> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/asset/zinc-gluconate-59ac216f-8c9a-422d-b331-57b0ff0130f9
> Record changed: 2026-10-13

# Zinc gluconate

Highest phase reached

Phase 3

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL3833377)

Drug type

Small molecule

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL3833377)

## Development status

**Listing at source**

Listed

**Highest phase reached**

Phase 3

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL3833377)

## Names and chemistry

**Drug type**

Small molecule

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL3833377)

**Drug name**

Zinc gluconate

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL3833377)

**Molecular weight**

455.68

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL3833377)

**Structure (SMILES)**

O=C(\[O-\])\[C@H\](O)\[C@@H\](O)\[C@H\](O)\[C@H\](O)CO.O=C(\[O-\])\[C@H\](O)\[C@@H\](O)\[C@H\](O)\[C@H\](O)CO.\[Zn+2\]

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL3833377)

### Other names (32)

- bis d gluconato o1 o2 zinc
- Bis(d-gluconato-o1,o2) zinc
- gluconic acid zinc complex
- Gluconic acid zinc complex
- GLUCONIC ACID ZINC COMPLEX \[MI\]
- gluconic acid zinc complex mi
- zinc d gluconate 1 2
- Zinc d-gluconate (1:2)
- zinc gluconate
- Zinc gluconate
- ZINC GLUCONATE \[EP IMPURITY\]
- ZINC GLUCONATE \[EP MONOGRAPH\]
- ZINC GLUCONATE \[FCC\]
- ZINC GLUCONATE \[GREEN BOOK\]
- ZINC GLUCONATE \[HSDB\]
- ZINC GLUCONATE \[MART.\]
- ZINC GLUCONATE \[USP MONOGRAPH\]
- ZINC GLUCONATE \[VANDF\]
- Zinc gluconate \[WHO-DD\]
- zinc gluconate ep impurity
- zinc gluconate ep monograph
- zinc gluconate fcc
- zinc gluconate green book
- zinc gluconate hsdb
- zinc gluconate mart

And 7 more, listed on the interactive page.

## Identifiers

**ATC classification codes**

- A12CB02

Sources for recorded values

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL3833377)

**CAS registry numbers**

- 4468-02-4

**ChEMBL ID**

CHEMBL3833377

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL3833377)

**InChIKey**

WHMDKBIGKVEYHS-IYEMJOQQSA-L

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL3833377)

**RxNorm IDs (RxCUI)**

- 58300

**FDA ingredient codes (UNII)**

- U6WSN5SQ1Z

### PubChem compound IDs (2)

- 443445
- 452949

## Regulatory information

### Other regulatory facts

**First in class**

No

**Orphan designation**

No

## Pharmacology

### Investigated indications (4)

- **Condition**  
Jaundice, Neonatal

**Highest recorded phase**  
1

**Condition identifier**  
EFO:1000739

**Subject identifier**  
D007567
- **Condition**  
Dysphonia

**Highest recorded phase**  
1

**Condition identifier**  
MONDO:0000485

**Subject identifier**  
D055154
- **Condition**  
Diabetes Mellitus, Type 2

**Highest recorded phase**  
2

**Condition identifier**  
MONDO:0005148

**Subject identifier**  
D003924
- **Condition**  
Hepatolenticular Degeneration

**Highest recorded phase**

0.5

**Condition identifier**  
MONDO:0010200

**Subject identifier**  
D006527

### Open Targets indications (13)

- **Condition identifier**  
EFO\_0000280

**Highest recorded phase**  
1
- **Condition identifier**  
EFO\_1000003
- **Condition identifier**  
EFO\_1000739
- **Condition identifier**  
EFO\_1000739

**Highest recorded phase**  
1
- **Condition identifier**  
HP\_0000360
- **Condition identifier**  
HP\_0000952

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0000257

**Highest recorded phase**  
2
- **Condition identifier**  
MONDO\_0000485
- **Condition identifier**  
MONDO\_0000485

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0001209

**Highest recorded phase**  
2
- **Condition identifier**  
MONDO\_0010200
- **Condition identifier**  
MONDO\_0010200

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0013098

### Reported adverse events (78)

- **Event**  
acne fulminans

**Reports**  
2

**Reporting signal score**

9.96248
- **Event**  
ageusia

**Reports**  
21

**Reporting signal score**

67.0803
- **Event**  
anaemia macrocytic

**Reports**  
3

**Reporting signal score**

8.92787
- **Event**  
anosmia

**Reports**  
41

**Reporting signal score**

198.96
- **Event**  
asthma

**Reports**  
8

**Reporting signal score**

7.10929
- **Event**  
beta haemolytic streptococcal infection

**Reports**  
14

**Reporting signal score**

73.2643
- **Event**  
blood calcium decreased

**Reports**  
4

**Reporting signal score**

7.29276
- **Event**  
bone marrow eosinophilic leukocyte count increased

**Reports**  
1

**Reporting signal score**

6.73297
- **Event**  
burning sensation

**Reports**  
9

**Reporting signal score**

12.1782
- **Event**  
candida infection

**Reports**  
7

**Reporting signal score**

16.405
- **Event**  
chest discomfort

**Reports**  
10

**Reporting signal score**

9.04576
- **Event**  
chronic sinusitis

**Reports**  
7

**Reporting signal score**

25.966
- **Event**  
condition aggravated

**Reports**  
25

**Reporting signal score**

20.5887
- **Event**  
congenital anomaly

**Reports**  
6

**Reporting signal score**

16.7081
- **Event**  
copper deficiency

**Reports**  
14

**Reporting signal score**

104.836
- **Event**  
creatinine renal clearance decreased

**Reports**  
4

**Reporting signal score**

9.71459
- **Event**  
crystal nephropathy

**Reports**  
2

**Reporting signal score**

7.50129
- **Event**  
diastolic dysfunction

**Reports**  
7

**Reporting signal score**

24.8743
- **Event**  
disease recurrence

**Reports**  
7

**Reporting signal score**

11.3094
- **Event**  
diverticulum

**Reports**  
7

**Reporting signal score**

18.1264
- **Event**  
drug intolerance

**Reports**  
10

**Reporting signal score**

7.4379
- **Event**  
dysgeusia

**Reports**  
7

**Reporting signal score**

7.45918
- **Event**  
dyspnoea exertional

**Reports**  
8

**Reporting signal score**

12.0398
- **Event**  
eczema

**Reports**  
7

**Reporting signal score**

12.2221
- **Event**  
embolism venous

**Reports**  
7

**Reporting signal score**

24.2782

And 53 more, listed on the interactive page.

### Trial references (4)

- NCT00692224  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00692224)
- NCT01309620  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01309620)
- NCT03957720  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03957720)
- NCT05892770  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05892770)

## Chemical properties

**Prodrug**

No

**Chirality**

Single enantiomer

**Inorganic**

No

**Heavy atoms**

27

**Molecular formula**

C12H22O14Zn

**Monoisotopic mass**

454.030097

**Natural product**

Yes

## National Drug Codes

- 17312-077
- 52796-173
- 52796-174
- 52796-177

## Evidence counts

**Recorded assays**

1

**Active assays**

0

## Pharmacologic actions

- Trace Elements  
Source: [id.nlm.nih.gov](https://id.nlm.nih.gov/mesh/D014131.html)

## Related records

### Trials (11)

- Effect of Zinc on Barrett's Metaplasia
- Effect of Zinc on Glucose Homeostasis
- Efficacy of Zinc in Reducing Hyperbilirubinemia Among High Risk Neonates - A Double Blind Randomized Trial
- [Enhanced Dermatological Care to Reduce Rash and Paronychia in Epidermal Growth Factor Receptor (EGRF)-Mutated Non-Small Cell Lung Cancer (NSCLC) Treated First-line With Amivantamab Plus Lazertinib](https://trialight.com/data/trial/enhanced-dermatological-care-to-reduce-rash-and-paronychia-4fa4870a-680b-4f49-9357-9eaa67916bdf.md)
- Impact of Daily Zinc Supplementation to Infants Born With Low Birth Weight on Death and Severe Disease
- Improvement of Tinnitus After Oral Zinc on Patients With Noise-induced Hearing Loss
- The Effect of Platelet-rich Plasma Nasal Injection in the Treatment of Traumatic Olfactory Dysfunction
- The Individual Therapy for Patients With Wilson's Disease
- Zinc Effect on Inflammation and Cardiovascular Risk in HIV
- Zinc Intervention in Elderly for Prevention of Pneumonia
- Zinc Supplementation Prior to Botox Injections for Spasmodic Dysphonia

### In development for (4)

- Barrett esophagus Phase 1
- Spasmodic dystonia Phase 1
- [Type 2 diabetes mellitus](https://trialight.com/data/condition/type-2-diabetes-mellitus-98e14a90-bb06-5174-90c7-901a0a259fb9.md) Phase 2
- Wilson disease Early phase 1

---

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