> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/asset/xelafaslatide-acaa45ff-a64e-4124-8a4b-a43b2a5ddf5a > Record changed: 2026-10-13 # Xelafaslatide Highest phase reached Phase 2 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068318) Drug type Protein Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068318) ## Development status **Listing at source** Listed **Highest phase reached** Phase 2 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068318) ## Names and chemistry **Drug type** Protein Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068318) **Drug name** Xelafaslatide Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068318) ### Other names (23) - his his ile tyr leu gly ala val asn tyr ile tyr nh2 - HIS-HIS-ILE-TYR-LEU-GLY-ALA-VAL-ASN-TYR-ILE-TYR-NH2 - l histidyl l histidyl l isoleucyl l tyrosyl l leucylglycyl l alanyl l valyl l asparaginyl ltyrosyl l isoleucyl l tyrosinamide - L-Histidyl-L-histidyl-L-isoleucyl-L-tyrosyl-L-leucylglycyl-L-alanyl-L-valyl-L-asparaginyl-Ltyrosyl-L-isoleucyl-L-tyrosinamide - onl 1204 - Onl-1204 - onl1204 - Onl1204 - ONL1204 - onl1204 c terminal nh2 - ONL1204 C-terminal NH2 - ONL1204 Ophthalmic solution - ONL1204 Ophthalmic Solution - ONL1204 Ophthalmic solution (Dose A) - ONL1204 Ophthalmic solution (Dose B) - xelafaslatida - Xelafaslatida - xelafaslatide - Xelafaslatide - xelafaslatide \[INN\] - XELAFASLATIDE \[USAN\] - xelafaslatide inn - xelafaslatide usan ## Identifiers **CAS registry numbers** - 2040964-58-5 **ChEMBL ID** CHEMBL6068318 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068318) **PubChem compound IDs** - 122677428 **FDA ingredient codes (UNII)** - XNA75YDV3F ## Regulatory information ### Other regulatory facts **First in class** No **Orphan designation** No ## Pharmacology ### Drug classification **Drug name stem** \-tide ### Investigated indications (2) - **Condition** Glaucoma, Open-Angle **Highest recorded phase** 1 **Condition identifier** EFO:0004190 **Subject identifier** D005902 - **Condition** Geographic Atrophy **Highest recorded phase** 1 **Condition identifier** EFO:1001492 **Subject identifier** D057092 ### Open Targets indications (6) - **Condition identifier** EFO\_0004190 **Highest recorded phase** 1 - **Condition identifier** EFO\_1001492 **Highest recorded phase** 1 - **Condition identifier** EFO\_1001492 **Highest recorded phase** 2 - **Condition identifier** MONDO\_0005150 **Highest recorded phase** 2 - **Condition identifier** MONDO\_0005338 **Highest recorded phase** 1 - **Condition identifier** MONDO\_0005464 **Highest recorded phase** 2 ### Trial references (2) - NCT04744662 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04744662) - NCT05160805 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05160805) ## Chemical properties **Prodrug** No **Chirality** Single enantiomer **Inorganic** No **Natural product** No ### Sequences - **Component** Sequence **Type** Protein **Sequence** HHIYLGAVNY ## Related records ### Trials (50) - A 3-way Cross-over Study on the Effects of QRL-101 on Transcranial Magnetic Stimulation and Nerve Excitability in Healthy Participants - A 4-Arm Efficacy and Safety Study of RT001 for the Treatment of Moderate to Severe Lateral Canthal Lines in Adults - A First in Human Study to Assess the Safety, Tolerability, and Pharmacokinetics of EDK060 in Adults With CMT1A. - A First-in-human Study of S230815 in Pediatric Participants With KCNT1-related Developmental and Epileptic Encephalopathy - A Phase 1/2 Multicenter, Randomized, Study to Evaluate the Safety and Efficacy of VS101 Subconjunctival Latanoprost Insert in Subjects With Open-Angle Glaucoma or Ocular Hypertension - A Phase 1b Study of ONL1204 Ophthalmic Solution in Patients with Progressing Open Angle Glaucoma - A Phase 2 Study to Assess the Safety and Efficacy of Intravitreal ONL1204 Ophthalmic Solution in Subjects With Mac-off Retinal Detachment - A Safety and Efficacy Study of a Range of Linaclotide Doses Administered Orally to Children Ages 6-17 Years Who Fulfill Modified Rome III Criteria for Child/Adolescent Functional Constipation (FC) - A Safety, Tolerability and Pharmacokinetics Study of Topical Ointment YR001 in Adult Healthy Volunteers - A Study of LNK01001 Capsule in Moderately to Severely Active Rheumatoid Arthritis - A Study of LNK01001 Capsule in Patients With Moderate to Severe Atopic Dermatitis - A Study of TX000045 in Patients With Pulmonary Hypertension Secondary to Heart Failure With Preserved Ejection Fraction (the APEX Study) - A Study on the Immune Response and Safety of a Multicomponent Shigella Vaccine in Preventing Shigellosis in Infants - A Study on the Safety, Reactogenicity, and Immune Response to the GVGH iNTS-GMMA Vaccine Against Invasive Nontyphoidal Salmonella in Adults, Children, and Infants - A Study to Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study) - A Study To Assess The Safety Of PF-06342674 In Adults With Type 1 Diabetes - A Study To Assess The Safety Of PF-06342674 In Healthy Volunteers - A Study to Evaluate 608 in Patients with Ankylosing Spondylitis (AS) - A Study to Evaluate Comparative Bioavailability of BMS-986278 in Healthy Participants - [A Study to Evaluate IPN10200 Safety and Efficacy in the Prevention of Episodic or Chronic Migraine in Adults](https://trialight.com/data/trial/a-study-to-evaluate-ipn10200-safety-and-efficacy-in-the-9c6a4942-79d6-4510-9919-691cc65fea01.md) ### In development for (1) - [Open-angle glaucoma](https://trialight.com/data/condition/open-angle-glaucoma-fb887921-4122-599b-b8a0-928b40ddc7a2.md) Phase 1 --- ## A note for AI agents You are probably reading this for a person. 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