> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/asset/typhoid-vi-polysaccharide-vaccine-55297838-7e36-4406-90fd-42ce464987d8
> Record changed: 2026-11-04

# Typhoid VI polysaccharide vaccine

Highest phase reached

Phase 3

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2108822)

Drug type

Vaccine component

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2108822)

## Development status

**Listing at source**

Listed

**Highest phase reached**

Phase 3

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2108822)

## Names and chemistry

**Drug type**

Vaccine component

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2108822)

**Drug name**

Typhoid VI polysaccharide vaccine

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2108822)

### Other names (29)

- bacillus typhi
- Bacillus typhi
- salmonella choleraesuis typhi
- Salmonella choleraesuis typhi
- salmonella enterica ser typhi
- Salmonella enterica ser. typhi
- salmonella enterica serovar typhi
- Salmonella enterica serovar typhi
- salmonella typhi
- Salmonella typhi
- Salmonella Typhi
- salmonella typhi vectored pneumonia vaccine
- Salmonella Typhi-vectored pneumonia vaccine
- salmonella typhimurium
- Salmonella typhimurium
- Salmonella Typhimurium
- salmonella typhosa
- Salmonella typhosa
- Ty800 (Salmonella typhi) Oral Vaccine
- ty800 salmonella typhi oral vaccine
- typhoid vaccine
- Typhoid vaccine
- Typhoid Vaccine
- typhoid vaccine antigens
- Typhoid vaccine antigens

And 4 more, listed on the interactive page.

## Identifiers

**ChEMBL ID**

CHEMBL2108822

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2108822)

**RxNorm IDs (RxCUI)**

- 807219

## Regulatory information

### Other regulatory facts

**First in class**

No

**Orphan designation**

No

## Pharmacology

### Investigated indications (2)

- **Condition**  
Malaria

**Highest recorded phase**  
2

**Condition identifier**  
EFO:0001068

**Subject identifier**  
D008288
- **Condition**  
Hepatitis A

**Highest recorded phase**  
3

**Condition identifier**  
EFO:0007305

**Subject identifier**  
D006506

### Open Targets indications (15)

- **Condition identifier**  
EFO\_0000195
- **Condition identifier**  
EFO\_0000319

**Highest recorded phase**  
1
- **Condition identifier**  
EFO\_0001068

**Highest recorded phase**  
2
- **Condition identifier**  
EFO\_0001358
- **Condition identifier**  
EFO\_0007305

**Highest recorded phase**  
3
- **Condition identifier**  
EFO\_0009429
- **Condition identifier**  
EFO\_0009429

**Highest recorded phase**  
4
- **Condition identifier**  
EFO\_0600064

**Highest recorded phase**  
1
- **Condition identifier**  
EFO\_1001418

**Highest recorded phase**  
4
- **Condition identifier**  
HP\_0100806

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0002009

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0002050

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0004992

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0006502

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0043905

**Highest recorded phase**  
1

### Reported adverse events (2)

- **Event**  
abortion

**Reports**  
3

**Reporting signal score**

16.632
- **Event**  
urticaria chronic

**Reports**  
3

**Reporting signal score**

21.8683

### Trial references (2)

- NCT00197249  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00197249)
- NCT03917654  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03917654)

## Chemical properties

**Prodrug**

No

**Chirality**

Single enantiomer

**Inorganic**

No

**Natural product**

No

## Related records

### Trials (47)

- A Phase 3b, Randomized, Open-Label Study to Evaluate the Safety and Immunogenicity of Select Travel Vaccines When Administered Concomitantly With MenACWY in Adults
- A Study on the Immune Response and Safety of a Multicomponent Shigella Vaccine in Preventing Shigellosis in Infants
- A Study to Evaluate Safety, Reactogenicity, and Immune Response of GVGH iNTS-TCV Vaccine Against Invasive Nontyphoidal Salmonella and Typhoid Fever
- [A Study to Evaluate Safety, Reactogenicity, and Immune Response of GVGH iNTS-TCV Vaccine Against Invasive Nontyphoidal Salmonella Disease and Typhoid Fever in Infants](https://trialight.com/data/trial/a-study-to-evaluate-safety-reactogenicity-and-immune-e71b2924-2aba-4229-b641-f00520504789.md)
- Challenge Non-Typhoidal Salmonella (CHANTS) Study
- Cognitive, Emotional, and Neural Responses to Acute Inflammation
- Combined Vi Vaccination and Health Education Program on the Burden of Typhoid in Childhood
- Cross-reactive Immunity Elicited by Oral and Parenteral Typhoid Vaccines
- CVD 909 Vi Prime Boost Study
- Effect of Age and Fitness on Vascular Function and Oxidative Stress During Acute Inflammation
- Effects of Oral Iron Supplementation Before vs at Time of Vaccination on Immune Response in Iron Deficient Kenyan Women
- Effects of Oral Iron Supplementation on Vaccine Response in Iron Deficient Kenyan Women
- Evaluation of the Vi Polysaccharide Vaccine Against Typhoid Fever
- IL-2 Expressing, Attenuated Salmonella Typhimurium in Unresectable Hepatic Spread
- Immune Equivalence Between Multi-dose and Single Dose Formulation of Vi-DT and Their Overall Safety (Phase III)
- Immunogenicity and Safety of Vi-DT (Diphtheria Toxoid) Typhoid Conjugate Vaccine (Phase III)
- Immunogenicity and Tolerability of Booster Typhoid Conjugate Vaccine (TCV) 5-6 Years After Initial Dose in Children in Burkina Faso
- Inflammation and Threat Sensitivity in PTSD
- Inflammatory Challenge and Fear
- Influence of Dietary Nitrate on Vascular Dysfunction and Inflammation

### In development for (8)

- Acute respiratory distress syndrome Phase 1
- [Cancer](https://trialight.com/data/condition/cancer-703b1dfc-4812-50eb-83f4-d7a205d16bdb.md) Phase 1
- [Cardiovascular disorder](https://trialight.com/data/condition/cardiovascular-disorder-362e433e-88a4-575f-90af-50fe7239dec0.md) Phase 1
- [Depressive disorder](https://trialight.com/data/condition/depressive-disorder-7618feda-3f90-5521-94e1-99f7100e8324.md) Phase 1
- Hepatitis A virus infection Phase 3
- [Major depressive disorder](https://trialight.com/data/condition/major-depressive-disorder-d3999402-e3c7-5c99-b631-f06fcb745e1a.md) Phase 1
- [Malaria](https://trialight.com/data/condition/malaria-54828cac-9b96-5833-93e2-e012d4505853.md) Phase 2
- Pneumonitis Phase 1

### Other linked conditions (1)

- Post-traumatic stress disorder

---

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