> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/asset/sodium-iodide-ee931f47-7eee-4a51-bb78-8ffdc5f058b8
> Record changed: 2026-10-13

# Sodium iodide

Highest phase reached

Approved

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1644695)

Drug type

Small molecule

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1644695)

First approval year

1976

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1644695)

## Development status

**First approval year**

1976

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1644695)

**Listing at source**

Listed

**Highest phase reached**

Approved

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1644695)

## Names and chemistry

**Drug type**

Small molecule

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1644695)

**Drug name**

Sodium iodide

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1644695)

**Molecular weight**

149.89

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1644695)

**Structure (SMILES)**

These details could not be displayed.

### Other names (30)

- fdy 5301
- Fdy-5301
- FDY-5301
- Iodide
- Iodide (as sodium iodide)
- IODIDE (AS SODIUM IODIDE) \[VANDF\]
- iodide as sodium iodide
- iodide as sodium iodide vandf
- nsc 77388
- NSC-77388
- sodium iodide
- Sodium iodide
- SODIUM IODIDE \[EP MONOGRAPH\]
- SODIUM IODIDE \[HSDB\]
- SODIUM IODIDE \[II\]
- SODIUM IODIDE \[JAN\]
- SODIUM IODIDE \[MART.\]
- SODIUM IODIDE \[MI\]
- SODIUM IODIDE \[USP MONOGRAPH\]
- SODIUM IODIDE \[VANDF\]
- Sodium iodide \[WHO-DD\]
- sodium iodide ep monograph
- sodium iodide hsdb
- sodium iodide ii
- sodium iodide jan

And 5 more, listed on the interactive page.

## Identifiers

**CAS registry numbers**

- 7681-82-5

**ChEMBL ID**

CHEMBL1644695

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1644695)

**InChIKey**

FVAUCKIRQBBSSJ-UHFFFAOYSA-M

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1644695)

**PubChem compound IDs**

- 5238

**RxNorm IDs (RxCUI)**

- 9884

**FDA ingredient codes (UNII)**

- F5WR8N145C

## Regulatory information

### United States

**Applicant**

BRACCO

**Approval date**

2 May 1957

**Application number**

NDA010929

### Other regulatory facts

**First in class**

No

**Orphan designation**

No

**Availability**

Prescription only

## Pharmacology

### Drug classification

#### Administration routes

- Oral

### Investigated indications (2)

- **Condition**  
Myocardial Infarction

**Highest recorded phase**  
2

**Condition identifier**  
EFO:0008583

**Subject identifier**  
D009203
- **Condition**  
ST Elevation Myocardial Infarction

**Highest recorded phase**  
2

**Condition identifier**  
EFO:0008585

**Subject identifier**  
D000072657

### Open Targets indications (28)

- **Condition identifier**  
EFO\_0000612

**Highest recorded phase**  
2
- **Condition identifier**  
EFO\_0008583

**Highest recorded phase**  
3
- **Condition identifier**  
EFO\_0008585

**Highest recorded phase**  
3
- **Condition identifier**  
MONDO\_0002087

**Highest recorded phase**  
2
- **Condition identifier**  
MONDO\_0002120

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0004781

**Highest recorded phase**  
2
- **Condition identifier**  
MONDO\_0005005

**Highest recorded phase**  
2
- **Condition identifier**  
MONDO\_0005068

**Highest recorded phase**  
2
- **Condition identifier**  
MONDO\_0005086

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0005140

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0005203

**Highest recorded phase**  
2
- **Condition identifier**  
MONDO\_0005233

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0005575

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0006247

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0007254

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0008170

**Highest recorded phase**  
2
- **Condition identifier**  
MONDO\_0008233

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0009693

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0010150

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0011962

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0015486

**Highest recorded phase**  
3
- **Condition identifier**  
MONDO\_0015686

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0015759

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0015760

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0017827

**Highest recorded phase**  
1

And 3 more, listed on the interactive page.

### Reported adverse events (24)

- **Event**  
arthralgia

**Reports**  
3

**Reporting signal score**

9.67522
- **Event**  
asthenia

**Reports**  
2

**Reporting signal score**

11.2342
- **Event**  
condition aggravated

**Reports**  
1

**Reporting signal score**

10.9502
- **Event**  
contrast media allergy

**Reports**  
6

**Reporting signal score**

18.6416
- **Event**  
contrast media reaction

**Reports**  
4

**Reporting signal score**

8.65326
- **Event**  
dizziness

**Reports**  
3

**Reporting signal score**

14.5457
- **Event**  
drug hypersensitivity

**Reports**  
787

**Reporting signal score**  
2,862.27
- **Event**  
drug tolerance

**Reports**  
6

**Reporting signal score**

14.9971
- **Event**  
fatigue

**Reports**  
8

**Reporting signal score**

14.7408
- **Event**  
gastric bypass

**Reports**  
4

**Reporting signal score**

9.97167
- **Event**  
headache

**Reports**  
5

**Reporting signal score**

14.9295
- **Event**  
hyperleukocytosis

**Reports**  
6

**Reporting signal score**

21.2297
- **Event**  
injection site pain

**Reports**  
1

**Reporting signal score**

8.63422
- **Event**  
iodine allergy

**Reports**  
14

**Reporting signal score**

76.6343
- **Event**  
kidney perforation

**Reports**  
2

**Reporting signal score**

12.4737
- **Event**  
nausea

**Reports**  
17

**Reporting signal score**

8.01634
- **Event**  
placental insufficiency

**Reports**  
5

**Reporting signal score**

17.2313
- **Event**  
pneumonia

**Reports**  
1

**Reporting signal score**

11.8829
- **Event**  
polyhydramnios

**Reports**  
4

**Reporting signal score**

11.1323
- **Event**  
pyrexia

**Reports**  
3

**Reporting signal score**

11.5226
- **Event**  
renal aplasia

**Reports**  
4

**Reporting signal score**

13.7679
- **Event**  
symmetrical drug-related intertriginous and flexural exanthema

**Reports**  
3

**Reporting signal score**

9.26886
- **Event**  
urethral valves

**Reports**  
2

**Reporting signal score**

9.11648
- **Event**  
urinary ascites

**Reports**  
2

**Reporting signal score**

11.8373

### Trial references

- NCT03470441  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03470441)

## Chemical properties

**Prodrug**

No

**Chirality**

Achiral

**Inorganic**

Yes

**Heavy atoms**

2

**Molecular formula**

INa

**Monoisotopic mass**

149.89424

**Natural product**

No

## Evidence counts

**Recorded assays**

363

**Active assays**

2

### Active assay types

- Confirmatory

## Related records

### Trials (14)

- A Randomised Controlled Trial of Iodide Supplementation in Preterm Infants Follow-up at 2 Years
- A Study of Acute Myocardial Infarction Using FDY-5301
- Epithelium-On Corneal Cross-linking in Subjects 8 to 45 Years of Age With Keratoconus
- Epithelium-On Corneal Cross-linking in Subjects 8 to 45 Years of Age With Keratoconus
- [Evaluation in STEMI Patients Using FDY-5301](https://trialight.com/data/trial/evaluation-in-stemi-patients-using-fdy-5301-df498e24-db31-4737-acf3-6c9b79030629.md)
- Evaluation of FDY-5301 in Major Trauma Patients in ICU
- Intrapleural Measles Virus Therapy in Patients With Malignant Pleural Mesothelioma
- LISA-study : Levothyroxin in Nodular Goiter
- MV-NIS Infected Mesenchymal Stem Cells in Treating Recurrent Ovarian, Primary Peritoneal or Fallopian Tube Cancer
- MV-NIS or Investigator's Choice Chemotherapy in Treating Patients With Ovarian, Fallopian, or Peritoneal Cancer
- Recombinant Measles Virus Vaccine Therapy and Oncolytic Virus Therapy in Treating Patients With Progressive, Recurrent, or Refractory Ovarian Epithelial Cancer or Primary Peritoneal Cancer
- Vaccine Therapy in Treating Patients with Malignant Peripheral Nerve Sheath Tumor That is Recurrent or Cannot Be Removed by Surgery
- Vaccine Therapy With or Without Cyclophosphamide in Treating Patients With Recurrent or Refractory Multiple Myeloma
- Viral Therapy In Treating Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck Cancer or Metastatic Breast Cancer

### In development for (4)

- [Acute myocardial infarction](https://trialight.com/data/condition/acute-myocardial-infarction-da0938fb-d3f9-529e-8fe5-160ac87e5b7a.md) Phase 2
- Keratoconus Phase 3
- [Myocardial infarction](https://trialight.com/data/condition/myocardial-infarction-b4e97483-7435-5701-81dc-26d955e420ec.md) Phase 2
- [ST-elevation myocardial infarction](https://trialight.com/data/condition/st-elevation-myocardial-infarction-4462ec3a-15ca-527b-a581-39887b4bda63.md) Phase 2

---

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