> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/asset/selvacovatein-38412fcb-5455-41e7-a354-c86c8555de1d
> Record changed: 2026-10-13

# Selvacovatein

Highest phase reached

Approved

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL5314796)

Drug type

Protein

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL5314796)

First approval year

2023

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL5314796)

## Development status

**First approval year**

2023

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL5314796)

**Listing at source**

Listed

**Highest phase reached**

Approved

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL5314796)

## Names and chemistry

**Drug type**

Protein

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL5314796)

**Drug name**

Selvacovatein

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL5314796)

### Brand names (2)

- bimervax
- Bimervax

### Other names (8)

- bimervax
- BIMERVAX
- selvacovatein
- Selvacovatein
- selvacovateina
- Selvacovateina
- selvacovateine
- Selvacovateine

## Identifiers

**ChEMBL ID**

CHEMBL5314796

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL5314796)

## Regulatory information

### Other regulatory facts

**First in class**

No

**Orphan designation**

No

## Pharmacology

### Mechanisms of action

- **Mechanism**  
Spike glycoprotein vaccine antigen

**Action type**  
VACCINE\_ANTIGEN

**Target**  
Spike glycoprotein

**Protein identifier**  
P0DTC2

### Open Targets mechanisms

- **Mechanism**  
Spike glycoprotein vaccine antigen

**Action type**  
VACCINE ANTIGEN

**Target**  
Spike glycoprotein

### Investigated indications (2)

- **Condition**  
Vaccination

**Highest recorded phase**  
4

**Condition identifier**  
EFO:0004292

**Subject identifier**  
D014611
- **Condition**  
COVID-19

**Highest recorded phase**  
4

**Condition identifier**  
MONDO:0100096

**Subject identifier**  
D000086382

### Open Targets indications

- **Condition identifier**  
MONDO\_0100096

## Chemical properties

**Prodrug**

No

**Chirality**

Single enantiomer

**Inorganic**

No

**Natural product**

No

### Sequences (3)

- **Component**  
Glycosylation sites (N)

**Sequence**  
13 $ 25 $ 232 $ 244
- **Component**  
Sequence

**Type**  
Protein

**Sequence**  
RVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGNIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVKGFNCYFPLQSYGFQPTYGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKRVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTYGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNK
- **Component**  
Disulfide bridges

**Sequence**  
18-43 $ 61-114 $ 73-207 $ 162-70 $ 237-262 $ 280-333 $ 292-426 $ 381-389

## Related records

### Trials (2)

- [A Phase II Trial to Evaluate the Safety and Immunogenicity of BIMERVAX® When Coadministered With Seasonal Influenza Vaccine (SIIV) in Adults Older Than 65 Years of Age Fully Vaccinated Against COVID-19](https://trialight.com/data/trial/a-phase-ii-trial-to-evaluate-the-safety-and-immunogenicity-730d6e1b-3da0-47bb-a2dc-03b8c567e3bc.md)
- Open-label, Multi-centre, Non-Inferiority Study of Safety and Immunogenicity of BIMERVAX for the Prevention of COVID-19 in Adolescents From 12 Years to Less Than 18 Years of Age.

### Approved for (1)

- [COVID-19](https://trialight.com/data/condition/covid-19-13f0ebf3-c291-557d-bdef-93563d077103.md)

---

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