> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/asset/sulfosalicylic-acid-94c617d3-c0f2-4810-9f79-fce72b1d95a8
> Record changed: 2026-10-13

# Sulfosalicylic acid

Drug type

Small molecule

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2107580)

## Development status

**Listing at source**

Listed

## Names and chemistry

**Drug type**

Small molecule

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2107580)

**Drug name**

Sulfosalicylic acid

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2107580)

**Molecular weight**

254.22

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2107580)

**Structure (SMILES)**

O.O.O=C(O)c1cc(S(=O)(=O)O)ccc1O

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2107580)

### Other names (16)

- 2 hydroxybenzoic 5 sulfonic acid dihydrate
- 2-HYDROXYBENZOIC-5-SULFONIC ACID DIHYDRATE
- 5 sulfosalicylic acid dihyrate
- 5-SULFOSALICYLIC ACID DIHYRATE
- benzoic acid 2 hydroxy 5 sulfo dihydrate
- benzoic acid 2 hydroxy 5 sulfo hydrate 1 2
- BENZOIC ACID, 2-HYDROXY-5-SULFO-, DIHYDRATE
- BENZOIC ACID, 2-HYDROXY-5-SULFO-, HYDRATE (1:2)
- nsc 190565
- NSC-190565
- salicylic acid 5 sulfo dihydrate
- SALICYLIC ACID, 5-SULFO-, DIHYDRATE
- sulfosalicylic acid
- Sulfosalicylic acid
- SULFOSALICYLIC ACID DIHYDRATE \[MI\]
- sulfosalicylic acid dihydrate mi

## Identifiers

**CAS registry numbers**

- 5965-83-3

**ChEMBL ID**

CHEMBL2107580

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2107580)

**InChIKey**

BHDKTFQBRFWJKR-UHFFFAOYSA-N

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2107580)

**PubChem compound IDs**

- 2723734

**FDA ingredient codes (UNII)**

- 09NGQ462S6

## Regulatory information

### Other regulatory facts

**First in class**

No

**Orphan designation**

No

## Pharmacology

### Drug classification

**Drug name stem**

\-fos-; -sal-

## Chemical properties

**Hydrogen bond acceptors**

4

**Hydrogen bond donors**

3

**Polar surface area**

111.9

**Calculated partition coefficient (ALogP)**

0.34

**Prodrug**

No

**Chirality**

Achiral

**Inorganic**

No

**Rule-of-five violations**

0

**Rotatable bonds**

2

**Heavy atoms**

16

**Molecular formula**

C7H10O8S

**Monoisotopic mass**

254.00963845

**Natural product**

No

## Evidence counts

**Recorded assays**

1

**Active assays**

0

## Related records

### Trials (7)

- [A Study Comparing Clindamycin Phosphate, Adapalene, and Benzoyl Peroxide Topical Gel 0.15%;3.1%;1.2% (Taro Pharmaceuticals U.S.A., Inc.) and CABTREO Topical Gel for the Treatment of Acne Vulgaris.](https://trialight.com/data/trial/a-study-comparing-clindamycin-phosphate-adapalene-and-ba9c70f3-fa12-4215-ac68-4e41d58205e0.md)
- Bioequivalence Study Comparing Clindamycin Phosphate (1.2%) and Tretinoin (0.025%) Topical Gel to Ziana and Placebo
- Cannabis, Neuroinflammation, and Suicidal Ideation: A Supplemental Brain Imaging Study
- Determination of the Optimal Dose of Ephedrine in Intraoperative Arterial Hypotension of Newborns and Infants up to 6 Months of Age.
- Evaluate Therapeutic Equivalence and Safety of Two Clindamycin Phosphate and Benzoyl Peroxide Gels in Acne Vulgaris
- Immunogenicity Study of the Recombinant Human Papillomavirus Virus Type 6/11 Bivalent Vaccine
- Study Comparing Clindamycin Phosphate and Benzoyl Peroxide Gel to Acanya® Gel and Both to a Vehicle Control in the Treatment of Acne Vulgaris

---

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