Varicella zoster virus envelope glycoprotein E

Highest phase reached
Drug type
Vaccine component
First approval year

First approval year
Listing at source
Listed
Highest phase reached

Drug type
Vaccine component
Drug name
Varicella zoster virus envelope glycoprotein E

  • shingrix
  • Shingrix

  • gsk 1437173a
  • GSK 1437173A
  • Gsk-1437173a
  • Herpes Zoster vaccine (GSK1437173A)
  • herpes zoster vaccine gsk1437173a
  • Herpes zoster vaccine gsk1437173a
  • Herpes zoster vaccine GSK1437173A
  • Herpes Zoster vaccine GSK1437173A
  • Herpes Zoster Vaccine GSK1437173A
  • Recombinant Herpes Zoster Vaccine (Shingrix)
  • Recombinant varicella zoster virus (vzv) glycoprotein e
  • recombinant varicella zoster virus vzv glycoprotein e
  • Recombinant zoster vaccine adjuvanted (SHINGRIX)
  • shingrix
  • Shingrix
  • SHINGRIX
  • Shingrix®
  • SHINGRIX®
  • varicella zoster virus envelope glycoprotein e
  • Varicella zoster virus envelope glycoprotein e

ChEMBL ID
CHEMBL4297975

First in class
No
Orphan designation
No

Drug name stem
vir-

Mechanisms of action

  • Mechanism
    Envelope glycoprotein E vaccine antigen
    Action type
    VACCINE_ANTIGEN
    Target
    Envelope glycoprotein E
    Protein identifier
    Q9J3M8

Open Targets mechanisms

  • Mechanism
    Envelope glycoprotein E vaccine antigen
    Action type
    VACCINE ANTIGEN
    Target
    Envelope glycoprotein E

  • Condition
    Respiratory Tract Diseases
    Highest recorded phase
    2
    Condition identifier
    EFO:0000684
    Subject identifier
    D012140
  • Condition
    Vaccination
    Highest recorded phase
    4
    Condition identifier
    EFO:0004292
    Subject identifier
    D014611
  • Condition
    Herpes Zoster
    Highest recorded phase
    4
    Condition identifier
    EFO:0006510
    Subject identifier
    D006562

  • Condition identifier
    EFO_0000684
    Highest recorded phase
    2
  • Condition identifier
    EFO_0001068
    Highest recorded phase
    3
  • Condition identifier
    EFO_0006509
    Highest recorded phase
    1
  • Condition identifier
    EFO_0006510
  • Condition identifier
    MONDO_0005136
    Highest recorded phase
    3
  • Condition identifier
    MONDO_0005609
    Highest recorded phase
    4

  • Event
    affective disorder
    Reports
    2
    Reporting signal score
    6.50143
  • Event
    aortitis
    Reports
    2
    Reporting signal score
    10.9066
  • Event
    arthralgia
    Reports
    7
    Reporting signal score
    6.39882
  • Event
    borrelia infection
    Reports
    2
    Reporting signal score
    12.0225
  • Event
    bowel movement irregularity
    Reports
    2
    Reporting signal score
    7.56817
  • Event
    diverticulitis
    Reports
    3
    Reporting signal score
    6.97396
  • Event
    encephalitis
    Reports
    2
    Reporting signal score
    6.41887
  • Event
    feeling hot
    Reports
    3
    Reporting signal score
    6.01757
  • Event
    herpes zoster
    Reports
    11
    Reporting signal score
    31.365
  • Event
    herpes zoster cutaneous disseminated
    Reports
    4
    Reporting signal score
    28.3095
  • Event
    herpes zoster reactivation
    Reports
    2
    Reporting signal score
    14.0446
  • Event
    immunodeficiency
    Reports
    3
    Reporting signal score
    11.098
  • Event
    inflammation
    Reports
    4
    Reporting signal score
    9.07666
  • Event
    joint swelling
    Reports
    4
    Reporting signal score
    5.65811
  • Event
    macular degeneration
    Reports
    2
    Reporting signal score
    6.47833
  • Event
    micturition urgency
    Reports
    3
    Reporting signal score
    10.3408
  • Event
    myalgia
    Reports
    5
    Reporting signal score
    6.00497
  • Event
    ophthalmic herpes zoster
    Reports
    2
    Reporting signal score
    8.97016
  • Event
    oropharyngeal pain
    Reports
    4
    Reporting signal score
    7.06276
  • Event
    osteoarthritis
    Reports
    3
    Reporting signal score
    6.23658
  • Event
    pain
    Reports
    14
    Reporting signal score
    19.1861
  • Event
    pain of skin
    Reports
    4
    Reporting signal score
    14.8685
  • Event
    peripheral swelling
    Reports
    6
    Reporting signal score
    9.56977
  • Event
    photophobia
    Reports
    3
    Reporting signal score
    8.89227
  • Event
    pneumonia
    Reports
    9
    Reporting signal score
    11.5476

And 17 more, listed on the interactive page.

And 4 more, listed on the interactive page.

Prodrug
No
Chirality
Single enantiomer
Inorganic
No
Natural product
No

Related records

Trials (72)

Approved for (1)

In development for (3)