> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/asset/samrotecan-12957a7c-ea22-4660-b559-f9168fb36168
> Record changed: 2026-10-13

# Samrotecan

Highest phase reached

Phase 1

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068471)

Drug type

Small molecule

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068471)

## Development status

**Listing at source**

Listed

**Highest phase reached**

Phase 1

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068471)

## Names and chemistry

**Drug type**

Small molecule

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068471)

**Drug name**

Samrotecan

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068471)

**Structure (SMILES)**

O=c1n2c(-c3c(c4c5c(n3)ccc(NC(\[C@@H\](NC(\[C@@H\](NC(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN6C(=O)C=CC6=O)=O)=O)C(C)C)=O)C)=O)c5CCC4)C2)cc7c1COC(=O)\[C@@\]7(CC)O

Source: [gsrs.ncats.nih.gov](https://gsrs.ncats.nih.gov/ginas/app/beta/substances/J7299D2YCZ)

### Other names (12)

- az 14170133
- AZ-14170133
- az14170133
- AZ14170133
- samrotecan
- Samrotecan
- SAMROTECAN \[USAN\]
- samrotecan usan
- sg 3932
- SG-3932
- sg3932
- SG3932

## Identifiers

**CAS registry numbers**

- 2495742-34-0

**ChEMBL ID**

CHEMBL6068471

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068471)

**InChIKey**

OYYHJMUXFQIRBT-ZHSICCDKSA-N

Source: [gsrs.ncats.nih.gov](https://gsrs.ncats.nih.gov/ginas/app/beta/substances/J7299D2YCZ)

**PubChem compound IDs**

- 155142254

**FDA ingredient codes (UNII)**

- J7299D2YCZ

## Regulatory information

### Other regulatory facts

**First in class**

No

**Orphan designation**

No

## Pharmacology

### Drug classification

**Drug name stem**

\-tecan

### Investigated indications

- **Condition**  
Neoplasms

**Highest recorded phase**  
1

**Condition identifier**  
EFO:0000616

**Subject identifier**  
D009369

### Open Targets indications (2)

- **Condition identifier**  
EFO\_0000616
- **Condition identifier**  
MONDO\_0005070

## Chemical properties

**Calculated partition coefficient (XLogP)**

\-1.3

**Prodrug**

No

**Chirality**

Single enantiomer

**Inorganic**

No

**Heavy atoms**

82

**Monoisotopic mass**

1147.53250863

**Natural product**

No

## Related records

### Trials (1)

- [Phase I/IIa Study of AZD5335 as Monotherapy and Combination Therapy in Participants With Solid Tumors](https://trialight.com/data/trial/phase-i-iia-study-of-azd5335-as-monotherapy-and-combination-b67c0c74-ff64-4d06-9240-6e4caac374cf.md)

### In development for (1)

- Neoplasm Phase 1

---

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