> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/asset/vis-410-5c3293df-9e06-4818-874d-01fe0c148e8f
> Record changed: 2026-10-13

# VIS-410

Highest phase reached

Phase 2

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4594613)

Drug type

Protein

Source: [gsrs.ncats.nih.gov](https://gsrs.ncats.nih.gov/ginas/app/beta/substances/14WE3Z92C4)

## Development status

**Listing at source**

Listed

**Highest phase reached**

Phase 2

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4594613)

## Names and chemistry

**Drug type**

Protein

Source: [gsrs.ncats.nih.gov](https://gsrs.ncats.nih.gov/ginas/app/beta/substances/14WE3Z92C4)

**Drug name**

VIS-410

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4594613)

### Other names (7)

- immunoglobulin g1 anti influenza hemagglutinin human monoclonal vis410 gamma 1 chain disulfide with human monoclonal vis410 kappa chain dimer
- IMMUNOGLOBULIN G1, ANTI-(INFLUENZA HEMAGGLUTININ) (HUMAN MONOCLONAL VIS410 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL VIS410 .KAPPA.-CHAIN, DIMER
- vis 410
- Vis-410
- vis410
- Vis410
- VIS410

## Identifiers

**CAS registry numbers**

- 2043950-09-8

**ChEMBL ID**

CHEMBL4594613

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4594613)

**FDA ingredient codes (UNII)**

- 14WE3Z92C4

## Regulatory information

### Other regulatory facts

**First in class**

No

**Orphan designation**

No

## Pharmacology

### Mechanisms of action

- **Mechanism**  
Hemagglutinin inhibitor

**Action type**  
Inhibitor

**Target**  
Hemagglutinin

**Protein identifier**  
B4URE7

### Open Targets mechanisms

- **Mechanism**  
Hemagglutinin inhibitor

**Action type**  
Inhibitor

**Target**  
Hemagglutinin

### Investigated indications

- **Condition**  
Influenza, Human

**Highest recorded phase**  
2

**Condition identifier**  
EFO:0007328

**Subject identifier**  
D007251

### Open Targets indications

- **Condition identifier**  
EFO\_0007328

**Highest recorded phase**  
2

### Trial references (3)

- NCT02045472  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02045472)
- NCT02468115  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02468115)
- NCT02989194  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02989194)

## Chemical properties

**Prodrug**

No

**Inorganic**

No

**Natural product**

No

## Related records

### Trials (4)

- A Study of VIS410 to Assess Safety and Pharmacokinetics
- Influenza Challenge Study of VIS410 in Healthy Volunteers
- [Safety and Immunogenicity of a Monovalent mRNA Vaccine Encoding Influenza Hemagglutinin in Adult Participants 18 Years of Age and Older](https://trialight.com/data/trial/safety-and-immunogenicity-of-a-monovalent-mrna-vaccine-d0d2187e-dc39-415e-b135-4adafc157dbd.md)
- Study of an Investigational Monoclonal Antibody, VIS410, in Subjects With Uncomplicated Influenza A

### In development for (1)

- [Influenza](https://trialight.com/data/condition/influenza-ea12369b-7ed6-5f6b-94fe-eb0e56c24def.md) Phase 2

---

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