> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/asset/thyroid-d9eaadc2-7fbf-41b3-b1e5-ddbb99272083 > Record changed: 2026-10-13 # Thyroid Highest phase reached Phase 3 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2108878) Drug type Unknown ## Development status **Listing at source** Listed **Highest phase reached** Phase 3 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2108878) ## Names and chemistry **Drug type** Unknown **Drug name** Thyroid Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2108878) ### Brand names (2) - nature - Nature ### Other names (45) - armour thyroid - Armour thyroid - Armour Thyroid - Armour® Thyroid - dessicated thyroid - Dessicated thyroid - dried thyroid - Dried thyroid - glandula thyreoidea suis - Glandula thyreoidea suis - Nature-based materials - nsc 26492 - NSC-26492 - pig thyroid - Pig thyroid - porcine thyroid - Porcine thyroid - pork thyroid - Pork thyroid - sus scrofa thyroid - Sus scrofa thyroid - thyreoidea suis - Thyreoidea suis - thyroid - Thyroid And 20 more, listed on the interactive page. ## Identifiers **ATC classification codes** - H03AA05 Sources for recorded values Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2108878) **CAS registry numbers** - 8028-36-2 **ChEMBL ID** CHEMBL2108878 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2108878) **FDA ingredient codes (UNII)** - 6RV024OAUQ ### RxNorm IDs (RxCUI) (2) - 10572 - 235479 ## Regulatory information ### Other regulatory facts **First in class** No **Orphan designation** No ## Pharmacology ### Drug classification **Pharmacology name** TSH **Type** Peptide ### Investigated indications (5) - **Condition** Down Syndrome **Highest recorded phase** 3 **Condition identifier** EFO:0001064 **Subject identifier** D004314 - **Condition** Heart Failure **Highest recorded phase** 3 **Condition identifier** EFO:0003144 **Subject identifier** D006333 - **Condition** Hypothyroidism **Highest recorded phase** 2 **Condition identifier** EFO:0004705 **Subject identifier** D007037 - **Condition** Thyroid Neoplasms **Highest recorded phase** 3 **Condition identifier** MONDO:0002108 **Subject identifier** D013964 - **Condition** Diabetes Mellitus, Type 2 **Highest recorded phase** 1 **Condition identifier** MONDO:0005148 **Subject identifier** D003924 ### Open Targets indications (5) - **Condition identifier** EFO\_0001064 **Highest recorded phase** 3 - **Condition identifier** EFO\_0003144 **Highest recorded phase** 3 - **Condition identifier** EFO\_0004705 - **Condition identifier** MONDO\_0002108 **Highest recorded phase** 3 - **Condition identifier** MONDO\_0005420 **Highest recorded phase** 2 ### Warnings - **Warning** Black Box Warning ### Open Targets warnings - **Warning** Black Box Warning **Country** United States ### Reported adverse events (29) - **Event** acute myeloid leukaemia **Reports** 14 **Reporting signal score** 30.8421 - **Event** anaemia **Reports** 38 **Reporting signal score** 18.1465 - **Event** blast cell count increased **Reports** 6 **Reporting signal score** 21.9041 - **Event** blood thyroid stimulating hormone decreased **Reports** 6 **Reporting signal score** 14.9237 - **Event** blood thyroid stimulating hormone increased **Reports** 7 **Reporting signal score** 13.8075 - **Event** bone cyst **Reports** 5 **Reporting signal score** 16.9163 - **Event** bone marrow failure **Reports** 13 **Reporting signal score** 15.5466 - **Event** dehydration **Reports** 33 **Reporting signal score** 26.0625 - **Event** eye infection **Reports** 9 **Reporting signal score** 19.0997 - **Event** febrile neutropenia **Reports** 108 **Reporting signal score** 254.41 - **Event** gastric outlet obstruction **Reports** 3 **Reporting signal score** 17.5209 - **Event** gonadotrophin deficiency **Reports** 4 **Reporting signal score** 25.4052 - **Event** hepatic function abnormal **Reports** 39 **Reporting signal score** 74.1093 - **Event** laryngeal inflammation **Reports** 4 **Reporting signal score** 19.0279 - **Event** liver disorder **Reports** 16 **Reporting signal score** 17.7866 - **Event** myelosuppression **Reports** 37 **Reporting signal score** 109.1 - **Event** nail growth abnormal **Reports** 5 **Reporting signal score** 20.1528 - **Event** neutrophil count decreased **Reports** 33 **Reporting signal score** 54.9422 - **Event** oesophagitis **Reports** 21 **Reporting signal score** 50.8389 - **Event** pancytopenia **Reports** 18 **Reporting signal score** 15.1687 - **Event** pharyngeal inflammation **Reports** 4 **Reporting signal score** 14.2616 - **Event** platelet count decreased **Reports** 60 **Reporting signal score** 84.686 - **Event** pneumonia **Reports** 53 **Reporting signal score** 33.1673 - **Event** pyrexia **Reports** 62 **Reporting signal score** 33.1031 - **Event** radiation oesophagitis **Reports** 7 **Reporting signal score** 32.0777 And 4 more, listed on the interactive page. ### Trial references (6) - NCT00435851 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00435851) - NCT01557504 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01557504) - NCT01576705 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01576705) - NCT02656329 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02656329) - NCT05384847 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05384847) - NCT06345339 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06345339) ## Chemical properties **Prodrug** No **Chirality** Single enantiomer **Inorganic** No **Natural product** No ## National Drug Codes - 0456-0458 - 0456-0459 - 0456-0460 - 0456-0461 - 0456-0462 - 0456-0463 - 0456-0464 - 0456-1045 - 62559-740 - 62559-741 - 62559-742 - 62559-743 - 62559-744 - 69680-165 - 69680-166 - 69680-167 - 69680-168 - 69680-169 - 75834-310 - 75834-311 - 75834-312 - 75834-313 - 75834-314 - 75834-315 - 75834-316 And 15 more, listed on the interactive page. ## Related records ### Trials (18) - A Study of Armour® Thyroid Compared to Synthetic T4 (Levothyroxine) in Previously Hypothyroid Participants - A Study to Assess the Pharmacokinetics and the Ability for Pediatric Participants With Type 2 Diabetes to Swallow MK-0431A XR Tablets (MK-0431A-296) - [A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants](https://trialight.com/data/trial/a-study-to-assess-the-safety-and-efficacy-of-oral-armour-7d3645f2-766a-449b-9d76-575c4384a231.md) - An Exploratory Study on NK Cell-assisted Prevention of Bone Marrow Suppression During Chemotherapy for Ovarian Cancer - An Open-Label, Single-Arm Study to Investigate the Efficacy and Safety of North Star Desiccated Porcine Thyroid Extract Tablets. - Biodiversity Intervention and Atopic Sensitization - Desiccated Thyroid Extract and Levothyroxine for Hypothyroidism Treatment - Desiccated Thyroid Extract Combined With Levothyroxine for TSH Suppression Therapy in DTC - Desiccated Thyroid Extract Versus Synthetic T3/T4 Combination (ThyrolarTM) Versus L-T4 Alone in the Therapy of Primary Hypothyroidism With Special Attention to the Gene Polymorphism - Effect of Exergaming Exercises and Mediterranean Diet on Thyroid Cancer Patients Following Total Thyroidectomy - Effects of Triiodothyronine (T3) in Ischemic Heart Failure - Efficacy Assessment of Systematic Treatment With Folinic Acid and Thyroid Hormone on Psychomotor Development of Down Syndrome Young Children - International Study to Determine if AdreView Heart Function Scan Can be Used to Identify Patients With Mild or Moderate Heart Failure (HF) That Benefit From Implanted Medical Device - Medico-Economic Comparison of Four Strategies of Radioiodine Ablation in Thyroid Carcinoma Patients - Safety and Efficacy of Intraperitoneal Injection of METR-NK Cells as Neoadjuvant Therapy for Advanced Epithelial Ovarian Cancer - The Analysis of Thyroidectomy and Parathyroidectomy - The Effectiveness of Natural Resources for Reducing Stress - Vapocoolant Spray Used Prior to Intravenous (IV) Insertions ### In development for (5) - [Down syndrome](https://trialight.com/data/condition/down-syndrome-6624b8ac-2317-5aff-9950-8c418c3c46bf.md) Phase 3 - [Heart failure](https://trialight.com/data/condition/heart-failure-e230b1c3-ce91-5f80-b80f-81fc353ce5cc.md) Phase 3 - [Hypothyroidism](https://trialight.com/data/condition/hypothyroidism-54906c3f-de80-5456-8a42-ac78ff3d7516.md) Phase 2 - [Thyroid cancer](https://trialight.com/data/condition/thyroid-cancer-44afb6a8-b88e-5e18-b9fd-7b51661c2c23.md) Phase 3 - [Type 2 diabetes mellitus](https://trialight.com/data/condition/type-2-diabetes-mellitus-98e14a90-bb06-5174-90c7-901a0a259fb9.md) Phase 1 --- ## A note for AI agents You are probably reading this for a person. 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