> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/acute-coronary-syndrome-3d7c2c1f-86ca-5a25-913a-6f9a7e95f989 > Record changed: 2026-10-13 # Acute coronary syndrome Therapeutic area Cardiology Rare disease No ## Definition and classification **Definition** Signs and symptoms related to acute ischemia of the myocardium secondary to coronary artery disease. The clinical presentation covers a spectrum of heart diseases from unstable angina to myocardial infarction. **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Acute coronary syndrome **Therapeutic area** Cardiology ### Alternative names (7) - acute coronary syndrome - acute coronary syndrome - acute coronary syndromes - coronary syndrome, acute - coronary syndromes, acute - syndrome, acute coronary - syndromes, acute coronary ## Clinical profile **Disease mechanisms** - Syndromic **Severity** Severe ### All therapeutic areas (2) - Cardiology - Vascular Medicine ## Identifiers **MONDO ID** MONDO:0005542 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005542) **Parent condition** MONDO:0002254 ## Related records ### Broader conditions (11) - Acute disease - [Cardiovascular disorder](https://trialight.com/data/condition/cardiovascular-disorder-362e433e-88a4-575f-90af-50fe7239dec0.md) - Disease - Disease by body system or component - Heart disorder - Human disease - Ischemic disease - Myocardial disorder - Myocardial ischemia - Syndromic disease - Vascular disorder ### Trials (1,444) - 'MInimalist' or 'MOre Complete' Strategies for Revascularization in Octogenarians - "Me and My Heart" Study - "MetCool ACS"- Metformin "Cooling" Effect on Metformin-naive Patients Treated With PCI Because of Acute Coronary Syndrome - "Preventing Cardiovascular Ischemic Events and Arresting Their Consequences in Type 2 Diabetic Population - "SVEAT" Chest Pain Scoring System - 1-month DAPT Plus 5-month Ticagrelor Monotherapy Versus 12-month DAPT in Patients With Drug-coated Balloon - 18F-NaF-PET for Identification of TCFA - 2D Strain Echocardiography for Diagnosing Chest Pain in the Emergency Room - 3rd Generation Resorbable Magnesium Scaffolds vs Biodegradable Polymer Stents in NSTE/ACS - 5th Generation cTnT in ED ACS - 99th Percentile Upper Reference Limit (URL) for the Meritas Troponin I Test - A Bioequivalence Study of SCH 530348 2.5 mg Tablets (P06558) - A Clinical Study of IMC-001 for Injection in Improving Atherosclerotic Plaque Stability in Patients With Acute Coronary Syndrome. - A Clinical Study of MT1002 in Subjects With Acute Coronary Syndrome Undergoing PCI - A Clinical Study on the Effect of Cardiopulmonary Function and Quality of Life in Patients With Acute Coronary Syndrome Complicated by Heart Failure by "Lying-Sitting-Standing" Sequential Baduanjin - A Clinical Trial Comparing Cangrelor to Clopidogrel Standard Therapy in Subjects Who Require Percutaneous Coronary Intervention (PCI) (CHAMPION PHOENIX) - A Clinical Trial of IntensiVE Dialysis - A Clinical Trial to Demonstrate the Efficacy of Cangrelor - A Clinical Trial to Evaluate the Effect of Food on PK and PD of Vicagrel Capsules in Healthy Adult Subjects - A Cohort of Patients Undergoing Percutaneous Coronary Intervention ### Approved drugs (11) - Bivalirudin - Cangrelor tetrasodium - Clopidogrel besilate - Clopidogrel bisulfate - Clopidogrel hydrobromide - Clopidogrel hydrochloride - Eptifibatide - Prasugrel besylate - Prasugrel hydrochloride - [Rivaroxaban](https://trialight.com/data/asset/rivaroxaban-3f354e10-6d35-4989-9e00-318be65808fb.md) - Ticagrelor ### Drugs in development (61) - Aliskiren Phase 2 - [Apixaban](https://trialight.com/data/asset/apixaban-9e91f03a-6eac-4da8-9f08-88d740399be5.md) Phase 3 - [Aspirin](https://trialight.com/data/asset/aspirin-03870fc6-137e-47aa-9f14-b7ae6754fb15.md) Phase 3 - Atopaxar Phase 2 - Atopaxar hydrobromide Phase 2 - Atorvastatin Phase 3 - Atreleuton Phase 2 - [Atuliflapon](https://trialight.com/data/asset/atuliflapon-850ef0c1-21fa-44ee-bad0-082cfb01dd83.md) Phase 2 - Bisoprolol fumarate Phase 2 - BMS-919373 Phase 1 - Cangrelor Phase 2 - Citalopram Phase 1 - Clopidogrel Phase 3 - [Colchicine](https://trialight.com/data/asset/colchicine-ae804b3e-3263-453f-abb3-ae1e813f2ccf.md) Phase 2 - [Dalcetrapib](https://trialight.com/data/asset/dalcetrapib-cc01e1b4-85ba-45ed-8edb-c960ab8aa4fb.md) Phase 3 - Darapladib Phase 3 - Darexaban Phase 2 - [Enoxaparin sodium](https://trialight.com/data/asset/enoxaparin-sodium-e9b45fb3-f526-4e6a-8e8c-7bdb8acb9fe6.md) Phase 1 - [Everolimus](https://trialight.com/data/asset/everolimus-0edf09a9-672d-4f9a-9e34-21ab083a92a4.md) Phase 1 - [Evolocumab](https://trialight.com/data/asset/evolocumab-ece543fe-0502-44c3-bef4-ec566503cced.md) Phase 3 ### Other linked drugs (5) - Adenosine diphosphate - Anistreplase - Dalteparin sodium - Isosorbide dinitrate - ST. 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