

Cardiology

### Alternative names (3)

- acute myocardial infarction
- acute myocardial infarction (disease)
- myocardial infarction (disease), acute

## Clinical profile

**All therapeutic areas**

- Cardiology

**Severity**

Severe

## Identifiers

**MONDO ID**

MONDO:0004781

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0004781)

**Parent condition**

MONDO:0005068

## Related records

### Broader conditions (8)

- Acute disease
- [Cardiovascular disorder](https://trialight.com/data/condition/cardiovascular-disorder-362e433e-88a4-575f-90af-50fe7239dec0.md)
- Disease
- Disease by body system or component
- Heart disorder
- Human disease
- Myocardial disorder
- [Myocardial infarction](https://trialight.com/data/condition/myocardial-infarction-b4e97483-7435-5701-81dc-26d955e420ec.md)

### Narrower conditions (6)

- Acute anterolateral myocardial infarction
- Acute inferolateral myocardial infarction
- Acute inferoposterior infarction
- Acute subendocardial myocardial infarction
- [ST-elevation myocardial infarction](https://trialight.com/data/condition/st-elevation-myocardial-infarction-4462ec3a-15ca-527b-a581-39887b4bda63.md)
- Strictly posterior acute myocardial infarction

### Trials (668)

- "ESTIMATION Study" for Endocardial Mesenchymal Stem Cells Implantation in Patients After Acute Myocardial Infarction
- 68 Ga-NODAGA-E\[c(RGDγK)\]2: Positron Emission Tomography Tracer for Imaging of Myocardial Angiogenesis
- A Behavioral Economics-Based Telehealth Intervention to Improve Post-MI Medication Adherence
- A Case-control Study of Costa Rican Adults With Myocardial Infarction
- A Clinical Cohort Registry Study on Primary PCI for Acute Myocardial Infarction at Zhongshan Hospital
- A Comparison of p53-induced Genes Activation in Patients With and Without Acute Myocardial Infarction
- A Danish ICD-study in Patients with Coronary Artery Disease Resuscitated from Ventricular Fibrillation
- A Medical Research Study to Evaluate the Effects of ACT-246475 in Adults With Heart Attack
- A Multicentre Observational Study to Assess Long-term Outcome of Participants in the EXCELLENT Clinical Trial
- A Phase 2b Study of CSL112 in Subjects With Acute Myocardial Infarction.
- A Phase I - II Safety Study of Filgrastim (Neupogen) to Improve Left Ventricular Function After Severe Acute Myocardial Infarction
- A Pilot Study of Transcoronary Myocardial Cooling
- A Polypill for Secondary Prevention of Ischemic Heart Disease
- A Registry Study on Genetics and Biomarkers of Acute Coronary Syndrome
- A Safety/Efficacy Study of Intra-coronary Tenecteplase During Balloon Angioplasty to Treat Heart Attacks
- A Study of Acute Myocardial Infarction Using FDY-5301
- A Study of CSL112 in Adults With Moderate Renal Impairment and Acute Myocardial Infarction
- A Study of CSL112 in Healthy Adults and in Adults With Moderate Renal Impairment
- A Study of INO-1001, an Intravenous PARP (Poly \[ADP Ribose\] Polymerase) Inhibitor in Acute Heart Attack Patients Undergoing Primary Percutaneous Coronary Intervention
- A Study of the Safety and Efficacy of Injectable Thymosin Beta 4 for Treating Acute Myocardial Infarction

### Approved drugs (9)

- [Aspirin](https://trialight.com/data/asset/aspirin-03870fc6-137e-47aa-9f14-b7ae6754fb15.md)
- Atorvastatin calcium
- [Enoxaparin sodium](https://trialight.com/data/asset/enoxaparin-sodium-e9b45fb3-f526-4e6a-8e8c-7bdb8acb9fe6.md)
- Eptifibatide
- Ramipril
- Simvastatin
- [Tenecteplase](https://trialight.com/data/asset/tenecteplase-01f5448a-c2ca-4332-92f6-1d9ef8a99284.md)
- Ticagrelor
- [Valsartan](https://trialight.com/data/asset/valsartan-8c0ec3b4-e04a-4ab5-a1ce-08db104f46b9.md)

### Drugs in development (47)

- .ALPHA.1-proteinase inhibitor human Phase 1
- Abciximab Phase 3
- Acetylcysteine Phase 3
- Adenosine Phase 3
- [Anakinra](https://trialight.com/data/asset/anakinra-2c0352ee-cb20-46c5-bd87-6350d9024e75.md) Phase 3
- Bivalirudin Phase 3
- Clopidogrel Phase 3
- Cyclosporine Phase 3
- Darbepoetin alfa Phase 3
- [Deferiprone](https://trialight.com/data/asset/deferiprone-de409404-552d-4d3b-8bc1-4703695fba59.md) Phase 1
- Edoxaban Phase 2
- Elamipretide hydrochloride Phase 2
- [Empagliflozin](https://trialight.com/data/asset/empagliflozin-09301932-ac0f-4eb7-8d1d-bd13fdbb6ab8.md) Phase 3
- Epoetin beta Phase 3
- Ethylene Phase 2
- Exenatide Phase 3
- [Filgrastim](https://trialight.com/data/asset/filgrastim-942bf0d3-0bf1-4bf8-9e38-81a6c277d728.md) Phase 3
- Furosemide Phase 3
- Gelatin Phase 2
- Heme arginate Phase 1

### Other linked drugs (5)

- [Acetaminophen](https://trialight.com/data/asset/acetaminophen-04ea33a5-49ee-4a1b-ad16-54627012140e.md)
- Atorvastatin
- Delcasertib
- Nicorandil
- Ridogrel

---

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