> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/asset/vorinostat-ae074418-90c3-4664-ba21-68c35e010c8f > Record changed: 2026-10-13 # Vorinostat Highest phase reached Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL98) Drug type Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL98) First approval year 2006 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL98) ## Development status **First approval year** 2006 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL98) **Listing at source** Listed **Highest phase reached** Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL98) ## Names and chemistry **Drug type** Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL98) **Drug name** Vorinostat Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL98) **Molecular weight** 264.32 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL98) **Structure (SMILES)** O=C(CCCCCCC(=O)Nc1ccccc1)NO Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL98) ### Brand names (2) - zolinza - Zolinza ### Other names (39) - azacitidine and oral vorinostat - mk 0683 - MK-0683 - mk0683 - MK0683 - N-hydroxy-N'-phenyl-octanediamide (Vorinostat) - nsc 701852 - nsc 748799 - nsc 759852 - NSC-701852 - NSC-748799 - NSC-759852 - suberoylanilide hydroxamic acid - Suberoylanilide hydroxamic acid - vorinostat - Vorinostat - VORINOSTAT - vorinostat (MK0683 ) - Vorinostat (SAHA) - vorinostat (suberoylanilide hydroxamic acid) - Vorinostat (VOR) - vorinostat \[INN\] - VORINOSTAT \[JAN\] - VORINOSTAT \[MART.\] - VORINOSTAT \[MI\] And 14 more, listed on the interactive page. ## Identifiers **ATC classification codes** - L01XH01 Sources for recorded values Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL98) **CAS registry numbers** - 149647-78-9 **ChEMBL ID** CHEMBL98 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL98) **InChIKey** WAEXFXRVDQXREF-UHFFFAOYSA-N Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL98) **PubChem compound IDs** - 5311 **RxNorm IDs (RxCUI)** - 194337 **FDA ingredient codes (UNII)** - 58IFB293JI ## Regulatory information ### United States **Applicant** MSD SUB MERCK **Approval date** 6 Oct 2006 **Application number** NDA021991 ### European Union **Status** application\_withdrawn **Status date** 13 Feb 2009 **Product number** EMEA/H/C/000947 **Authorisation holder** Merck Sharp Dohme Limited **Priority medicines scheme** No **Generic** No **Biosimilar** No **Generic medicines** 0 **Biosimilar medicines** 0 **Advanced therapy** No **Conditional approval** No **Additional monitoring** No **Accelerated assessment** No **Exceptional circumstances** No #### Therapeutic areas - Lymphoma, T-Cell, Cutaneous European medicines record Source: [www.ema.europa.eu](https://www.ema.europa.eu/en/medicines/human/EPAR/vorinostat-msd) ### Other regulatory facts **Patents** 3 **Designations** 3 **Earliest recorded loss of exclusivity** 18 Mar 2028 **First in class** No **Fast track** Yes **Breakthrough designation** No **Orphan designation** No **Priority review** Yes **Orphan exclusivity** No **Accelerated approval** No **Availability** Prescription only ## Pharmacology ### Drug classification **Pharmacology name** vorinostat **Type** Synthetic organic **Drug name stem** \-stat **Approval recorded by Guide to Pharmacology** Yes #### Administration routes - Oral ### Mechanisms of action (13) - **Action** Inhibition **Action type** Inhibitor **Target** histone deacetylase 3 **Gene symbol** HDAC3 **Protein identifier** O15379 **Median affinity** 8.3 **Affinity units** pKi - **Action** Inhibition **Action type** Inhibitor **Target** histone deacetylase 1 **Gene symbol** HDAC1 **Protein identifier** Q13547 **Median affinity** 8.89 **Affinity units** pKi **Primary target** Yes - **Action** Inhibition **Action type** Inhibitor **Target** histone deacetylase 2 **Gene symbol** HDAC2 **Protein identifier** Q92769 **Median affinity** 8.8 **Affinity units** pKi - **Action** Inhibition **Action type** Inhibitor **Target** histone deacetylase 10 **Gene symbol** HDAC10 **Protein identifier** Q969S8 **Median affinity** 7.3 **Affinity units** pKi - **Action** Inhibition **Action type** Inhibitor **Target** histone deacetylase 11 **Gene symbol** HDAC11 **Protein identifier** Q96DB2 **Median affinity** 7.44 **Affinity units** pKi - **Action** Inhibition **Action type** Inhibitor **Target** histone deacetylase 8 **Gene symbol** HDAC8 **Protein identifier** Q9BY41 **Affinity units** pKi - **Action** Inhibition **Action type** Inhibitor **Target** histone deacetylase 6 **Gene symbol** HDAC6 **Protein identifier** Q9UBN7 **Median affinity** 8.8 **Affinity units** pKi - **Action** Inhibition **Action type** Inhibitor **Target** histone deacetylase 9 **Gene symbol** HDAC9 **Protein identifier** Q9UKV0 **Median affinity** 7.19 **Affinity units** pKi - **Action** Inhibition **Action type** Inhibitor **Target** histone deacetylase 5 **Gene symbol** HDAC5 **Protein identifier** Q9UQL6 **Median affinity** 5.44 **Affinity units** pKi - **Mechanism** Histone deacetylase 1 inhibitor **Action type** Inhibitor **Target** Histone deacetylase 1 **Protein identifier** Q13547 - **Mechanism** Histone deacetylase 2 inhibitor **Action type** Inhibitor **Target** Histone deacetylase 2 **Protein identifier** Q92769 - **Mechanism** Histone deacetylase 3 inhibitor **Action type** Inhibitor **Target** Histone deacetylase 3 **Protein identifier** O15379 - **Mechanism** Histone deacetylase 6 inhibitor **Action type** Inhibitor **Target** Protein deacetylase HDAC6 **Protein identifier** Q9UBN7 ### Open Targets mechanisms (4) - **Mechanism** Histone deacetylase 1 inhibitor **Action type** Inhibitor **Target** Histone deacetylase 1 - **Mechanism** Histone deacetylase 2 inhibitor **Action type** Inhibitor **Target** Histone deacetylase 2 - **Mechanism** Histone deacetylase 3 inhibitor **Action type** Inhibitor **Target** Histone deacetylase 3 - **Mechanism** Histone deacetylase 6 inhibitor **Action type** Inhibitor **Target** Protein deacetylase HDAC6 ### DrugCentral mechanisms (4) - **Action type** Inhibitor **Gene symbol** HDAC3 **Protein identifier** O15379 **Organism** Homo sapiens **Target development level** Clinical - **Action type** Inhibitor **Gene symbol** HDAC1 **Protein identifier** Q13547 **Organism** Homo sapiens **Target development level** Clinical - **Action type** Inhibitor **Gene symbol** HDAC2 **Protein identifier** Q92769 **Organism** Homo sapiens **Target development level** Clinical - **Action type** Inhibitor **Gene symbol** HDAC6 **Protein identifier** Q9UBN7 **Organism** Homo sapiens **Target development level** Clinical ### Investigated indications (96) - **Condition** Leukemia, Lymphocytic, Chronic, B-Cell **Highest recorded phase** 2 **Condition identifier** EFO:0000095 **Subject identifier** D015451 - **Condition** Lymphoma, Follicular **Highest recorded phase** 2 **Condition identifier** EFO:0000096 **Subject identifier** D008224 - **Condition** HIV Infections **Highest recorded phase** 2 **Condition identifier** EFO:0000180 **Subject identifier** D015658 - **Condition** Carcinoma, Squamous Cell **Highest recorded phase** 1 **Condition identifier** EFO:0000181 **Subject identifier** D002294 - **Condition** Hodgkin Disease **Highest recorded phase** 2 **Condition identifier** EFO:0000183 **Subject identifier** D006689 - **Condition** Lymphoma, B-Cell, Marginal Zone **Highest recorded phase** 2 **Condition identifier** EFO:0000191 **Subject identifier** D018442 - **Condition** Myelodysplastic Syndromes **Highest recorded phase** 2 **Condition identifier** EFO:0000198 **Subject identifier** D009190 - **Condition** Neoplasms, Plasma Cell **Highest recorded phase** 1 **Condition identifier** EFO:0000200 **Subject identifier** D054219 - **Condition** Lymphoma, T-Cell, Peripheral **Highest recorded phase** 1 **Condition identifier** EFO:0000211 **Subject identifier** D016411 - **Condition** Precursor Cell Lymphoblastic Leukemia-Lymphoma **Highest recorded phase** 2 **Condition identifier** EFO:0000220 **Subject identifier** D054198 - **Condition** Leukemia, Myeloid, Acute **Highest recorded phase** 3 **Condition identifier** EFO:0000222 **Subject identifier** D015470 - **Condition** Leukemia, Promyelocytic, Acute **Highest recorded phase** 1 **Condition identifier** EFO:0000224 **Subject identifier** D015473 - **Condition** Burkitt Lymphoma **Highest recorded phase** 1 **Condition identifier** EFO:0000309 **Subject identifier** D002051 - **Condition** Leukemia, Myelogenous, Chronic, BCR-ABL Positive **Highest recorded phase** 1 **Condition identifier** EFO:0000339 **Subject identifier** D015464 - **Condition** Carcinoma, Renal Cell **Highest recorded phase** 2 **Condition identifier** EFO:0000349 **Subject identifier** D002292 - **Condition** Colorectal Neoplasms **Highest recorded phase** 2 **Condition identifier** EFO:0000365 **Subject identifier** D015179 - **Condition** Crohn Disease **Highest recorded phase** 1 **Condition identifier** EFO:0000384 **Subject identifier** D003424 - **Condition** Lymphoma, Large B-Cell, Diffuse **Highest recorded phase** 1 **Condition identifier** EFO:0000403 **Subject identifier** D016403 - **Condition** Thrombocythemia, Essential **Highest recorded phase** 2 **Condition identifier** EFO:0000479 **Subject identifier** D013920 - **Condition** Adenocarcinoma, Follicular **Highest recorded phase** 2 **Condition identifier** EFO:0000501 **Subject identifier** D018263 - **Condition** Glioblastoma **Highest recorded phase** 2 **Condition identifier** EFO:0000519 **Subject identifier** D005909 - **Condition** Leukemia **Highest recorded phase** 2 **Condition identifier** EFO:0000565 **Subject identifier** D007938 - **Condition** Lymphoma **Highest recorded phase** 3 **Condition identifier** EFO:0000574 **Subject identifier** D008223 - **Condition** Mesothelioma **Highest recorded phase** 3 **Condition identifier** EFO:0000588 **Subject identifier** D008654 - **Condition** Neoplasms **Highest recorded phase** 4 **Condition identifier** EFO:0000616 **Subject identifier** D009369 And 71 more, listed on the interactive page. ### Open Targets indications (165) - **Condition identifier** EFO\_0000096 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000180 - **Condition identifier** EFO\_0000183 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000198 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000211 - **Condition identifier** EFO\_0000222 **Highest recorded phase** 3 - **Condition identifier** EFO\_0000384 - **Condition identifier** EFO\_0000479 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000501 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000519 **Highest recorded phase** 1 - **Condition identifier** EFO\_0000565 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000574 **Highest recorded phase** 3 - **Condition identifier** EFO\_0000588 **Highest recorded phase** 3 - **Condition identifier** EFO\_0000616 - **Condition identifier** EFO\_0000621 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000641 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000681 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000702 - **Condition identifier** EFO\_0000756 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000764 **Highest recorded phase** 2 - **Condition identifier** EFO\_0001378 **Highest recorded phase** 3 - **Condition identifier** EFO\_0002429 **Highest recorded phase** 2 - **Condition identifier** EFO\_0002618 - **Condition identifier** EFO\_0002913 - **Condition identifier** EFO\_0003060 And 140 more, listed on the interactive page. ### Reported adverse events (37) - **Event** activated partial thromboplastin time prolonged **Reports** 17 **Reporting signal score** 45.3588 - **Event** acute febrile neutrophilic dermatosis **Reports** 6 **Reporting signal score** 15.112 - **Event** anaemia **Reports** 74 **Reporting signal score** 68.4043 - **Event** anorexia **Reports** 9 **Reporting signal score** 13.2887 - **Event** blood creatinine increased **Reports** 19 **Reporting signal score** 13.3526 - **Event** decreased appetite **Reports** 45 **Reporting signal score** 36.1278 - **Event** dehydration **Reports** 67 **Reporting signal score** 88.4422 - **Event** diarrhoea **Reports** 74 **Reporting signal score** 21.9022 - **Event** electrocardiogram qt prolonged **Reports** 36 **Reporting signal score** 57.6679 - **Event** electrolyte imbalance **Reports** 9 **Reporting signal score** 14.0681 - **Event** embolism **Reports** 12 **Reporting signal score** 25.9419 - **Event** febrile neutropenia **Reports** 104 **Reporting signal score** 230.271 - **Event** haematotoxicity **Reports** 12 **Reporting signal score** 22.8181 - **Event** hyperglycaemia **Reports** 24 **Reporting signal score** 35.5265 - **Event** hyperuricaemia **Reports** 6 **Reporting signal score** 12.1799 - **Event** hypocalcaemia **Reports** 13 **Reporting signal score** 16.1405 - **Event** hypokalaemia **Reports** 33 **Reporting signal score** 45.915 - **Event** hyponatraemia **Reports** 20 **Reporting signal score** 13.6187 - **Event** hypophosphataemia **Reports** 17 **Reporting signal score** 41.8787 - **Event** hypoxia **Reports** 14 **Reporting signal score** 14.0953 - **Event** infection **Reports** 25 **Reporting signal score** 14.4101 - **Event** lymphocyte count decreased **Reports** 11 **Reporting signal score** 12.8054 - **Event** lymphopenia **Reports** 36 **Reporting signal score** 87.1088 - **Event** mucosal inflammation **Reports** 15 **Reporting signal score** 16.8418 - **Event** mycosis fungoides **Reports** 9 **Reporting signal score** 32.1662 And 12 more, listed on the interactive page. ### Trial references (201) - NCT00005634 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00005634) - NCT00109109 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00109109) - NCT00111813 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00111813) - NCT00310024 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00310024) - NCT00642954 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00642954) - NCT00729118 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00729118) - NCT00744354 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00744354) - NCT00773747 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00773747) - NCT00773838 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00773838) - NCT00839956 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00839956) - NCT00857324 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00857324) - NCT00858234 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00858234) - NCT01038388 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01038388) - NCT01297764 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01297764) - NCT01394354 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01394354) - NCT01492881 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01492881) - NCT01501370 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01501370) - NCT01502085 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01502085) - NCT01554852 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01554852) - NCT01720875 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01720875) - NCT02114502 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02114502) - NCT00330161 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00330161) - NCT01174199 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01174199) - NCT06145633 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06145633) - NCT00816283 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00816283) And 176 more, listed on the interactive page. ## Dosing **Dose** 400mg **Route** Oral **How often** Once daily ### Conditions of use - Take with food ## Chemical properties **Hydrogen bond acceptors** 3 **Hydrogen bond donors** 3 **Polar surface area** 78.43 **Calculated partition coefficient (ALogP)** 2.47 **Calculated partition coefficient (XLogP)** 1.9 **Prodrug** No **Chirality** Achiral **Inorganic** No **Rule-of-five violations** 0 **Rotatable bonds** 8 **Heavy atoms** 19 **Molecular formula** C14H20N2O3 **Monoisotopic mass** 264.14739250 **Natural product** Yes ## National Drug Codes - 0006-0568 ## Evidence counts **Recorded assays** 15,429 **Active assays** 7,109 ### Active assay types (4) - Confirmatory - Other - Screening - Summary ## Pharmacologic actions - Antineoplastic Agents Source: [id.nlm.nih.gov](https://id.nlm.nih.gov/mesh/D000970.html) - Histone Deacetylase Inhibitors Source: [id.nlm.nih.gov](https://id.nlm.nih.gov/mesh/D056572.html) ## Biological measurements These details could not be displayed. ## Related records ### Trials (342) - 131I-MIBG Alone VS. 131I-MIBG With Vincristine and Irinotecan VS131I-MIBG With Vorinostat - A Clinical Study Evaluating the Efficacy and Safety of CMS-D001 Tablets in the Treatment of Adult Patients With Moderate to Severe Plaque-type Psoriasis - A Clinical Trial of Oral Suberoylanilide Hydroxamic Acid (SAHA) in Patients With Advanced Multiple Myeloma (0683-004) - A Clinical Trial of Oral Suberoylanilide Hydroxamic Acid (SAHA) in Patients With Relapsed or Refractory Breast, Colorectal and Non-Small Cell Lung Cancer (0683-011)(TERMINATED) - A Clinical Trial of Vorinostat (MK0683, SAHA) in Combination With FDA Approved Cancer Drugs in Patients With Advanced Non-Small Cell Lung Cancer (NSCLC)(0683-056) - A Clinical Trial to Validate Molecular Targets of Vorinostat in Patients With Aerodigestive Tract Cancer - A Continuation Clinical Trial of Oral Vorinostat (MK-0683) in Advanced Cancers (MK-0683-007) - A Crossover Study to Assess the Effects of Vorinostat (MK0683, SAHA) in Patients With Advanced Cancer (0683-070)(COMPLETED) - A Dose Ranging Placebo-controlled Double-blind Study to Evaluate the Safety, Pharmacokinetics and Efficacy of 610 in Participants With Severe Eosinophilic Asthma - A First Time in Human Study to Assess GSK2336805 in Healthy Volunteers and Single Doses in Chronically Infected Hepatitis C Patients. - A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase Ⅱ Clinical Study to Evaluate the Efficacy and Safety of CMS-D001 in Adult Patients With Moderate to Severe Atopic Dermatitis - A Phase 2b Clinical Study of JDB0131 Benzenesulfonate Tablets - A Phase I Clinical Study on SHR6390 in Healthy Chinese Volunteers - A Phase I Study of Vorinostat and Bortezomib in Children With Refractory of Recurrent Solid Tumors, Including CNS Tumors and Lymphomas - A Phase I Trial of Vorinostat in Combination With Bevacizumab & Irinotecan in Recurrent Glioblastoma - A Phase I/II Clinical Trial of Vorinostat in Combination With Erlotinib for Patients With Relapsed/Refractory Non-Small-Cell Lung Cancer (0683-025) - A Phase I/II Study of First Line Vorinostat With Pemetrexed-cisplatin, in Patients With Malignant Pleural Mesothelioma - A Phase I/II Study of Paclitaxel Plus Carboplatin Plus Vorinostat in Recurrent Ovarian Cancer - A Phase II Clinical Trial of Flonoltinib Maleate Tablet in Intermediate-High Risk Myelofibrosis - A Phase II Study of 610 in Participants With Severe Eosinophilic Asthma ### Approved for (4) - [Cancer](https://trialight.com/data/condition/cancer-703b1dfc-4812-50eb-83f4-d7a205d16bdb.md) - Neoplasm - [Primary cutaneous T-cell non-Hodgkin lymphoma](https://trialight.com/data/condition/primary-cutaneous-t-cell-non-hodgkin-lymphoma-256d9a2d-c476-5c4c-9735-e4de59228289.md) - T-cell non-Hodgkin lymphoma ### In development for (94) - [Acquired polycythemia vera](https://trialight.com/data/condition/acquired-polycythemia-vera-5c3132a8-49a0-5b93-b3d6-cd5f1fa9e10e.md) Phase 2 - ACTH-dependent Cushing syndrome Phase 2 - Acute leukemia of ambiguous lineage Phase 2 - Acute lymphoblastic leukemia Phase 2 - [Acute myeloid leukemia](https://trialight.com/data/condition/acute-myeloid-leukemia-b0971a7a-c18d-544e-bd7f-b1a13b9caa30.md) Phase 3 - Acute promyelocytic leukemia Phase 1 - Adult glioblastoma Phase 2 - [Alzheimer disease](https://trialight.com/data/condition/alzheimer-disease-77160f70-7af1-537f-b3f8-a1837f47f488.md) Phase 1 - Anaplastic astrocytoma Phase 2 - Anaplastic oligodendroglioma Phase 1 - Anus cancer Phase 1 - [B-cell chronic lymphocytic leukemia](https://trialight.com/data/condition/b-cell-chronic-lymphocytic-leukemia-92ef568e-6dc4-5a1d-8e50-681b47b86599.md) Phase 2 - Brain cancer Phase 2 - [Brain disorder](https://trialight.com/data/condition/brain-disorder-4e393319-afcc-52a0-8ac4-4c73ea743874.md) Phase 2 - [Brain neoplasm](https://trialight.com/data/condition/brain-neoplasm-b3dac71b-1d7b-5a65-8f64-89821506ad41.md) Phase 2 - [Breast cancer](https://trialight.com/data/condition/breast-cancer-8ac10da3-93bd-54c5-a93b-265bc6699689.md) Phase 2 - [Breast neoplasm](https://trialight.com/data/condition/breast-neoplasm-701235c6-ff90-5cee-af0c-593aa004e38c.md) Phase 2 - Burkitt lymphoma Phase 1 - Childhood acute lymphoblastic leukemia Phase 2 - Chronic myeloid leukemia Phase 1 ### Targets (4) - [HDAC1](https://trialight.com/data/target/hdac1-8fadff30-6e38-5bb8-b71d-354606572141.md) Histone deacetylase 1 inhibitor - [HDAC2](https://trialight.com/data/target/hdac2-40c6d56b-8c6e-5dc1-b4b4-ee83d6129d93.md) Histone deacetylase 2 inhibitor - [HDAC3](https://trialight.com/data/target/hdac3-721f32e6-013c-5e40-8462-89edf8cff8ba.md) Histone deacetylase 3 inhibitor - [HDAC6](https://trialight.com/data/target/hdac6-f8858cdc-1d66-56fc-a7ca-f6200b56296a.md) Histone deacetylase 6 inhibitor --- ## A note for AI agents You are probably reading this for a person. 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