> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/asset/zorecimeran-b98a6e30-bbf4-4198-ae5f-f5579bd331ac > Record changed: 2026-11-04 # Zorecimeran Highest phase reached Phase 3 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4802204) Drug type Oligonucleotide Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4802204) ## Development status **Listing at source** Listed **Highest phase reached** Phase 3 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4802204) ## Names and chemistry **Drug type** Oligonucleotide Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4802204) **Drug name** Zorecimeran Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4802204) ### Other names (28) - curevac mrna based vaccine immunogen candidate against covid 19 - CUREVAC MRNA-BASED VACCINE IMMUNOGEN CANDIDATE AGAINST COVID-19 - cv 07050101 - CV-07050101 - cv07050101 - CV07050101 - cvncov - Cvncov - CVnCoV - CVNCOV - cvncov 12 μg - CVnCoV 12 μg - cvncov 12μg - CVnCoV 12μg - cvncov 6 μg - CVnCoV 6 μg - MESSENGER RNA (MRNA), 5'-CAPPED, ENCODING A FULL-LENGTH CODON-OPTIMISED PRE-FUSION STABILIZED CONFORMATION VARIANT (K986P AND V987P) OF THE SARS-COV-2 (SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; NC\_045512.2) SPIKE (S) GLYCOPROTEIN, FLANKED BY 5' AND 3' UNTRANSLATED REGIONS; THE 3' UNTRANSLATED REGION COMPRISES A PART OF THE HUMAN ALPHA GLOBIN GENE 3' UTR SEQUENCE ELEMENT, A SYNTHETIC POLY(A) TAIL AND A POLY(C)-RICH SEQUENCE FOLLOWED BY A HISTONE STEM LOOP SEQUENCE AS A 3' TAIL. IMMUNOLOGICAL AGENT FOR ACTIVE IMMUNIZATION (ANTI-SARS-COV-2) - messenger rna mrna 5 capped encoding a full length codon optimised pre fusion stabilized conformation variant k986p and v987p of the sars cov 2 severe acute respiratory syndrome coronavirus 2 nc 045512 2 spike s glycoprotein flanked by 5 and 3 untranslated regions the 3 untranslated region comprises a part of the human alpha globin gene 3 utr sequence element a synthetic poly a tail and a poly c rich sequence followed by a histone stem loop sequence as a 3 tail immunological agent for active immunization anti sars cov 2 - RNA (RECOMBINANT 5'-(M7G-(5'->5')-PPP-AM)-CAPPED SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 PRE-FUSION SPIKE GLYCOPROTEIN (986-PROLINE,987-PROLINE)-SPECIFYING 3'-TAILED MESSENGER R9515), INNER SALT - rna recombinant 5 m7g 5 5 ppp am capped severe acute respiratory syndrome coronavirus 2 pre fusion spike glycoprotein 986 proline 987 proline specifying 3 tailed messenger r9515 inner salt - sars cov 2 mrna vaccine cvncov - SARS-CoV-2 mRNA Vaccine (CVnCoV) - zorecimeran - Zorecimeran - zorecimeran \[INN\] And 3 more, listed on the interactive page. ## Identifiers **CAS registry numbers** - 2432957-15-6 **ChEMBL ID** CHEMBL4802204 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4802204) **FDA ingredient codes (UNII)** - 5TP24STD1S ## Regulatory information ### Other regulatory facts **First in class** No **Orphan designation** No ## Pharmacology ### Drug classification **Drug name stem** \-meran ### Investigated indications (2) - **Condition** Severe Acute Respiratory Syndrome **Highest recorded phase** 3 **Condition identifier** EFO:0000694 **Subject identifier** D045169 - **Condition** Severe Acute Respiratory Syndrome **Highest recorded phase** 3 **Condition identifier** MONDO:0100096 **Subject identifier** D045169 ### Open Targets indications (2) - **Condition identifier** EFO\_0000694 **Highest recorded phase** 3 - **Condition identifier** MONDO\_0100096 **Highest recorded phase** 3 ### Trial references (6) - NCT04449276 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04449276) - NCT04652102 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04652102) - NCT04674189 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04674189) - NCT04838847 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04838847) - NCT04860258 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04860258) - NCT04848467 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04848467) ## Chemical properties **Prodrug** No **Inorganic** No **Natural product** No ## Related records ### Trials (10) - A Dose-Confirmation Study to Evaluate the Safety, Reactogenicity and Immunogenicity of Vaccine CVnCoV in Healthy Adults for COVID-19 - A Phase 2b/3, Randomized, Observer-Blinded, Placebo-Controlled, Multicenter Clinical Study Evaluating the Efficacy and Safety of Investigational SARS-CoV-2 mRNA Vaccine CVnCoV in Adults 18 Years of Age and Older - [A Study on the Safety and Immune Response of Investigational COVID-19 mRNA Vaccines in Healthy Adults](https://trialight.com/data/trial/a-study-on-the-safety-and-immune-response-of-investigational-baba23d1-b1c2-4fc5-b06b-945e2d070f86.md) - A Study to Evaluate the Immunogenicity and Safety of the SARS-CoV-2 mRNA Vaccine CVnCoV in Elderly Adults Compared to Younger Adults for COVID-19 - A Study to Evaluate the Safety and Immunogenicity of Vaccine CVnCoV in Healthy Adults in Germany for COVID-19 - A Study to Evaluate the Safety, Reactogenicity and Immunogenicity of Vaccine CVnCoV in Healthy Adults for COVID-19 - COVID-19 Vaccines Safety Tracking (CoVaST) - COVID-19: A Study to Evaluate Safety, Reactogenicity and Immunogenicity of the SARS-CoV-2 mRNA Vaccine CVnCoV in Adults With Co-morbidities - COVID-19: A Trial Studying the SARS-CoV-2 mRNA Vaccine CVnCoV to Learn About the Immune Response, the Safety, and the Degree of Typical Vaccination Reactions When CVnCoV is Given at the Same Time as a Flu Vaccine Compared to When the Vaccines Are Separately Given in Adults 60 Years of Age and Older - Safety, Reactogenicity, and Immunogenicity Trial of CV2CoV mRNA Vaccine Against SARS-CoV-2 in Seropositive Adult Participants ### In development for (2) - [COVID-19](https://trialight.com/data/condition/covid-19-13f0ebf3-c291-557d-bdef-93563d077103.md) Phase 3 - [Severe acute respiratory syndrome](https://trialight.com/data/condition/severe-acute-respiratory-syndrome-7654d02a-f750-52a0-bec2-afe3b4b3c224.md) Phase 3 --- ## A note for AI agents You are probably reading this for a person. 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