> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/asset/varicella-zoster-virus-live-attenuated-34054988-4238-421f-84ce-130d3d01633d
> Record changed: 2026-11-04

# Varicella zoster virus, live attenuated

Highest phase reached

Approved

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068357)

Drug type

Vaccine component

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068357)

First approval year

2006

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068357)

## Development status

**First approval year**

2006

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068357)

**Listing at source**

Listed

**Highest phase reached**

Approved

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068357)

## Names and chemistry

**Drug type**

Vaccine component

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068357)

**Drug name**

Varicella zoster virus, live attenuated

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068357)

### Brand names (4)

- varicella zoster virus live attenuated component of proquad
- Varicella zoster virus, live attenuated component of proquad
- zostavax
- Zostavax

### Other names (8)

- varicella zoster virus live attenuated
- varicella zoster virus vaccine zostavax
- Varicella zoster virus, live attenuated
- zostavax
- zostavax concomitant
- zostavax live attenuated herpes zoster vaccine
- zostavax nonconcomitant
- zoster vaccine live zostavax

## Identifiers

**ATC classification codes**

- J07BK01

Sources for recorded values

Source: [mor.nlm.nih.gov](https://mor.nlm.nih.gov/RxNav/search?searchBy=RXCUI&searchTerm=1292422)

**ChEMBL ID**

CHEMBL6068357

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068357)

**RxNorm IDs (RxCUI)**

- 1292422

## Regulatory information

### Other regulatory facts

**First in class**

No

**Orphan designation**

No

## Pharmacology

### Drug classification

**Drug name stem**

vir-

### Investigated indications (2)

- **Condition**  
Vaccination

**Highest recorded phase**  
4

**Condition identifier**  
EFO:0004292

**Subject identifier**  
D014611
- **Condition**  
Chickenpox

**Highest recorded phase**  
4

**Condition identifier**  
EFO:0007204

**Subject identifier**  
D002644

### Open Targets indications (7)

- **Condition identifier**  
EFO\_0000540
- **Condition identifier**  
EFO\_0006509
- **Condition identifier**  
EFO\_0006510

**Highest recorded phase**  
3
- **Condition identifier**  
EFO\_0007204
- **Condition identifier**  
MONDO\_0005608

**Highest recorded phase**  
4
- **Condition identifier**  
MONDO\_0005609
- **Condition identifier**  
MONDO\_0007915

**Highest recorded phase**  
1

### Reported adverse events (76)

- **Event**  
allergy to vaccine

**Reports**  
12

**Reporting signal score**

83.649
- **Event**  
alopecia

**Reports**  
56

**Reporting signal score**

119.631
- **Event**  
antibody test negative

**Reports**  
2

**Reporting signal score**

10.4966
- **Event**  
arthritis

**Reports**  
17

**Reporting signal score**

26.9295
- **Event**  
cataract

**Reports**  
8

**Reporting signal score**

9.74418
- **Event**  
cerebral small vessel ischaemic disease

**Reports**  
2

**Reporting signal score**

7.87476
- **Event**  
cervical radiculopathy

**Reports**  
2

**Reporting signal score**

7.76685
- **Event**  
condition aggravated

**Reports**  
24

**Reporting signal score**

14.1642
- **Event**  
diarrhoea

**Reports**  
34

**Reporting signal score**

10.3834
- **Event**  
disseminated varicella zoster vaccine virus infection

**Reports**  
2

**Reporting signal score**

11.5029
- **Event**  
drug intolerance

**Reports**  
63

**Reporting signal score**

139.802
- **Event**  
drug tolerance decreased

**Reports**  
12

**Reporting signal score**

53.2593
- **Event**  
dyslipidaemia

**Reports**  
4

**Reporting signal score**

8.86439
- **Event**  
expired drug administered

**Reports**  
7

**Reporting signal score**

26.3452
- **Event**  
exposure via skin contact

**Reports**  
4

**Reporting signal score**

17.881
- **Event**  
extra dose administered

**Reports**  
7

**Reporting signal score**

16.3893
- **Event**  
facial paralysis

**Reports**  
4

**Reporting signal score**

7.80528
- **Event**  
fungal infection

**Reports**  
6

**Reporting signal score**

7.69966
- **Event**  
hepatic cyst

**Reports**  
3

**Reporting signal score**

7.9799
- **Event**  
hepatic haematoma

**Reports**  
3

**Reporting signal score**

12.679
- **Event**  
hepatitis b core antibody positive

**Reports**  
3

**Reporting signal score**

13.6957
- **Event**  
herpes zoster

**Reports**  
74

**Reporting signal score**

216.072
- **Event**  
herpes zoster cutaneous disseminated

**Reports**  
3

**Reporting signal score**

14.7653
- **Event**  
herpes zoster disseminated

**Reports**  
4

**Reporting signal score**

16.3958
- **Event**  
herpes zoster oticus

**Reports**  
2

**Reporting signal score**

7.8637

And 51 more, listed on the interactive page.

## Chemical properties

**Prodrug**

No

**Chirality**

Single enantiomer

**Inorganic**

No

**Natural product**

No

## Related records

### Trials (85)

- A Study of a Quadrivalent Meningococcal Tetanus Protein Conjugate Vaccine in Infants and Toddlers
- A Study of an Investigational Zoster Vaccine in Subjects With a History of Varicella (Chickenpox) Given Concomitantly With Another Vaccine (V211-011)
- A Study of Intradermal Administration of ZOSTAVAX™ (V211-051 AM2)
- A Study of MG1111 in Healthy Children
- A Study of ProQuad in Healthy 4 to 6 Year Old Children (V221-014)
- [A Study on the Immune Response and Safety of an Investigational Chickenpox Vaccine When Given to Healthy Children 12 to 15 Months of Age](https://trialight.com/data/trial/a-study-on-the-immune-response-and-safety-of-an-4e0951aa-7759-41a3-994c-3edbadddcf33.md)
- [A Study on the Immune Response and Safety of Various Potencies of an Investigational Chickenpox Vaccine Compared With a Marketed Chickenpox Vaccine, Given to Healthy Children 12 to 15 Months of Age](https://trialight.com/data/trial/a-study-on-the-immune-response-and-safety-of-various-51e7fb37-7cb5-46e7-93e7-98ba896a9d45.md)
- A Study on the Live-Attenuated Herpes Zoster Vaccine for Sequential Booster Immunization Following Recombinant Herpes Zoster Vaccine
- A Study to Evaluate Immunity to Varicella Zoster Virus After Immunization With V212 Vaccine or Zostavax (V212-003)
- A Study to Evaluate Safety, Tolerability, and Immunogenicity of an Investigational Zoster Vaccine In Subjects With a History of Varicella (Chickenpox)(V211-010)(COMPLETED)
- [A Trial to Evaluate the Lot-to-lot Consistency of Live Attenuated Varicella Vaccine in Healthy People 1-12 Years of Age](https://trialight.com/data/trial/a-trial-to-evaluate-the-lot-to-lot-consistency-of-live-9118a0f0-fe8c-46e9-88c2-acdf5ae29c88.md)
- An Immunity Persistence Study of Booster Dose of Live Attenuated Varicella Vaccine
- Analysis on AEFI Surveillance Data for Live Attenuated Varicella Vaccine
- Assessment of Immunogenicity of Zostavax® in Patients With Antibody Deficiency 60 Years of Age and Older
- Comparison of a Live Herpes Zoster Vaccine and a Recombinant Vaccine in 50-59 and 70-85 Year Olds
- Concomitant Use of Hepatitis A Vaccine With Measles, Mumps, Rubella and Varicella Vaccine and Pneumococcal 7-Valent Conjugate Vaccine in Healthy 12-Month-Old Children (V251-067)
- Effective Study of Live Attenuated Varicella Vaccine to Treat Severe Resistant Psoriasis
- Efficacy Trial of a Vaccine to Prevent Herpes Zoster in Adults Over 40 Years of Age
- Evaluation of Immunogenicity and Safety of VARIVAX™ New Seed Process (NSP) in Children (V210-063)
- Frozen ProQuad Administered Concomitantly Versus Nonconcomitantly With Other Pediatric Vaccines

### Approved for (2)

- [Chickenpox](https://trialight.com/data/condition/chickenpox-4213f806-c779-5b01-9e52-7179e9edebeb.md)
- [Varicella zoster infection](https://trialight.com/data/condition/varicella-zoster-infection-8bfd714d-2964-5abf-b7ab-66dea5fe7146.md)

### In development for (1)

- [Systemic lupus erythematosus](https://trialight.com/data/condition/systemic-lupus-erythematosus-6c9d074f-cc5f-588b-bf0c-6338d30c6eac.md) Phase 1

### Other linked conditions (2)

- [Herpes zoster](https://trialight.com/data/condition/herpes-zoster-b5c04cf4-ae28-5154-8254-f4f1fde4c3c9.md)
- [Immune system disorder](https://trialight.com/data/condition/immune-system-disorder-24846188-b462-515c-bb34-142255a648c8.md)

---

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