Tozinameran

Highest phase reached
Drug type
Vaccine component
First approval year

First approval year
Listing at source
Listed
Highest phase reached

Drug type
Vaccine component
Drug name
Tozinameran

  • comirnaty
  • Comirnaty

  • bnt 162b2
  • BNT-162B2
  • bnt162b2
  • Bnt162b2
  • BNT162b2
  • BNT162B2
  • BNT162b2 (B.1.1.529)
  • BNT162b2 (B.1.351)
  • BNT162b2 (Omi JN.1)
  • BNT162b2 (Omi KP.2)
  • BNT162b2 (Omi XBB.1.5)
  • BNT162b2 (Tozinameran)
  • BNT162b2 20mcg
  • BNT162b2 30mcg
  • BNT162b2 30μg
  • BNT162b2.B.1.351
  • comirnaty
  • Comirnaty
  • COMIRNATY
  • Comirnaty (BTN162b2)
  • COMIRNATY intramuscular injection
  • comirnaty mrna
  • Comirnaty mrna
  • Comirnaty®
  • COMIRNATY®

And 19 more, listed on the interactive page.

CAS registry numbers
  • 2417899-77-3
ChEMBL ID
CHEMBL4650429
RxNorm IDs (RxCUI)
  • 2468230
FDA ingredient codes (UNII)
  • 5085ZFP6SJ

First in class
No
Orphan designation
No

Drug name stem
-meran

Mechanisms of action

  • Mechanism
    Spike glycoprotein vaccine antigen
    Action type
    VACCINE_ANTIGEN
    Target
    Spike glycoprotein
    Protein identifier
    P0DTC2

Open Targets mechanisms

  • Mechanism
    Spike glycoprotein vaccine antigen
    Action type
    VACCINE ANTIGEN
    Target
    Spike glycoprotein

  • Condition
    Infections
    Highest recorded phase
    2
    Condition identifier
    EFO:0000544
    Subject identifier
    D007239
  • Condition
    Severe Acute Respiratory Syndrome
    Highest recorded phase
    4
    Condition identifier
    EFO:0000694
    Subject identifier
    D045169
  • Condition
    Vaccination
    Highest recorded phase
    4
    Condition identifier
    EFO:0004292
    Subject identifier
    D014611
  • Condition
    Neoplasms
    Highest recorded phase
    2
    Condition identifier
    MONDO:0004992
    Subject identifier
    D009369
  • Condition
    Hypersensitivity
    Highest recorded phase
    2
    Condition identifier
    MONDO:0005271
    Subject identifier
    D006967
  • Condition
    COVID-19
    Highest recorded phase
    4
    Condition identifier
    MONDO:0100096
    Subject identifier
    D000086382
  • Condition
    Severe Acute Respiratory Syndrome
    Highest recorded phase
    4
    Condition identifier
    MONDO:0100096
    Subject identifier
    D045169

  • Condition identifier
    EFO_0000694
    Highest recorded phase
    3
  • Condition identifier
    MONDO_0001056
    Highest recorded phase
    1
  • Condition identifier
    MONDO_0002974
  • Condition identifier
    MONDO_0004952
    Highest recorded phase
    1
  • Condition identifier
    MONDO_0004992
    Highest recorded phase
    1
  • Condition identifier
    MONDO_0004992
    Highest recorded phase
    2
  • Condition identifier
    MONDO_0005062
    Highest recorded phase
    1
  • Condition identifier
    MONDO_0005100
    Highest recorded phase
    2
  • Condition identifier
    MONDO_0005109
  • Condition identifier
    MONDO_0005192
    Highest recorded phase
    1
  • Condition identifier
    MONDO_0005265
  • Condition identifier
    MONDO_0005271
    Highest recorded phase
    2
  • Condition identifier
    MONDO_0005301
    Highest recorded phase
    2
  • Condition identifier
    MONDO_0005554
    Highest recorded phase
    1
  • Condition identifier
    MONDO_0005575
  • Condition identifier
    MONDO_0006594
    Highest recorded phase
    2
  • Condition identifier
    MONDO_0007243
    Highest recorded phase
    1
  • Condition identifier
    MONDO_0007254
  • Condition identifier
    MONDO_0007256
    Highest recorded phase
    1
  • Condition identifier
    MONDO_0007915
    Highest recorded phase
    2
  • Condition identifier
    MONDO_0008054
    Highest recorded phase
    2
  • Condition identifier
    MONDO_0008315
  • Condition identifier
    MONDO_0008383
    Highest recorded phase
    2
  • Condition identifier
    MONDO_0009831
    Highest recorded phase
    1
  • Condition identifier
    MONDO_0011429
    Highest recorded phase
    2

And 6 more, listed on the interactive page.

  • Event
    acute macular neuroretinopathy
    Reports
    2
    Reporting signal score
    12.0859
  • Event
    bicytopenia
    Reports
    9
    Reporting signal score
    32.0033
  • Event
    catarrh
    Reports
    3
    Reporting signal score
    12.2123
  • Event
    cerebral venous thrombosis
    Reports
    11
    Reporting signal score
    39.9965
  • Event
    covid-19
    Reports
    16
    Reporting signal score
    18.0666
  • Event
    covid-19 pneumonia
    Reports
    24
    Reporting signal score
    87.7176
  • Event
    cutaneous lupus erythematosus
    Reports
    7
    Reporting signal score
    20.495
  • Event
    deep vein thrombosis
    Reports
    17
    Reporting signal score
    12.7557
  • Event
    ear pruritus
    Reports
    4
    Reporting signal score
    11.0627
  • Event
    gravitational oedema
    Reports
    4
    Reporting signal score
    13.5915
  • Event
    hepatic cytolysis
    Reports
    12
    Reporting signal score
    37.4803
  • Event
    idiopathic inflammatory myopathy
    Reports
    2
    Reporting signal score
    15.0172
  • Event
    immune thrombocytopenia
    Reports
    16
    Reporting signal score
    62.3939
  • Event
    ischaemic stroke
    Reports
    29
    Reporting signal score
    66.5488
  • Event
    jugular vein thrombosis
    Reports
    5
    Reporting signal score
    15.2547
  • Event
    myocarditis
    Reports
    13
    Reporting signal score
    29.7395
  • Event
    myositis
    Reports
    7
    Reporting signal score
    11.7451
  • Event
    ophthalmic herpes zoster
    Reports
    5
    Reporting signal score
    15.2547
  • Event
    pancreatitis acute
    Reports
    10
    Reporting signal score
    10.6669
  • Event
    pericarditis
    Reports
    10
    Reporting signal score
    17.5988
  • Event
    petechiae
    Reports
    8
    Reporting signal score
    14.2961
  • Event
    piloerection
    Reports
    4
    Reporting signal score
    15.3661
  • Event
    portosplenomesenteric venous thrombosis
    Reports
    2
    Reporting signal score
    11.0349
  • Event
    pulmonary embolism
    Reports
    59
    Reporting signal score
    100.697
  • Event
    pyrexia
    Reports
    42
    Reporting signal score
    16.1793

And 12 more, listed on the interactive page.

And 36 more, listed on the interactive page.

Prodrug
No
Chirality
Single enantiomer
Inorganic
No
Natural product
No

Related records

Trials (142)

Approved for (2)

In development for (2)