> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/asset/streptococcus-pneumoniae-polysaccharide-conjugated-to-897ce0bb-238e-4bfa-aefc-ea2671787774
> Record changed: 2026-11-04

# Streptococcus pneumoniae polysaccharide conjugated to tetanus toxoid

Highest phase reached

Approved

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068366)

Drug type

Vaccine component

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068366)

First approval year

2009

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068366)

## Development status

**First approval year**

2009

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068366)

**Listing at source**

Listed

**Highest phase reached**

Approved

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068366)

## Names and chemistry

**Drug type**

Vaccine component

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068366)

**Drug name**

Streptococcus pneumoniae polysaccharide conjugated to tetanus toxoid

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068366)

### Brand names (2)

- streptococcus pneumoniae polysaccharide conjugated to tetanus toxoid component of synflorix
- Streptococcus pneumoniae polysaccharide conjugated to tetanus toxoid component of synflorix

### Other names (2)

- streptococcus pneumoniae polysaccharide conjugated to tetanus toxoid
- Streptococcus pneumoniae polysaccharide conjugated to tetanus toxoid

## Identifiers

**ChEMBL ID**

CHEMBL6068366

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068366)

## Regulatory information

### Other regulatory facts

**First in class**

No

**Orphan designation**

No

## Pharmacology

### Mechanisms of action

- **Mechanism**  
Polysaccharide conjugated to Tetanus toxoid vaccine antigen

**Action type**  
VACCINE\_ANTIGEN

**Target**  
Polysaccharide conjugated to Tetanus toxoid

### Investigated indications (2)

- **Condition**  
Pneumococcal Infections

**Highest recorded phase**  
4

**Condition identifier**  
EFO:0000772

**Subject identifier**  
D011008
- **Condition**  
Vaccination

**Highest recorded phase**  
4

**Condition identifier**  
EFO:0004292

**Subject identifier**  
D014611

### Open Targets indications (2)

- **Condition identifier**  
EFO\_1001476

**Highest recorded phase**  
3
- **Condition identifier**  
MONDO\_0005114

**Highest recorded phase**  
4

## Chemical properties

**Prodrug**

No

**Chirality**

Single enantiomer

**Inorganic**

No

**Natural product**

No

## Related records

### Trials (63)

- A Phase 3 Study to Evaluate the Immunogenicity and Safety of Walvax's PCV13-TT as Compared to Pfizer's PCV13
- [A Study on the Immune Response and Safety of an Investigational Chickenpox Vaccine and a Marketed Measles, Mumps and Rubella Vaccine When Administered as Intramuscular Injection to Healthy Children 12 to 15 Months of Age](https://trialight.com/data/trial/a-study-on-the-immune-response-and-safety-of-an-e1b18297-6856-4593-85d5-f9945e920af0.md)
- [A Study on the Immune Response and Safety of an Investigational Chickenpox Vaccine When Given to Healthy Children 12 to 15 Months of Age](https://trialight.com/data/trial/a-study-on-the-immune-response-and-safety-of-an-4e0951aa-7759-41a3-994c-3edbadddcf33.md)
- A Study on the Immune Response and Safety of the Second Dose of an Investigational Chickenpox Vaccine When Given to Healthy Children 3 Months After a First Dose at 12 to 15 Months of Age
- A Study on the Safety of an Investigational Chickenpox Vaccine, When Given to Healthy Children, 12 to 15 Months of Age
- A Study to Evaluate Immunogenicity and Safety of GlaxoSmithKline (GSK)'s Infanrix Hexa Vaccine (DTPa-HBV-IPV/Hib) Versus MCM Vaccine BV's Vaxelis Vaccine (DTaP5-HBV-IPV-Hib) in Healthy Infants and Toddlers
- A Study to Learn About a Type of Pneumococcal Vaccine With a New Ingredient (PF-07872411) Intended to Enhance the Effects of the Vaccine Which is Given to Adults
- [A Study to Learn About How a New Pneumococcal Vaccine Works in Infants](https://trialight.com/data/trial/a-study-to-learn-about-how-a-new-pneumococcal-vaccine-works-fdff880f-c150-4e28-95c4-928e2be2f4e5.md)
- A Study to Learn How Effective is PCV20 to Help Stop Adults Who Have a Higher Chance of Getting Pneumonia
- A Study to Learn More About Prevenar 20 Once it is Out in the Korean Market
- An Alternative Booster Vaccine Against Meningitis and Ear Infections
- Assess Reacto- and Immunogenicity of Pneumococcal Conjugate Vaccine When Given as Booster or a 2 Dose Catch up Schedule
- Assessment of Novel Pneumococcal Conjugate Vaccination Scheduled in UK Infants
- [Clinical Trial of the 24-valent Pneumococcal Polysaccharide Conjugate Vaccine (CRM197/Tetanus Toxoid)](https://trialight.com/data/trial/clinical-trial-of-the-24-valent-pneumococcal-polysaccharide-aa125403-8a6c-418f-b3c1-206e6d85830b.md)
- Dose-Finding Study of S.Pneumoniae Whole Cell Vaccine Adsorbed to Alum (PATH-wSP) in Healthy Kenyan Adults and Toddlers
- Immunity to Serotype 19A Streptococcus Pneumoniae in Children Vaccinated With PCV10
- Immunogenicity and Safety of a Quadrivalent Meningococcal Conjugate Vaccine in Infants and Toddlers When Administered Concomitantly With Routine Pediatric Vaccines in the United Kingdom
- Immunogenicity and Safety of a Quadrivalent Meningococcal Conjugate Vaccine When Administered Concomitantly With Routine Pediatric Vaccines in Healthy Infants and Toddlers in the US
- Immunogenicity and Safety of a Tetanus-diphtheria Vaccine and a 13-valent Pneumococcal Conjugate Vaccine
- Immunogenicity and Safety of GlaxoSmithKline Biologicals' Infanrix™-IPV+Hib Vaccine

### Approved for (1)

- [Pneumococcal infection](https://trialight.com/data/condition/pneumococcal-infection-b3a7fc66-25ac-57f8-8fb4-073403fe8b1b.md)

### In development for (1)

- [Streptococcal infection](https://trialight.com/data/condition/streptococcal-infection-a0e9c8b4-cd46-573c-81e7-605778524e6c.md) Phase 3

---

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