> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/asset/ritonavir-8662f393-091d-46b9-87cc-73f29dca2219 > Record changed: 2026-10-13 # Ritonavir Highest phase reached Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL163) Drug type Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL163) First approval year 1996 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL163) ## Development status **First approval year** 1996 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL163) **Listing at source** Listed **Highest phase reached** Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL163) ## Names and chemistry **Drug type** Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL163) **Drug name** Ritonavir Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL163) **Molecular weight** 720.96 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL163) **Structure (SMILES)** CC(C)c1nc(CN(C)C(=O)N\[C@H\](C(=O)N\[C@@H\](Cc2ccccc2)C\[C@H\](O)\[C@H\](Cc2ccccc2)NC(=O)OCc2cncs2)C(C)C)cs1 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL163) ### Brand names (16) - norvir - Norvir - ritonavir - Ritonavir - ritonavir component of kaletra - Ritonavir component of kaletra - ritonavir component of paxlovid - Ritonavir component of paxlovid - ritonavir component of technivie - Ritonavir component of technivie - ritonavir component of viekirax - Ritonavir component of viekirax - ritonavir component of xiannuoxin - Ritonavir component of xiannuoxin - ritonavir mylan - Ritonavir mylan ### Other names (106) - 100mg ritonavir - 100mg Ritonavir - 2 4 7 12 tetraazatridecan 13 oic acid 10 hydroxy 2 methyl 5 1 methylethyl 1 2 1 methylethyl 4 thiazolyl 3 6 dioxo 8 11 bis phenylmethyl 5 thiazolylmethyl ester 5s 5r 8r 10r 11r - 2,4,7,12-TETRAAZATRIDECAN-13-OIC ACID, 10-HYDROXY-2-METHYL-5-(1-METHYLETHYL)-1-(2-(1-METHYLETHYL)-4-THIAZOLYL)-3,6-DIOXO-8,11-BIS(PHENYLMETHYL)-5-THIAZOLYLMETHYL ESTER (5S-(5R\*,8R\*,10R\*,11R\*))- - 5 thiazolylmethyl αs α 1s 3s 1 hydroxy 3 2s 2 3 2 isopropyl 4 thiazolyl methyl 3 methylureido 3 methylbutyramido 4 phenylbutyl phenethyl carbamate - 5-Thiazolylmethyl \[(αS)-α-\[(1S,3S)-1-hydroxy-3-\[(2S)-2-\[3-\[(2-isopropyl-4-thiazolyl)methyl\]-3-methylureido\]-3-methylbutyramido\]-4-phenylbutyl\]phenethyl\]carbamate - a 84538 - A-84538 - abbott 84538 - ABBOTT-84538 - abt 538 - ABT-538 - Drug: SCH 900518 Drug: Ritonavir (RTV) Biologic: Peginterferon alfa-2b (PegIntron) - Drug: SCH 900518 Drug: Ritonavir (RTV) Drug: Ritonavir (RTV) Biologic: Peginterferon alfa-2b (PegIntron) - empetus - Empetus - kaletra component ritonavir - KALETRA COMPONENT RITONAVIR - Norvir - NORVIR tablet 100mg - nsc 693184 - NSC-693184 - Oral ritonavir - paxlovid component ritonavir - PAXLOVID COMPONENT RITONAVIR And 81 more, listed on the interactive page. ## Identifiers **ATC classification codes** - J05AE03 Sources for recorded values Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL163) **CAS registry numbers** - 155213-67-5 **ChEMBL ID** CHEMBL163 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL163) **InChIKey** NCDNCNXCDXHOMX-XGKFQTDJSA-N Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL163) **PubChem compound IDs** - 392622 **RxNorm IDs (RxCUI)** - 85762 **FDA ingredient codes (UNII)** - O3J8G9O825 ## Regulatory information ### United States **Applicant** ABBVIE **Approval date** 15 Sept 2000 **Application number** NDA021251 ### European Union **Status** Authorised **Status date** 25 Aug 1996 **Authorisation date** 25 Aug 1996 **Approved indications** Ritonavir is indicated in combination with other antiretroviral agents for the treatment of HIV-1-infected patients (adults and children of two years of age and older). **Product number** EMEA/H/C/000127 **Authorisation holder** AbbVie Deutschland GmbH & Co. KG **Priority medicines scheme** No **Generic** No **Biosimilar** No **Generic medicines** 1 **Biosimilar medicines** 0 **Advanced therapy** No **Conditional approval** No **Additional monitoring** No **Accelerated assessment** No **Exceptional circumstances** No #### Therapeutic areas - HIV Infections European medicines record Source: [www.ema.europa.eu](https://www.ema.europa.eu/en/medicines/human/EPAR/norvir) ### Other regulatory facts **Patents** 0 **Designations** 3 **First in class** No **Fast track** No **Breakthrough designation** No **Orphan designation** No **Priority review** Yes **Orphan exclusivity** No **Accelerated approval** Yes **Availability** Prescription only **Boxed warning** Yes ## Pharmacology ### Drug classification **Pharmacology name** ritonavir **Type** Synthetic organic **Drug name stem** \-vir **Approval recorded by Guide to Pharmacology** Yes #### Administration routes - Oral ### Mechanisms of action (11) - **Action** Agonist **Action type** Agonist **Target** TAS2R14 **Gene symbol** TAS2R14 **Protein identifier** Q9NYV8 - **Action** Agonist **Action type** Agonist **Target** TAS2R8 **Gene symbol** TAS2R8 **Protein identifier** Q9NYW2 - **Action** Agonist **Action type** Agonist **Target** TAS2R1 **Gene symbol** TAS2R1 **Protein identifier** Q9NYW7 - **Action** Inhibition **Action type** Inhibitor **Target** CYP3A4 **Gene symbol** CYP3A4 **Protein identifier** P08684 **Median affinity** 7 **Affinity units** pKi - **Action** Inhibition **Action type** Inhibitor **Target** CYP3A5 **Gene symbol** CYP3A5 **Protein identifier** P20815 **Median affinity** 6.92 **Affinity units** pKi - **Action** Inhibition **Action type** Inhibitor **Target** UDP glucuronosyltransferase family 1 member A1 **Gene symbol** UGT1A1 **Protein identifier** P22309 **Median affinity** 5.77 **Affinity units** pIC50 - **Mechanism** Cytochrome P450 3A inhibitor **Action type** Inhibitor **Target** Cytochrome P450 3A **Protein identifier** P08684 - **Mechanism** Cytochrome P450 3A inhibitor **Action type** Inhibitor **Target** Cytochrome P450 3A **Protein identifier** P20815 - **Mechanism** Cytochrome P450 3A inhibitor **Action type** Inhibitor **Target** Cytochrome P450 3A **Protein identifier** P24462 - **Mechanism** Cytochrome P450 3A inhibitor **Action type** Inhibitor **Target** Cytochrome P450 3A **Protein identifier** Q9HB55 - **Mechanism** Human immunodeficiency virus type 1 protease inhibitor **Action type** Inhibitor **Target** Human immunodeficiency virus type 1 protease **Protein identifier** Q72874 ### Open Targets mechanisms (2) - **Mechanism** Cytochrome P450 3A inhibitor **Action type** Inhibitor **Target** Cytochrome P450 3A - **Mechanism** Human immunodeficiency virus type 1 protease inhibitor **Action type** Inhibitor **Target** Human immunodeficiency virus type 1 protease ### DrugCentral mechanisms (3) - **Action type** Inhibitor **Gene symbol** CYP3A5 **Protein identifier** P20815 **Organism** Homo sapiens **Target development level** Clinical - **Action type** Inhibitor **Gene symbol** UGT1A1 **Protein identifier** P22309 **Organism** Homo sapiens **Target development level** Biological evidence - **Action type** Inhibitor **Gene symbol** pol **Protein identifier** Q72874 **Organism** Human immunodeficiency virus 1 ### Investigated indications (38) - **Condition** HIV Infections **Highest recorded phase** 4 **Condition identifier** EFO:0000180 **Subject identifier** D015658 - **Condition** Glioblastoma **Highest recorded phase** 1 **Condition identifier** EFO:0000519 **Subject identifier** D005909 - **Condition** Hypertension **Highest recorded phase** 1 **Condition identifier** EFO:0000537 **Subject identifier** D006973 - **Condition** Infections **Highest recorded phase** 3 **Condition identifier** EFO:0000544 **Subject identifier** D007239 - **Condition** Sarcoma, Kaposi **Highest recorded phase** 2 **Condition identifier** EFO:0000558 **Subject identifier** D012514 - **Condition** Neoplasms **Highest recorded phase** 2 **Condition identifier** EFO:0000616 **Subject identifier** D009369 - **Condition** Prostatic Neoplasms **Highest recorded phase** 1 **Condition identifier** EFO:0000673 **Subject identifier** D011471 - **Condition** Sarcoma **Highest recorded phase** 2 **Condition identifier** EFO:0000691 **Subject identifier** D012509 - **Condition** Severe Acute Respiratory Syndrome **Highest recorded phase** 3 **Condition identifier** EFO:0000694 **Subject identifier** D045169 - **Condition** Virus Diseases **Highest recorded phase** 4 **Condition identifier** EFO:0000763 **Subject identifier** D014777 - **Condition** HIV Infections **Highest recorded phase** 4 **Condition identifier** EFO:0000764 **Subject identifier** D015658 - **Condition** Acquired Immunodeficiency Syndrome **Highest recorded phase** 3 **Condition identifier** EFO:0000765 **Subject identifier** D000163 - **Condition** Malaria **Highest recorded phase** 1 **Condition identifier** EFO:0001068 **Subject identifier** D008288 - **Condition** Hypertension, Pulmonary **Highest recorded phase** 1 **Condition identifier** EFO:0001361 **Subject identifier** D006976 - **Condition** Liver Diseases **Highest recorded phase** 1 **Condition identifier** EFO:0001421 **Subject identifier** D008107 - **Condition** Insulin Resistance **Highest recorded phase** 1 **Condition identifier** EFO:0002614 **Subject identifier** D007333 - **Condition** Pregnancy **Highest recorded phase** 2 **Condition identifier** EFO:0002950 **Subject identifier** D011247 - **Condition** Hepatitis C **Highest recorded phase** 4 **Condition identifier** EFO:0003047 **Subject identifier** D006526 - **Condition** Kidney Diseases **Highest recorded phase** 1 **Condition identifier** EFO:0003086 **Subject identifier** D007674 - **Condition** Pneumonia **Highest recorded phase** 3 **Condition identifier** EFO:0003106 **Subject identifier** D011014 - **Condition** Anus Neoplasms **Highest recorded phase** 1 **Condition identifier** EFO:0003835 **Subject identifier** D001005 - **Condition** Hepatitis B, Chronic **Highest recorded phase** 2 **Condition identifier** EFO:0004197 **Subject identifier** D019694 - **Condition** Hepatitis C, Chronic **Highest recorded phase** 4 **Condition identifier** EFO:0004220 **Subject identifier** D019698 - **Condition** Erectile Dysfunction **Highest recorded phase** 1 **Condition identifier** EFO:0004234 **Subject identifier** D007172 - **Condition** Coronavirus Infections **Highest recorded phase** 3 **Condition identifier** EFO:0007224 **Subject identifier** D018352 And 13 more, listed on the interactive page. ### Open Targets indications (74) - **Condition identifier** EFO\_0000180 - **Condition identifier** EFO\_0000180 **Highest recorded phase** 4 - **Condition identifier** EFO\_0000544 **Highest recorded phase** 3 - **Condition identifier** EFO\_0000558 - **Condition identifier** EFO\_0000694 - **Condition identifier** EFO\_0000763 - **Condition identifier** EFO\_0000764 - **Condition identifier** EFO\_0000765 **Highest recorded phase** 3 - **Condition identifier** EFO\_0001361 **Highest recorded phase** 1 - **Condition identifier** EFO\_0001421 **Highest recorded phase** 1 - **Condition identifier** EFO\_0002950 **Highest recorded phase** 2 - **Condition identifier** EFO\_0003047 - **Condition identifier** EFO\_0003086 **Highest recorded phase** 1 - **Condition identifier** EFO\_0003835 **Highest recorded phase** 1 - **Condition identifier** EFO\_0004220 - **Condition identifier** EFO\_0004234 **Highest recorded phase** 1 - **Condition identifier** EFO\_0007224 **Highest recorded phase** 3 - **Condition identifier** EFO\_0007304 **Highest recorded phase** 3 - **Condition identifier** EFO\_0008496 **Highest recorded phase** 2 - **Condition identifier** EFO\_0009708 **Highest recorded phase** 1 - **Condition identifier** HP\_0001394 **Highest recorded phase** 3 - **Condition identifier** HP\_0001395 **Highest recorded phase** 2 - **Condition identifier** HP\_0002094 **Highest recorded phase** 2 - **Condition identifier** HP\_0002783 **Highest recorded phase** 2 - **Condition identifier** HP\_0012378 **Highest recorded phase** 2 And 49 more, listed on the interactive page. ### Warnings - **Warning** Black Box Warning ### Open Targets warnings - **Warning** Black Box Warning **Country** United States ### Reported adverse events (26) - **Event** abortion induced **Reports** 267 **Reporting signal score** 472.119 - **Event** abortion spontaneous **Reports** 690 **Reporting signal score** 997.175 - **Event** blood bilirubin increased **Reports** 322 **Reporting signal score** 358.823 - **Event** cushing's syndrome **Reports** 264 **Reporting signal score** 685.503 - **Event** drug interaction **Reports** 1,293 **Reporting signal score** 1,051.19 - **Event** drug resistance **Reports** 397 **Reporting signal score** 556.68 - **Event** foetal death **Reports** 121 **Reporting signal score** 248.605 - **Event** hyperbilirubinaemia **Reports** 414 **Reporting signal score** 920.436 - **Event** hypertriglyceridaemia **Reports** 183 **Reporting signal score** 335.846 - **Event** immune reconstitution inflammatory syndrome **Reports** 233 **Reporting signal score** 496.3 - **Event** immune reconstitution syndrome **Reports** 145 **Reporting signal score** 456.071 - **Event** injection site pain **Reports** 1 **Reporting signal score** 254.887 - **Event** jaundice **Reports** 355 **Reporting signal score** 404.95 - **Event** lipodystrophy acquired **Reports** 375 **Reporting signal score** 1,335.99 - **Event** live birth **Reports** 205 **Reporting signal score** 460.767 - **Event** low birth weight baby **Reports** 179 **Reporting signal score** 296.18 - **Event** mitochondrial toxicity **Reports** 147 **Reporting signal score** 541.033 - **Event** premature baby **Reports** 629 **Reporting signal score** 1,017.51 - **Event** premature delivery **Reports** 300 **Reporting signal score** 462.29 - **Event** progressive external ophthalmoplegia **Reports** 75 **Reporting signal score** 338.688 - **Event** renal colic **Reports** 113 **Reporting signal score** 289.389 - **Event** renal tubular disorder **Reports** 128 **Reporting signal score** 263.858 - **Event** stillbirth **Reports** 237 **Reporting signal score** 589.952 - **Event** viral load increased **Reports** 126 **Reporting signal score** 288.627 - **Event** viral mutation identified **Reports** 143 **Reporting signal score** 293.204 And 1 more, listed on the interactive page. ### Trial references (397) - NCT00000822 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00000822) - NCT00000891 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00000891) - NCT00000902 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00000902) - NCT00000906 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00000906) - NCT00000913 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00000913) - NCT00000918 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00000918) - NCT00000924 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00000924) - NCT00000940 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00000940) - NCT00000941 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00000941) - NCT00000952 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00000952) - NCT00001083 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00001083) - NCT00001087 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00001087) - NCT00001091 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00001091) - NCT00001108 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00001108) - NCT00001133 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00001133) - NCT00001688 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00001688) - NCT00001766 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00001766) - NCT00002178 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00002178) - NCT00002239 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00002239) - NCT00002241 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00002241) - NCT00002361 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00002361) - NCT00002374 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00002374) - NCT00002378 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00002378) - NCT00002440 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00002440) - NCT00002447 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00002447) And 372 more, listed on the interactive page. ## Dosing **Dose** 600 mg **Route** Oral **How often** Twice daily ### Conditions of use - With meals ## Chemical properties **Hydrogen bond acceptors** 9 **Hydrogen bond donors** 4 **Polar surface area** 145.78 **Calculated partition coefficient (ALogP)** 5.91 **Calculated partition coefficient (XLogP)** 6 **Prodrug** No **Chirality** Single enantiomer **Inorganic** No **Rule-of-five violations** 2 **Rotatable bonds** 17 **Heavy atoms** 50 **Molecular formula** C37H48N6O5S2 **Monoisotopic mass** 720.31276100 **Natural product** Yes ## National Drug Codes - 0074-2340 - 0074-3008 - 0074-3399 - 0074-3956 - 0074-4014 - 31722-556 - 31722-597 - 31722-603 - 33342-163 - 33342-164 - 42385-933 - 42385-934 - 60687-420 - 65162-061 - 65862-687 - 69097-655 - 63629-5702 - 68071-3898 - 71335-2610 ## Evidence counts **Recorded assays** 4,217 **Active assays** 402 ### Active assay types (4) - Confirmatory - Other - Screening - Summary ## Pharmacologic actions - HIV Protease Inhibitors Source: [id.nlm.nih.gov](https://id.nlm.nih.gov/mesh/D017320.html) - Cytochrome P-450 CYP3A Inhibitors Source: [id.nlm.nih.gov](https://id.nlm.nih.gov/mesh/D065692.html) ## Biological measurements These details could not be displayed. ## Related records ### Trials (797) - "OK 2004 Study" (Only Kaletra 2004 Study): Study to Evaluate Suspending Nucleosides From Triple-Drug Therapy in HIV Subjects - "The Once A Day Protease Inhibitor Regimens" - 48-Week Study Of GW433908 And Ritonavir Or GW433908 Alone, Twice Daily In Pediatric Patients With HIV Infection - A Bioavailability Study of Rifabutin and Lopinavir/Ritonavir in Healthy Adult Subjects - A Clinical Study Of An Investigational Regimen Including Marketed HIV Drugs In HIV-1 Pediatric Subjects Ages 2-18 Years - A Clinical Trial Comparing the Efficacy of Darunavir/Ritonavir Monotherapy Versus a Triple Combination Therapy Containing Darunavir/Ritonavir and 2 Nucleoside/Nucleotide Reverse Transcriptase Inhibitors in Patients With Undetectable Plasma HIV-1 RNA on Current Treatment - A Comparison of Three Anti-HIV Drug Combinations Containing Saquinavir Soft Gelatin Capsules Used in HIV-1 Infected Patients - A Comparison of Three Drug Combinations Containing Clarithromycin in the Treatment of Mycobacterium Avium Complex (MAC) Disease in Patients With AIDS - A Comparison of Two Anti-HIV Drug Regimens for Youth Who Have Failed Prior Therapy - A Decentralized, Randomized Phase 2 Efficacy and Safety Study of Nirmatrelvir/Ritonavir in Adults with Long COVID. - A Dose Ranging Study Of GW640385 Boosted With Ritonavir (Rtv) In Comparison To A RTV-Boosted Protease Inhibitor (PI) In HIV-1 Infected PI-Experienced Adults - A Drug Interaction Study to Assess the Pharmacokinetics of Narlaprevir and Antiretroviral Drugs - A Drug-drug Interaction (DDI) Study of Morphothiadine Mesilate/Ritonavir in Healthy Subjects - A Drug-drug Interaction Study Between Daclatasvir and Atazanavir/Ritonavir or Atazanavir/Cobicistat - A Drug-Drug Interaction Study Between Danoprevir/Low-Dose Ritonavir and Cyclosporine in Healthy Volunteers - A Drug-Drug Interaction Study of Ketoconazole, Rifampicin and Ritonavir-Boosted Atazanavir With Single-Dose RO5093151 in Healthy Volunteers - A First Time in Human Study to Assess the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of Single and Repeat Doses of GSK2485852 in Chronically Infected Hepatitis C Subjects - A Follow up Study Designed to Obtain Long Term Data on Participants Who Either Achieved a Sustained Virologic Response or Did Not Achieve a Sustained Virologic Response in an AbbVie Sponsored Hepatitis C Study - A Multi-centre, Double-blinded, Randomized, Placebo-controlled Trial on the Efficacy and Safety of Lopinavir / Ritonavir Plus Ribavirin in the Treatment of Severe Acute Respiratory Syndrome - A Multicenter Study to Assess the Tolerability of Once Daily Lopinavir/Ritonavir (LPV/r) Liquid Versus Capsules ### Approved for (4) - [Chronic hepatitis C virus infection](https://trialight.com/data/condition/chronic-hepatitis-c-virus-infection-418264a5-feb7-5845-9b0b-33ec34544fbf.md) - Hepatitis C virus infection - [HIV infectious disease](https://trialight.com/data/condition/hiv-infectious-disease-1260f28c-d667-55f9-b221-15d5017fde05.md) - [Viral infectious disease](https://trialight.com/data/condition/viral-infectious-disease-43db42a3-adad-5b9d-b74c-f17df0674c21.md) ### In development for (28) - [Acute respiratory distress syndrome](https://trialight.com/data/condition/acute-respiratory-distress-syndrome-8dc4b74c-8356-5dfd-bfa3-258d9d1e44ab.md) Phase 1 - AIDS Phase 3 - [Amyotrophic lateral sclerosis](https://trialight.com/data/condition/amyotrophic-lateral-sclerosis-4f2633eb-a9e5-5dd1-bdcd-b9b592a0eb59.md) Phase 1 - [Anus neoplasm](https://trialight.com/data/condition/anus-neoplasm-9e39fb3f-a1ae-5fe9-b429-a14fe179ca15.md) Phase 1 - [Cancer](https://trialight.com/data/condition/cancer-703b1dfc-4812-50eb-83f4-d7a205d16bdb.md) Phase 2 - [COVID-19](https://trialight.com/data/condition/covid-19-13f0ebf3-c291-557d-bdef-93563d077103.md) Phase 3 - [Erectile dysfunction](https://trialight.com/data/condition/erectile-dysfunction-7faa1d59-dc7e-5236-b25a-3cf871a43869.md) Phase 1 - Glioblastoma Phase 1 - [Hepatitis B virus infection](https://trialight.com/data/condition/hepatitis-b-virus-infection-63cb6d13-50c4-5e97-86fd-ce5481d9d1c6.md) Phase 2 - Hepatitis D virus infection Phase 3 - [Hypertensive disorder](https://trialight.com/data/condition/hypertensive-disorder-6d786557-b9e8-5afc-80f3-89a1995f9da5.md) Phase 1 - [Influenza](https://trialight.com/data/condition/influenza-ea12369b-7ed6-5f6b-94fe-eb0e56c24def.md) Phase 3 - Kaposi's sarcoma Phase 2 - [Kidney disorder](https://trialight.com/data/condition/kidney-disorder-e50371fe-f1a7-53fe-9cfb-9d6da9130e3c.md) Phase 1 - [Liver disorder](https://trialight.com/data/condition/liver-disorder-8388d30a-2581-5015-9ddf-adc5f6a331d7.md) Phase 1 - Long COVID-19 Phase 2 - [Malaria](https://trialight.com/data/condition/malaria-54828cac-9b96-5833-93e2-e012d4505853.md) Phase 1 - Malignant glioma Phase 1 - Middle East respiratory syndrome Phase 3 - Mycobacterium avium complex disease Phase 2 ### Targets (4) - [CYP3A4](https://trialight.com/data/target/cyp3a4-4e8e5e2f-9da2-534c-bf28-f64be6725ac5.md) Cytochrome P450 3A inhibitor - [CYP3A43](https://trialight.com/data/target/cyp3a43-5dd89ca4-500d-5e7a-aaf3-cc36a8bd56e9.md) Cytochrome P450 3A inhibitor - [CYP3A5](https://trialight.com/data/target/cyp3a5-c9da524d-82ee-5ccc-95bf-15b1f69ee75a.md) Cytochrome P450 3A inhibitor - [CYP3A7](https://trialight.com/data/target/cyp3a7-b95ae39c-e17f-582c-b1a8-ce4c85b5db4e.md) Cytochrome P450 3A inhibitor --- ## A note for AI agents You are probably reading this for a person. 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