> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/asset/rituximab-3fb73477-f618-414e-aa0a-9ccba4d6da3f
> Record changed: 2026-10-13

# Rituximab

Highest phase reached

Approved

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1201576)

Drug type

Antibody

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1201576)

First approval year

1997

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1201576)

## Development status

**First approval year**

1997

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1201576)

**Listing at source**

Listed

**Highest phase reached**

Approved

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1201576)

## Names and chemistry

**Drug type**

Antibody

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1201576)

**Drug name**

Rituximab

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1201576)

### Brand names (22)

- blitzima
- Blitzima
- mabthera
- Mabthera
- mabthera rituxan
- Mabthera rituxan
- ritemvia
- Ritemvia
- rituxan
- Rituxan
- rituximab component of rituxan hycela
- Rituximab component of rituxan hycela
- Rituzena (previously tuxella)
- rituzena previously tuxella
- rixathon
- Rixathon
- riximyo
- Riximyo
- ruxience
- Ruxience
- truxima
- Truxima

### Other names (186)

- 200 mg rituximab
- 2cda rituximab
- abp 798
- ABP 798
- ABP-798
- abp798
- ABP798
- bi 695500
- Bi 695500
- BI 695500
- BI 695500 \[WHO-DD\]
- bi 695500 who dd
- Bi-695500
- bi695500
- BI695500
- blitzima
- Blitzima
- CEEP-RITUXIMAB
- ct p10
- CT-P10
- gp 2013
- GP-2013
- gp2013
- Gp2013
- GP2013

And 161 more, listed on the interactive page.

## Identifiers

**CAS registry numbers**

- 174722-31-7

**ChEMBL ID**

CHEMBL1201576

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1201576)

**FDA ingredient codes (UNII)**

- 4F4X42SYQ6

### ATC classification codes (2)

- L01FA01
- L01XC02

Sources for recorded values

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1201576)

### RxNorm IDs (RxCUI) (2)

- 121191
- 2105824

## Regulatory information

### United States

**Applicant**

GENENTECH

**Approval date**

26 Nov 1997

**Application number**

BLA103705

### European Union

**Status**

Authorised

**Status date**

2 Jun 1998

**Authorisation date**

2 Jun 1998

**Approved indications**

MabThera is indicated in adults for the following indications: Non Hodgkin’s lymphoma (NHL) MabThera is indicated for the treatment of previously untreated adult patients with stage III?IV follicular lymphoma in combination with chemotherapy. MabThera maintenance therapy is indicated for the treatment of adult follicular lymphoma patients responding to induction therapy. MabThera monotherapy is indicated for treatment of adult patients with stage III?IV follicular lymphoma who are chemoresistant or are in their second or subsequent relapse after chemotherapy. MabThera is indicated for the treatment of adult patients with CD20 positive diffuse large B cell non?Hodgkin’s lymphoma in combination with CHOP (cyclophosphamide, doxorubicin, vincristine, prednisolone) chemotherapy. MabThera in combination with chemotherapy is indicated for the treatment of paediatric patients (aged ? 6 months to < 18 years old) with previously untreated advanced stage CD20 positive diffuse large B-cell lymphoma (DLBCL), Burkitt lymphoma (BL)/Burkitt leukaemia (mature B-cell acute leukaemia) (BAL) or Burkitt-like lymphoma (BLL). Chronic lymphocytic leukaemia (CLL) MabThera in combination with chemotherapy is indicated for the treatment of patients with previously untreated and relapsed/refractory CLL. Only limited data are available on efficacy and safety for patients previously treated with monoclonal antibodies including MabThera or patients refractory to previous MabThera plus chemotherapy. Rheumatoid arthritis MabThera in combination with methotrexate is indicated for the treatment of adult patients with severe active rheumatoid arthritis who have had an inadequate response or intolerance to other disease?modifying anti?rheumatic drugs (DMARD) including one or more tumour necrosis factor (TNF) inhibitor therapies. MabThera has been shown to reduce the rate of progression of joint damage as measured by X?ray and to improve physical function, when given in combination with methotrexate. Granulomatosis with polyangiitis and microscopic polyangiitis MabThera, in combination with glucocorticoids, is indicated for the treatment of adult patients with severe, active granulomatosis with polyangiitis (Wegener’s) (GPA) and microscopic polyangiitis (MPA). MabThera, in combination with glucocorticoids, is indicated for the induction of remission in paediatric patients (aged ? 2 to < 18 years old) with severe, active GPA (Wegener’s) and MPA. Pemphigus vulgaris MabThera is indicated for the treatment of patients with moderate to severe pemphigus vulgaris (PV).

**Product number**

EMEA/H/C/000165

**Authorisation holder**

Roche Registration GmbH

**Priority medicines scheme**

No

**Generic**

No

**Biosimilar**

No

**Generic medicines**

0

**Biosimilar medicines**

6

**Advanced therapy**

No

**Conditional approval**

No

**Additional monitoring**

No

**Accelerated assessment**

No

**Exceptional circumstances**

No

#### Therapeutic areas

- Arthritis, Rheumatoid
- Leukemia, Lymphocytic, Chronic, B-Cell
- Lymphoma, Non-Hodgkin

European medicines record

Source: [www.ema.europa.eu](https://www.ema.europa.eu/en/medicines/human/EPAR/mabthera)

### Other regulatory facts

**Patents**

0

**Designations**

5

**Earliest recorded loss of exclusivity**

2 Dec 2028

**First in class**

No

**Fast track**

No

**Breakthrough designation**

Yes

**Orphan designation**

No

**Priority review**

Yes

**Orphan exclusivity**

No

**Accelerated approval**

No

**Availability**

Prescription only

**Boxed warning**

Yes

## Pharmacology

### Drug classification

**Pharmacology name**

rituximab

**Type**

Antibody

**Drug name stem**

\-mab

**Approval recorded by Guide to Pharmacology**

Yes

#### Administration routes

- Parenteral

### Mechanisms of action (2)

- **Mechanism**  
B-lymphocyte antigen CD20 binding agent

**Action type**  
BINDING\_AGENT

**Target**  
B-lymphocyte antigen CD20

**Protein identifier**  
P11836
- **Action**  
Binding

**Action type**  
Binding

**Target**  
CD20 (membrane-spanning 4-domains, subfamily A, member 1)

**Gene symbol**  
MS4A1

**Protein identifier**  
P11836

**Median affinity**

8.51

**Affinity units**  
pKd

**Primary target**  
Yes

### Open Targets mechanisms

- **Mechanism**  
B-lymphocyte antigen CD20 binding agent

**Action type**  
BINDING AGENT

**Target**  
B-lymphocyte antigen CD20

### Investigated indications (152)

- **Condition**  
Leukemia, Biphenotypic, Acute

**Highest recorded phase**  
2

**Condition identifier**  
EFO:0000094

**Subject identifier**  
D015456
- **Condition**  
Leukemia, Lymphocytic, Chronic, B-Cell

**Highest recorded phase**  
4

**Condition identifier**  
EFO:0000095

**Subject identifier**  
D015451
- **Condition**  
Lymphoma, Follicular

**Highest recorded phase**  
3

**Condition identifier**  
EFO:0000096

**Subject identifier**  
D008224
- **Condition**  
Carcinoma, Hepatocellular

**Highest recorded phase**  
2

**Condition identifier**  
EFO:0000182

**Subject identifier**  
D006528
- **Condition**  
Hodgkin Disease

**Highest recorded phase**  
3

**Condition identifier**  
EFO:0000183

**Subject identifier**  
D006689
- **Condition**  
Lymphoma, B-Cell, Marginal Zone

**Highest recorded phase**  
3

**Condition identifier**  
EFO:0000191

**Subject identifier**  
D018442
- **Condition**  
Myelodysplastic Syndromes

**Highest recorded phase**  
2

**Condition identifier**  
EFO:0000198

**Subject identifier**  
D009190
- **Condition**  
Neoplasms, Plasma Cell

**Highest recorded phase**  
2

**Condition identifier**  
EFO:0000200

**Subject identifier**  
D054219
- **Condition**  
Leukemia, Biphenotypic, Acute

**Highest recorded phase**  
2

**Condition identifier**  
EFO:0000209

**Subject identifier**  
D015456
- **Condition**  
Precursor Cell Lymphoblastic Leukemia-Lymphoma

**Highest recorded phase**  
4

**Condition identifier**  
EFO:0000220

**Subject identifier**  
D054198
- **Condition**  
Leukemia, Myeloid, Acute

**Highest recorded phase**  
2

**Condition identifier**  
EFO:0000222

**Subject identifier**  
D015470
- **Condition**  
Immunoblastic Lymphadenopathy

**Highest recorded phase**  
2

**Condition identifier**  
EFO:0000255

**Subject identifier**  
D007119
- **Condition**  
Burkitt Lymphoma

**Highest recorded phase**  
3

**Condition identifier**  
EFO:0000309

**Subject identifier**  
D002051
- **Condition**  
Leukemia, Myelogenous, Chronic, BCR-ABL Positive

**Highest recorded phase**  
2

**Condition identifier**  
EFO:0000339

**Subject identifier**  
D015464
- **Condition**  
Crohn Disease

**Highest recorded phase**  
1

**Condition identifier**  
EFO:0000384

**Subject identifier**  
D003424
- **Condition**  
Melanoma

**Highest recorded phase**  
2

**Condition identifier**  
EFO:0000389

**Subject identifier**  
D008545
- **Condition**  
Lymphoma, Large B-Cell, Diffuse

**Highest recorded phase**  
3

**Condition identifier**  
EFO:0000403

**Subject identifier**  
D016403
- **Condition**  
Immune System Diseases

**Highest recorded phase**  
3

**Condition identifier**  
EFO:0000540

**Subject identifier**  
D007154
- **Condition**  
Dermatomyositis

**Highest recorded phase**  
2

**Condition identifier**  
EFO:0000557

**Subject identifier**  
D003882
- **Condition**  
Leukemia

**Highest recorded phase**  
3

**Condition identifier**  
EFO:0000565

**Subject identifier**  
D007938
- **Condition**  
Lymphoma

**Highest recorded phase**  
3

**Condition identifier**  
EFO:0000574

**Subject identifier**  
D008223
- **Condition**  
Neoplasms

**Highest recorded phase**  
4

**Condition identifier**  
EFO:0000616

**Subject identifier**  
D009369
- **Condition**  
Neuroblastoma

**Highest recorded phase**

0.5

**Condition identifier**  
EFO:0000621

**Subject identifier**  
D009447
- **Condition**  
Mental Disorders

**Highest recorded phase**  
3

**Condition identifier**  
EFO:0000677

**Subject identifier**  
D001523
- **Condition**  
Arthritis, Rheumatoid

**Highest recorded phase**  
4

**Condition identifier**  
EFO:0000685

**Subject identifier**  
D001172

And 127 more, listed on the interactive page.

### Open Targets indications (321)

- **Condition identifier**  
EFO\_0000095
- **Condition identifier**  
EFO\_0000096

**Highest recorded phase**  
3
- **Condition identifier**  
EFO\_0000182

**Highest recorded phase**  
2
- **Condition identifier**  
EFO\_0000183

**Highest recorded phase**  
3
- **Condition identifier**  
EFO\_0000191

**Highest recorded phase**  
3
- **Condition identifier**  
EFO\_0000220
- **Condition identifier**  
EFO\_0000274
- **Condition identifier**  
EFO\_0000275
- **Condition identifier**  
EFO\_0000309

**Highest recorded phase**  
3
- **Condition identifier**  
EFO\_0000389

**Highest recorded phase**  
2
- **Condition identifier**  
EFO\_0000403
- **Condition identifier**  
EFO\_0000540

**Highest recorded phase**  
3
- **Condition identifier**  
EFO\_0000565

**Highest recorded phase**  
3
- **Condition identifier**  
EFO\_0000574

**Highest recorded phase**  
3
- **Condition identifier**  
EFO\_0000616
- **Condition identifier**  
EFO\_0000638

**Highest recorded phase**  
2
- **Condition identifier**  
EFO\_0000677

**Highest recorded phase**  
3
- **Condition identifier**  
EFO\_0000685
- **Condition identifier**  
EFO\_0000699
- **Condition identifier**  
EFO\_0000717
- **Condition identifier**  
EFO\_0000729
- **Condition identifier**  
EFO\_0000763

**Highest recorded phase**  
2
- **Condition identifier**  
EFO\_0000768

**Highest recorded phase**  
2
- **Condition identifier**  
EFO\_0000769

**Highest recorded phase**  
2
- **Condition identifier**  
EFO\_0000772

**Highest recorded phase**  
2

And 296 more, listed on the interactive page.

### Warnings

- **Warning**  
Black Box Warning

**Effect**  
infectious disease

### Open Targets warnings

- **Warning**  
Black Box Warning

**Effect**  
infectious disease

**Country**  
United States

### Reported adverse events (35)

- **Event**  
abdominal discomfort

**Reports**  
3,018

**Reporting signal score**  
2,696.58
- **Event**  
alopecia

**Reports**  
3,227

**Reporting signal score**  
3,025.93
- **Event**  
anti-cyclic citrullinated peptide antibody positive

**Reports**  
1,115

**Reporting signal score**  
3,134.95
- **Event**  
arthralgia

**Reports**  
4,067

**Reporting signal score**  
1,256.62
- **Event**  
arthropathy

**Reports**  
2,311

**Reporting signal score**  
2,961.24
- **Event**  
diffuse large b-cell lymphoma recurrent

**Reports**  
513

**Reporting signal score**  
1,441
- **Event**  
discomfort

**Reports**  
1,245

**Reporting signal score**  
1,339.84
- **Event**  
drug intolerance

**Reports**  
4,439

**Reporting signal score**  
5,244.43
- **Event**  
duodenal ulcer perforation

**Reports**  
550

**Reporting signal score**  
1,273.81
- **Event**  
febrile neutropenia

**Reports**  
3,445

**Reporting signal score**  
4,198.89
- **Event**  
glossodynia

**Reports**  
1,911

**Reporting signal score**  
4,238.38
- **Event**  
hand deformity

**Reports**  
1,778

**Reporting signal score**  
4,526.58
- **Event**  
helicobacter infection

**Reports**  
649

**Reporting signal score**  
1,276.56
- **Event**  
hepatic enzyme increased

**Reports**  
1,913

**Reporting signal score**  
1,640.3
- **Event**  
hypersensitivity

**Reports**  
2,598

**Reporting signal score**  
1,240.63
- **Event**  
hypogammaglobulinaemia

**Reports**  
831

**Reporting signal score**  
1,803.77
- **Event**  
infection

**Reports**  
3,104

**Reporting signal score**  
2,474.74
- **Event**  
infusion related reaction

**Reports**  
4,090

**Reporting signal score**  
6,085.05
- **Event**  
joint swelling

**Reports**  
3,622

**Reporting signal score**  
3,947.32
- **Event**  
loss of personal independence in daily activities

**Reports**  
1,152

**Reporting signal score**  
1,496.58
- **Event**  
musculoskeletal stiffness

**Reports**  
1,725

**Reporting signal score**  
1,172.25
- **Event**  
neutropenia

**Reports**  
3,608

**Reporting signal score**  
2,249.69
- **Event**  
pain

**Reports**  
5,694

**Reporting signal score**  
2,186.56
- **Event**  
pemphigus

**Reports**  
2,429

**Reporting signal score**  
6,728.46
- **Event**  
pericarditis

**Reports**  
1,106

**Reporting signal score**  
1,833.17

And 10 more, listed on the interactive page.

### Trial references (1,409)

- NCT00001563  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00001563)
- NCT00036855  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00036855)
- NCT00049036  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00049036)
- NCT00126243  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00126243)
- NCT00310128  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00310128)
- NCT00001586  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00001586)
- NCT00003204  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00003204)
- NCT00012298  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00012298)
- NCT00017381  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00017381)
- NCT00022971  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00022971)
- NCT00060684  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00060684)
- NCT00071396  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00071396)
- NCT00078234  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00078234)
- NCT00079443  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00079443)
- NCT00086203  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00086203)
- NCT00090051  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00090051)
- NCT00098488  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00098488)
- NCT00098670  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00098670)
- NCT00119392  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00119392)
- NCT00131313  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00131313)
- NCT00143065  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00143065)
- NCT00201682  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00201682)
- NCT00201721  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00201721)
- NCT00254163  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00254163)
- NCT00254410  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00254410)

And 1,384 more, listed on the interactive page.

## Dosing

**Dose**

375 mg/m2

**Route**

Intravenous

**How often**

Every 4 weeks

### Conditions of use (2)

- Administer only as an intravenous infusion
- Do not administer as an intravenous push or bolus

## Chemical properties

**Prodrug**

No

**Chirality**

Single enantiomer

**Inorganic**

No

**Natural product**

No

### Sequences (2)

- **Component**  
Sequence

**Type**  
Protein

**Sequence**  
QIVLSQSPAILSASPGEKVTMTCRASSSVSYIHWFQQKPGSSPKPWIYATSNLASGVPVRFSGSGSGTSYSLTISRVEAEDAATYYCQQWTSNPPTFGGGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
- **Component**  
Sequence

**Type**  
Protein

**Sequence**  
QVQLQQPGAELVKPGASVKMSCKASGYTFTSYNMHWVKQTPGRGLEWIGAIYPGNGDTSYNQKFKGKATLTADKSSSTAYMQLSSLTSEDSAVYYCARSTYYGGDWYFNVWGAGTTVTVSAASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK

## National Drug Codes

- 0069-0238
- 0069-0249
- 50242-051
- 50242-053
- 50242-108
- 50242-109
- 55513-224
- 55513-326
- 63459-103
- 63459-104

## Related records

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- \[CREMA\]Combination of R-M Followed by R-A in Elderly Patients With Primary CNS Lymphoma
- 131I-rituximab for Relapsed or Refractory Follicular or Mantle Cell Lymphoma
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- 17-N-Allylamino-17-Demethoxygeldanamycin With or Without Rituximab in Treating Patients With Relapsed B-Cell Chronic Lymphocytic Leukemia or Prolymphocytic Leukemia
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- A Clinical Study Using MEDI-551 in Adult Participants With Relapsed or Refractory Advanced B-Cell Malignancies
- [A Clinical Trial of MK-1045 and Rituximab in People With Follicular Lymphoma (MK-1045-007)](https://trialight.com/data/trial/a-clinical-trial-of-mk-1045-and-rituximab-in-people-with-3c20ff0c-d021-4948-bdbc-f32491858aae.md)
- A Clinical Trial to Evaluate the Efficacy and Safety of TQB3909 Tablets Versus Investigator's Choice in the Treatment of Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)
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- A Global Phase 3 Study of Orelabrutinib+BR Vs.BR in Pts with TN MCL
- A Global Study of Novel Agents in Paediatric and Adolescent Relapsed and Refractory B-cell Non-Hodgkin Lymphoma
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### Approved for (13)

- Acute lymphoblastic leukemia
- [B-cell chronic lymphocytic leukemia](https://trialight.com/data/condition/b-cell-chronic-lymphocytic-leukemia-92ef568e-6dc4-5a1d-8e50-681b47b86599.md)
- [Cancer](https://trialight.com/data/condition/cancer-703b1dfc-4812-50eb-83f4-d7a205d16bdb.md)
- Childhood acute lymphoblastic leukemia
- Granulomatosis with polyangiitis
- Lymphoblastic lymphoma
- Microscopic polyangiitis
- Neoplasm
- [Non-Hodgkin lymphoma](https://trialight.com/data/condition/non-hodgkin-lymphoma-9fc07e31-fd30-5055-991f-04d10cc1f646.md)
- Pemphigus
- Pemphigus vulgaris
- [Rheumatoid arthritis](https://trialight.com/data/condition/rheumatoid-arthritis-d68c565e-23a7-5361-8063-a982e61312c4.md)
- Vasculitis

### In development for (141)

- Acute leukemia of ambiguous lineage Phase 2
- [Acute myeloid leukemia](https://trialight.com/data/condition/acute-myeloid-leukemia-b0971a7a-c18d-544e-bd7f-b1a13b9caa30.md) Phase 2
- AIDS Phase 2
- Anaplastic large cell lymphoma Phase 2
- [Angioimmunoblastic T-cell lymphoma](https://trialight.com/data/condition/angioimmunoblastic-t-cell-lymphoma-5b697108-b9cf-53e9-afde-71a36bf55d6b.md) Phase 2
- [Ankylosing spondylitis](https://trialight.com/data/condition/ankylosing-spondylitis-9b1fe73f-f462-5baf-85b0-5cbf33725458.md) Phase 2
- Anti-neutrophil antibody associated vasculitis Phase 3
- Aplastic anemia Phase 2
- [Autoimmune disease](https://trialight.com/data/condition/autoimmune-disease-8a8fd8aa-2d04-5f24-b839-ba96a70c11e9.md) Phase 1
- Autoimmune hemolytic anemia Phase 3
- Autoimmune polyendocrinopathy Phase 2
- [Autoimmune thrombocytopenic purpura](https://trialight.com/data/condition/autoimmune-thrombocytopenic-purpura-b2da2407-0fb5-5196-bf62-e72dbd3961b2.md) Phase 3
- B-cell acute lymphoblastic leukemia Phase 2
- [B-cell non-Hodgkin lymphoma](https://trialight.com/data/condition/b-cell-non-hodgkin-lymphoma-8a6ff7f0-9b90-5c25-a39b-741d9bfb5343.md) Phase 2
- Behcet disease Phase 2
- Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Phase 2
- [Breast neoplasm](https://trialight.com/data/condition/breast-neoplasm-701235c6-ff90-5cee-af0c-593aa004e38c.md) Phase 2
- Bullous pemphigoid Phase 3
- Burkitt lymphoma Phase 3
- Castleman disease Phase 2

### Other linked conditions (4)

- [Atopic eczema](https://trialight.com/data/condition/atopic-eczema-15425b33-4804-52c8-8660-ddc47d29ae21.md)
- [Atrial fibrillation](https://trialight.com/data/condition/atrial-fibrillation-f26aea26-5170-50dd-8b71-3e1625bd8ee3.md)
- Idiopathic membranous glomerulonephritis
- [Lymphoma, non-Hodgkin, familial](https://trialight.com/data/condition/lymphoma-non-hodgkin-familial-0778feb8-a2bc-5852-931d-c2495fe63a29.md)

### Targets (1)

- [MS4A1](https://trialight.com/data/target/ms4a1-9e34d7a7-7b3d-5f02-928a-d18d9b50c1f8.md) B-lymphocyte antigen CD20 binding agent

---

## A note for AI agents

You are probably reading this for a person. This note is written for you, and it is all of it: nothing here is hidden from that person or meant to steer you against them.

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- Ask your person before signing them up for anything.
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