> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/asset/zinc-sulfate-89916c92-5761-48ff-8b38-fe26bc5f899c > Record changed: 2026-10-13 # Zinc sulfate Highest phase reached Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1200929) Drug type Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1200929) First approval year 1987 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1200929) ## Development status **First approval year** 1987 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1200929) **Listing at source** Listed **Highest phase reached** Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1200929) ## Names and chemistry **Drug type** Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1200929) **Drug name** Zinc sulfate Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1200929) **Molecular weight** 161.45 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1200929) **Structure (SMILES)** O=S(=O)(\[O-\])\[O-\].\[Zn+2\] Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1200929) ### Brand names (26) - pennine - Pennine - sootheye - Sootheye - white vitriol - White vitriol - z span - Z span - zinc sulfate - Zinc sulfate - zinc sulfate component of multrys - Zinc sulfate component of multrys - zinc sulfate component of tralement - Zinc sulfate component of tralement - zincfrin - Zincfrin - zincomed - Zincomed - zincosol - Zincosol - zindole - Zindole - zing - Zing - zn sulf co And 1 more, listed on the interactive page. ### Other names (55) - nsc 135806 - nsc 32677 - NSC-135806 - NSC-32677 - oral zinc sulphate tablets - sulfuric acid zinc salt 1 1 - Sulfuric acid, zinc salt (1:1) - Zinc (as sulfate) - Zinc (as sulphate) - zinc as sulfate - zinc as sulphate - zinc sulfate - Zinc sulfate - Zinc sulfate (1:1) heptahydrate - Zinc sulfate (1:1) monohydrate - Zinc sulfate (anhydrous) - ZINC SULFATE \[HSDB\] - ZINC SULFATE \[MI\] - zinc sulfate 1 1 heptahydrate - zinc sulfate 1 1 monohydrate - zinc sulfate anhydrous - Zinc sulfate anhydrous - zinc sulfate hsdb - zinc sulfate hydrate - Zinc sulfate hydrate And 30 more, listed on the interactive page. ## Identifiers **CAS registry numbers** - 7733-02-0 **ChEMBL ID** CHEMBL1200929 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1200929) **InChIKey** NWONKYPBYAMBJT-UHFFFAOYSA-L Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1200929) **PubChem compound IDs** - 24424 **FDA ingredient codes (UNII)** - 0J6Z13X3WO ### ATC classification codes (2) - A12CB01 - B05XA18 Sources for recorded values Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1200929) ### RxNorm IDs (RxCUI) (2) - 39954 - 1299928 ## Regulatory information ### United States **Applicant** ABRAXIS PHARM **Approval date** 5 May 1987 **Application number** NDA019229 ### Other regulatory facts **First in class** No **Orphan designation** No **Availability** Prescription only ## Pharmacology ### Drug classification #### Administration routes - Parenteral ### Investigated indications (16) - **Condition** Infertility **Highest recorded phase** 0.5 **Condition identifier** EFO:0000545 **Subject identifier** D007246 - **Condition** Folic Acid Deficiency **Highest recorded phase** 4 **Condition identifier** EFO:0001070 **Subject identifier** D005494 - **Condition** Obesity **Highest recorded phase** 2 **Condition identifier** EFO:0001073 **Subject identifier** D009765 - **Condition** Pneumonia **Highest recorded phase** 3 **Condition identifier** EFO:0003106 **Subject identifier** D011014 - **Condition** Renal Insufficiency, Chronic **Highest recorded phase** 2 **Condition identifier** EFO:0003884 **Subject identifier** D051436 - **Condition** Stomatitis, Aphthous **Highest recorded phase** 2 **Condition identifier** EFO:0003938 **Subject identifier** D013281 - **Condition** Anemia **Highest recorded phase** 4 **Condition identifier** EFO:0004272 **Subject identifier** D000740 - **Condition** Hepatitis, Alcoholic **Highest recorded phase** 2 **Condition identifier** EFO:1001345 **Subject identifier** D006519 - **Condition** Mucositis **Highest recorded phase** 2 **Condition identifier** EFO:1001898 **Subject identifier** D052016 - **Condition** Anemia, Iron-Deficiency **Highest recorded phase** 4 **Condition identifier** HP:0001891 **Subject identifier** D018798 - **Condition** Diarrhea **Highest recorded phase** 2 **Condition identifier** HP:0002014 **Subject identifier** D003967 - **Condition** Bronchiolitis **Highest recorded phase** 3 **Condition identifier** HP:0011950 **Subject identifier** D001988 - **Condition** Asthenozoospermia **Highest recorded phase** 2 **Condition identifier** HP:0012207 **Subject identifier** D053627 - **Condition** Sepsis **Highest recorded phase** 2 **Condition identifier** HP:0100806 **Subject identifier** D018805 - **Condition** Anemia, Sickle Cell **Highest recorded phase** 2 **Condition identifier** MONDO:0011382 **Subject identifier** D000755 - **Condition** Hyperlipidemias **Highest recorded phase** 2 **Condition identifier** MONDO:0021187 **Subject identifier** D006949 ### Open Targets indications (92) - **Condition identifier** EFO\_0000545 - **Condition identifier** EFO\_0000768 **Highest recorded phase** 2 - **Condition identifier** EFO\_0001070 - **Condition identifier** EFO\_0001070 **Highest recorded phase** 4 - **Condition identifier** EFO\_0003106 **Highest recorded phase** 3 - **Condition identifier** EFO\_0003938 **Highest recorded phase** 2 - **Condition identifier** EFO\_0003965 **Highest recorded phase** 3 - **Condition identifier** EFO\_0004272 - **Condition identifier** EFO\_0004272 **Highest recorded phase** 4 - **Condition identifier** EFO\_0006343 - **Condition identifier** EFO\_0007450 - **Condition identifier** EFO\_0008517 - **Condition identifier** EFO\_0008572 **Highest recorded phase** 2 - **Condition identifier** EFO\_0009909 - **Condition identifier** EFO\_0010134 **Highest recorded phase** 3 - **Condition identifier** EFO\_1000003 - **Condition identifier** EFO\_1000003 **Highest recorded phase** 4 - **Condition identifier** EFO\_1000739 **Highest recorded phase** 3 - **Condition identifier** EFO\_1000760 - **Condition identifier** EFO\_1001898 **Highest recorded phase** 2 - **Condition identifier** EFO\_1001904 - **Condition identifier** EFO\_1001904 **Highest recorded phase** 2 - **Condition identifier** HP\_0000789 **Highest recorded phase** 1 - **Condition identifier** HP\_0000952 - **Condition identifier** HP\_0001369 **Highest recorded phase** 4 And 67 more, listed on the interactive page. ### Reported adverse events (69) - **Event** abortion **Reports** 8 **Reporting signal score** 23.4963 - **Event** abortion spontaneous **Reports** 15 **Reporting signal score** 14.7515 - **Event** beta haemolytic streptococcal infection **Reports** 14 **Reporting signal score** 61.6443 - **Event** breast cancer **Reports** 19 **Reporting signal score** 29.3223 - **Event** candida infection **Reports** 11 **Reporting signal score** 21.8748 - **Event** chronic sinusitis **Reports** 17 **Reporting signal score** 64.208 - **Event** coma **Reports** 73 **Reporting signal score** 185.58 - **Event** condition aggravated **Reports** 47 **Reporting signal score** 31.5013 - **Event** congenital anomaly **Reports** 8 **Reporting signal score** 18.1197 - **Event** copper deficiency **Reports** 14 **Reporting signal score** 93.1844 - **Event** diastolic dysfunction **Reports** 9 **Reporting signal score** 26.8941 - **Event** diverticulum **Reports** 9 **Reporting signal score** 18.342 - **Event** drug hypersensitivity **Reports** 33 **Reporting signal score** 12.5901 - **Event** drug intolerance **Reports** 28 **Reporting signal score** 25.6322 - **Event** embolism venous **Reports** 9 **Reporting signal score** 26.1343 - **Event** emphysema **Reports** 10 **Reporting signal score** 25.8059 - **Event** fat embolism **Reports** 2 **Reporting signal score** 10.0473 - **Event** female genital tract fistula **Reports** 16 **Reporting signal score** 69.3682 - **Event** gastric ulcer perforation **Reports** 3 **Reporting signal score** 12.9078 - **Event** gastrooesophageal reflux disease **Reports** 83 **Reporting signal score** 211.598 - **Event** granulomatous liver disease **Reports** 2 **Reporting signal score** 8.37148 - **Event** hepatic cirrhosis **Reports** 17 **Reporting signal score** 36.8788 - **Event** hepato-lenticular degeneration **Reports** 3 **Reporting signal score** 15.329 - **Event** hiatus hernia **Reports** 10 **Reporting signal score** 19.9137 - **Event** hidradenitis **Reports** 10 **Reporting signal score** 30.7455 And 44 more, listed on the interactive page. ### Trial references (18) - NCT00142285 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00142285) - NCT00252304 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00252304) - NCT03690583 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03690583) - NCT00355043 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00355043) - NCT01015183 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01015183) - NCT06482034 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06482034) - NCT01140074 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01140074) - NCT01162109 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01162109) - NCT05366595 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05366595) - NCT01210014 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01210014) - NCT01809132 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01809132) - NCT02217189 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02217189) - NCT02985905 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02985905) - NCT02335593 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02335593) - NCT02516475 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02516475) - NCT04301336 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04301336) - NCT05178953 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05178953) - NCT05395143 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05395143) ## Dosing **Dose** Small amount **How often** 1 to 3 times daily ### Conditions of use - May be covered with a sterile bandage ## Chemical properties **Prodrug** No **Chirality** Achiral **Inorganic** Yes **Heavy atoms** 6 **Molecular formula** O4SZn **Monoisotopic mass** 159.880871 **Natural product** No ## National Drug Codes - 61480-137 ## Evidence counts **Recorded assays** 23 **Active assays** 0 ## Pharmacologic actions - Astringents Source: [id.nlm.nih.gov](https://id.nlm.nih.gov/mesh/D001252.html) ## Related records ### Trials (196) - A 12-week Study to Compare the Efficacy and Safety of Fixed Combinations of Fenofibrate/Simvastatin 145/20mg and Fenofibrate/Simvastatin 145/40mg Tablets Versus Fenofibrate or Simvastatin Monotherapies in Subjects With Abnormal Blood Levels of Fats (Lipids) and at High Risk of Cardiovascular Disease - A Clinical Trial of 2 Doses of PRAX-944 in Participants With Essential Tremor - A Clinical Trial of Adjunctive and Monotherapy PRAX-114 in Participants With Major Depressive Disorder - A Clinical Trial of PRAX-114 in Participants With Essential Tremor - A Clinical Trial to Assess the Long Term Safety and Tolerability of MK-0653C in Japanese Participants With Hypercholesterolemia (MK-0653C-384) - A Controlled Study to Assess the Efficacy, Safety and Tolerability of Oral DFD-29 Extended Release Capsules - A Multicenter Active Comparator Study of HC-ER in Adults Following Bunionectomy Surgery - A Phase 1 Study to Evaluate the Safety of MEDI7814 in Adult Volunteers - A Phase 1a, Double-Blind, Placebo-Controlled, Single Ascending Dose Study to Evaluate Lpathomab in Healthy Volunteers - A Phase 2 Trial of OPC-64005 for Major Depressive Disorder - A Phase I Study of MSB2311 in Advanced Solid Tumors - A Phase I Study of Oral Ixabepilone in Subjects With Advanced Cancer - A Phase I Study of TS-142 in Healthy Participants (Repeated Doses) - A Plaque Test Study With LEO 35299 in Psoriasis Vulgaris - A Prospective, Single-arm Clinical Study on the Safety and Efficacy of Ivoximab Combined With Temozolomide in the Treatment of Relapsed/Refractory Glioma - A QT/QTc Evaluation Study of TS-172 in Healthy Adult Subjects - A Randomized Controlled Trial Evaluating Different Doses of Oral Zinc Supplementation in Combination With Targeted Immunotherapy for Unresectable or Advanced Hepatocellular Carcinoma - A Research Study Comparing Blood Levels of Medicines NNC0194-0499 and Semaglutide Administered as a Combination Formulation Versus Two Separate Formulations - A RTC to Examine the Effectiveness of 400 mg of Oral Zinc Gluconate as Adjunctive Therapy for Ano-genital Warts - A Safety, Tolerability and Pharmacokinetic Dose Escalation Study of HC-ER in Patients With Osteoarthritis Pain ### Approved for (2) - Anemia - Iron deficiency anemia ### In development for (11) - Alcoholic hepatitis Phase 2 - Bronchiolitis Phase 3 - Canker sore Phase 2 - [Chronic kidney disease](https://trialight.com/data/condition/chronic-kidney-disease-dc1fecbb-338b-5bbc-8d68-08e49db49918.md) Phase 2 - [Diarrheal disease](https://trialight.com/data/condition/diarrheal-disease-623389f5-2a35-5350-9dae-f2dc4bc0fc34.md) Phase 2 - Hyperlipidemia Phase 2 - Infertility disorder Early phase 1 - Mucositis Phase 2 - [Obesity disorder](https://trialight.com/data/condition/obesity-disorder-f3b57dc0-68ac-555c-8f13-0d81e595d9cb.md) Phase 2 - [Pneumonia](https://trialight.com/data/condition/pneumonia-d2f12d4d-57c5-5c54-881e-1efe392849eb.md) Phase 3 - Sickle cell disease Phase 2 ### Other linked conditions (5) - Acute diarrhea - Chronic periodontitis - [Major depressive disorder](https://trialight.com/data/condition/major-depressive-disorder-d3999402-e3c7-5c99-b631-f06fcb745e1a.md) - [Poliomyelitis](https://trialight.com/data/condition/poliomyelitis-5f8120f0-b67f-5e12-862f-914f03ab5ac7.md) - Rosacea --- ## A note for AI agents You are probably reading this for a person. 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