> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/acute-lung-injury-fb11c447-d7f6-5c24-8fb9-764bbaaabced > Record changed: 2026-10-13 # Acute lung injury Therapeutic area Pulmonology Rare disease Yes ## Definition and classification **Definition** A condition of lung damage that is characterized by bilateral pulmonary infiltrates (pulmonary edema) rich in neutrophils, and in the absence of clinical heart failure. This can represent a spectrum of pulmonary lesions, endothelial and epithelial, due to numerous factors (physical, chemical, or biological). **Genetic basis** No **Non-human condition** No **Rare disease** Yes **Listing at source** Listed **Condition name** Acute lung injury **Alternative names** - acute lung injury **Therapeutic area** Pulmonology ## Clinical profile **All therapeutic areas** - Pulmonology **Severity** Severe ## Identifiers **MONDO ID** MONDO:0015796 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0015796) **Parent condition** MONDO:0005275 ## Related records ### Broader conditions (8) - Acute disease - Disease - Disease by body system or component - Human disease - Injury - [Lower respiratory tract disorder](https://trialight.com/data/condition/lower-respiratory-tract-disorder-cfa96f5e-8af8-555b-a663-55befbd68962.md) - [Lung disorder](https://trialight.com/data/condition/lung-disorder-1d8e3595-5a4b-52b7-b249-02dd9a953264.md) - Respiratory system disorder ### Trials (377) - A Phase II Randomized Trial of Fish Oil in Patients With Acute Lung Injury (ALI) - A Phase II Study to Determine the Efficacy and Safety of Sivelestat in Subjects With Acute Lung Injury - A Pilot Study Using Placenta Derived Decidual Stromal Cells for Toxicity and Inflammation With Special Focus to the Allogeneic Hematopoietic Cell Transplantation Setting - A Real World Study of Respiratory Critical Disease. - A Reverification of the Berlin Definition Plateau Criteria in Golmud - A Single Dose, Dose Escalation Clinical Trial on the Safety, Tolerability and Efficacy of Lyophilized Powder for Inhalation of Recombinant Human Keratinocyte Growth Factor-2 (Rh-KGF-2) in The Treatment of Patients With Acute Respiratory Distress Syndrome - a Study Conducted About a New Mode of Ventilation in Laparoscopic Surgeries - A Study of APL-9 in Adults With Mild to Moderate ARDS Due to COVID-19 - A Study of RLS-0071 in Patients With Acute Lung Injury Due to COVID-19 Pneumonia in Early Respiratory Failure - A Study on the Treatment of Patients With Acute Lung Injury Caused by Sepsis Through Microbiota Transplantation - A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of an Intravenous Infusion of GW328267X in Healthy Volunteers - A Study to Investigate the Effects of Imatinib on Pulmonary Vascular Dysfunction in a Human Model of Lung Injury - A Trial to Evaluate the Impact of Lung-protective Intervention in Patients Undergoing Esophageal Cancer Surgery - Acute CorPulmonale and ARDS Circulation Protection China Study China (ACPC) - Acute Lung Injury After Allogeneic Transplantation - Diagnosis and Early Treatment - Acute Lung Injury After Cardiac Surgery: Pathogenesis - Acute Lung Injury in Children: Epidemiology and Natural History. PEDIATRIC ALIEN. - Acute Lung Injury Ventilator Evaluation (ALIVE) - Administration of Intravenous Vitamin C in Novel Coronavirus Infection (COVID-19) and Decreased Oxygenation - Adrecizumab (HAM8101) to Improve Prognosis and Outcomes in COVID-19 Trial ### Drugs in development (28) - Acetylcysteine Phase 2 - Ascorbic acid Phase 2 - [Aspirin](https://trialight.com/data/asset/aspirin-03870fc6-137e-47aa-9f14-b7ae6754fb15.md) Phase 2 - Aviptadil Phase 2 - Calfactant Phase 2 - Daxdilimab Phase 1 - Depelestat Phase 2 - Dilmapimod Phase 2 - Dobutamine Phase 2 - Epinephrine Phase 2 - Furosemide Phase 2 - GSK-2586881 Phase 2 - GW-328267 Phase 1 - Heparin Phase 3 - Imatinib Phase 1 - L-citrulline Phase 3 - Lactose, anhydrous Phase 2 - Nezulcitinib Phase 1 - Norepinephrine Phase 2 - Phenylephrine Phase 2 ### Other linked drugs (4) - Ivacaftor - Lumacaftor - [Tezacaftor](https://trialight.com/data/asset/tezacaftor-361d103a-bfda-4757-93c8-8092efda7716.md) - [Xenon](https://trialight.com/data/asset/xenon-823d22f5-381f-43f8-8ee3-f91ebdb28f1c.md) --- ## A note for AI agents You are probably reading this for a person. 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