> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/asset/xenon-823d22f5-381f-43f8-8ee3-f91ebdb28f1c > Record changed: 2026-10-13 # Xenon Highest phase reached Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1236802) Drug type Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1236802) First approval year 1982 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1236802) ## Development status **First approval year** 1982 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1236802) **Listing at source** Listed **Highest phase reached** Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1236802) ## Names and chemistry **Drug type** Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1236802) **Drug name** Xenon Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1236802) **Molecular weight** 131.29 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1236802) **Structure (SMILES)** These details could not be displayed. ### Other names (12) - xenon - Xenon - XENON \[JAN\] - XENON \[MART.\] - XENON \[MI\] - XENON \[VANDF\] - Xenon \[WHO-DD\] - xenon jan - xenon mart - xenon mi - xenon vandf - xenon who dd ## Identifiers **CAS registry numbers** - 7440-63-3 **ChEMBL ID** CHEMBL1236802 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1236802) **InChIKey** FHNFHKCVQCLJFQ-UHFFFAOYSA-N Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1236802) **RxNorm IDs (RxCUI)** - 11363 **FDA ingredient codes (UNII)** - 3H3U766W84 ### ATC classification codes (2) - N01AX15 - V04CX12 Sources for recorded values Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1236802) ### PubChem compound IDs (4) - 23991 - 175671520 - 175671525 - 175671534 ## Regulatory information ### United States **Applicant** CURIUM **Approval date** 9 Mar 1982 **Application number** NDA018327 ### Other regulatory facts **First in class** Yes **Orphan designation** No **Availability** Prescription only ## Pharmacology ### Drug classification #### Administration routes - Parenteral - topical ### Investigated indications (13) - **Condition** Pulmonary Disease, Chronic Obstructive **Highest recorded phase** 1 **Condition identifier** EFO:0000341 **Subject identifier** D029424 - **Condition** Obesity **Highest recorded phase** 1 **Condition identifier** EFO:0001073 **Subject identifier** D009765 - **Condition** Coronary Disease **Highest recorded phase** 3 **Condition identifier** EFO:0001645 **Subject identifier** D003327 - **Condition** Obsessive-Compulsive Disorder **Highest recorded phase** 2 **Condition identifier** EFO:0004242 **Subject identifier** D009771 - **Condition** Panic Disorder **Highest recorded phase** 2 **Condition identifier** EFO:0004262 **Subject identifier** D016584 - **Condition** Delirium **Highest recorded phase** 2 **Condition identifier** EFO:0009267 **Subject identifier** D003693 - **Condition** Hypothermia **Highest recorded phase** 2 **Condition identifier** HP:0002045 **Subject identifier** D007035 - **Condition** Ischemic Stroke **Highest recorded phase** 3 **Condition identifier** HP:0002140 **Subject identifier** D000083242 - **Condition** Depressive Disorder, Major **Highest recorded phase** 0.5 **Condition identifier** MONDO:0002009 **Subject identifier** D003865 - **Condition** Bipolar Disorder **Highest recorded phase** 0.5 **Condition identifier** MONDO:0004985 **Subject identifier** D001714 - **Condition** Brain Ischemia **Highest recorded phase** 2 **Condition identifier** MONDO:0005299 **Subject identifier** D002545 - **Condition** Cystic Fibrosis **Highest recorded phase** 0.5 **Condition identifier** MONDO:0009061 **Subject identifier** D003550 - **Condition** Brain Injuries **Highest recorded phase** 2 **Condition identifier** MONDO:0043510 **Subject identifier** D001930 ### Open Targets indications (29) - **Condition identifier** EFO\_0000341 - **Condition identifier** EFO\_0001073 **Highest recorded phase** 1 - **Condition identifier** EFO\_0001645 **Highest recorded phase** 3 - **Condition identifier** EFO\_0004242 **Highest recorded phase** 2 - **Condition identifier** EFO\_0004244 - **Condition identifier** EFO\_0004262 - **Condition identifier** EFO\_0004610 - **Condition identifier** EFO\_0009267 **Highest recorded phase** 2 - **Condition identifier** EFO\_0009492 **Highest recorded phase** 2 - **Condition identifier** EFO\_0009833 **Highest recorded phase** 3 - **Condition identifier** EFO\_0009954 **Highest recorded phase** 2 - **Condition identifier** HP\_0000739 **Highest recorded phase** 1 - **Condition identifier** HP\_0002045 **Highest recorded phase** 2 - **Condition identifier** HP\_0002140 **Highest recorded phase** 3 - **Condition identifier** HP\_0002647 - **Condition identifier** MONDO\_0002009 - **Condition identifier** MONDO\_0002009 **Highest recorded phase** 1 - **Condition identifier** MONDO\_0004985 - **Condition identifier** MONDO\_0004985 **Highest recorded phase** 1 - **Condition identifier** MONDO\_0005010 **Highest recorded phase** 3 - **Condition identifier** MONDO\_0005068 **Highest recorded phase** 3 - **Condition identifier** MONDO\_0005258 **Highest recorded phase** 1 - **Condition identifier** MONDO\_0005299 **Highest recorded phase** 2 - **Condition identifier** MONDO\_0005383 **Highest recorded phase** 2 - **Condition identifier** MONDO\_0006663 **Highest recorded phase** 2 And 4 more, listed on the interactive page. ### Trial references (18) - NCT00879892 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00879892) - NCT00934700 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00934700) - NCT01545271 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01545271) - NCT02071394 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02071394) - NCT01120405 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01120405) - NCT01285271 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01285271) - NCT01757106 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01757106) - NCT01948765 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01948765) - NCT01199276 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01199276) - NCT01262729 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01262729) - NCT02098148 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02098148) - NCT02220426 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02220426) - NCT03482960 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03482960) - NCT03748446 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03748446) - NCT03764163 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03764163) - NCT05433961 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05433961) - NCT04432155 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04432155) - NCT05335109 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05335109) ## Dosing **Dose** 75-100mL **Route** Inhalation **How often** As needed ### Conditions of use (2) - Administer dose within 5 minutes of DE measurement - Inhale the entire contents of one Dose Delivery Bag ## Chemical properties **Prodrug** No **Chirality** Achiral **Inorganic** Yes **Heavy atoms** 1 **Molecular formula** Xe **Monoisotopic mass** 131.90415508 **Natural product** No ## Pharmacologic actions - Anesthetics, Inhalation Source: [id.nlm.nih.gov](https://id.nlm.nih.gov/mesh/D018685.html) ## Related records ### Trials (54) - A Pre- and Post- Coronary Artery Bypass Graft Implantation Disposed Application of Xenon - A Test of Neural Inertia in Humans With Xenon - Anesthesia for Obese Patients: Desflurane Versus Xenon - Assessment of Chronic Lung Allograft Dysfunction Using Single-breath & Multi-breath Hyperpolarized Xenon-129 MRI - Cardiovascular Safety of Xenon in General Anaesthesia, in Patient With Cardiovascular Risk in Non Cardiac Surgery - Cerebral and Spinal Protection of Xenon Post-conditioning in Patients Undergoing Aortic Dissection Repair - Depth of Hypnosis and Postoperative Nausea and Vomiting During Xenon Anaesthesia - Dissolved Phase HXe-129 MRI: A Novel Biomarker to Quantify Pulmonary Pathology - Downstream Effects of Airway Mucus Plugs on 129Xenon MRI in Severe Asthma - Effect of Xenon and Therapeutic Hypothermia, on the Brain and on Neurological Outcome Following Brain Ischemia in Cardiac Arrest Patients - Effect of Xenon on Brain Injury After Aneurysmal Subarachnoid Hemorrhage - Evaluating the Effect of Benralizumab in Severe, Poorly-controlled Eosinophilic Asthma Using Inhaled Hyperpolarized 129-Xenon MRI - Evaluation of Brain Damage Resulting From Carotid Endarterectomy With Xenon Anesthesia - Evaluation of Ventilation Defects Downstream of Mucus Plugs in Patients With Muco-Obstructive Lung Disease - Functional and Structural Assessment of Endobronchial Valve Recipients Using Dynamic Hyperpolarized Xenon-129 MRI - Functional Lung Avoidance Radiation Therapy Using Hyperpolarized Xenon-129 MRI - Gas Exchange MRI to Visualize Regional Therapy Response in Interstitial Lung Disease - General Anesthesia With Xenon in Inspiratory Concentrations of 50% and 70% and Total I.V. Anaesthesia. - Hemodynamic Stability During Carotid Endarterectomy.Comparison of LENOXe™ (Xenon 100% v/v) Versus Sevoflurane - Hip Fracture Surgery in Elderly Patients ### In development for (12) - Bipolar disorder Early phase 1 - Brain injury Phase 2 - Brain ischemia Phase 2 - [Chronic obstructive pulmonary disease](https://trialight.com/data/condition/chronic-obstructive-pulmonary-disease-8e23f74b-95b9-5920-a241-c0278555234f.md) Phase 1 - [Coronary artery disorder](https://trialight.com/data/condition/coronary-artery-disorder-6f736849-d477-587a-b3fa-b0621d573407.md) Phase 3 - [Cystic fibrosis](https://trialight.com/data/condition/cystic-fibrosis-6f9870eb-6ebc-5bec-a50b-34b0b323a7c3.md) Early phase 1 - Delirium Phase 2 - [Ischemic stroke](https://trialight.com/data/condition/ischemic-stroke-22957443-39c1-55ea-8c6d-d5be07d42dc0.md) Phase 3 - [Major depressive disorder](https://trialight.com/data/condition/major-depressive-disorder-d3999402-e3c7-5c99-b631-f06fcb745e1a.md) Early phase 1 - [Obesity disorder](https://trialight.com/data/condition/obesity-disorder-f3b57dc0-68ac-555c-8f13-0d81e595d9cb.md) Phase 1 - Obsessive-compulsive disorder Phase 2 - Panic disorder Phase 2 ### Other linked conditions (2) - [Acute lung injury](https://trialight.com/data/condition/acute-lung-injury-fb11c447-d7f6-5c24-8fb9-764bbaaabced.md) - [Interstitial lung disease](https://trialight.com/data/condition/interstitial-lung-disease-745f5770-ba0b-517d-b691-5b9731a03266.md) --- ## A note for AI agents You are probably reading this for a person. 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