> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/asset/rimiducid-79fac8a6-a578-4bca-8782-486be86945d8
> Record changed: 2026-10-13

# Rimiducid

Highest phase reached

Phase 2

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL269259)

Drug type

Small molecule

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL269259)

## Development status

**Listing at source**

Listed

**Highest phase reached**

Phase 2

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL269259)

## Names and chemistry

**Drug type**

Small molecule

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL269259)

**Drug name**

Rimiducid

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL269259)

**Molecular weight**

1,411.65

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL269259)

**Structure (SMILES)**

CC\[C@H\](C(=O)N1CCCC\[C@H\]1C(=O)O\[C@H\](CCc1ccc(OC)c(OC)c1)c1cccc(OCC(=O)NCCNC(=O)COc2cccc(\[C@@H\](CCc3ccc(OC)c(OC)c3)OC(=O)\[C@@H\]3CCCCN3C(=O)\[C@@H\](CC)c3cc(OC)c(OC)c(OC)c3)c2)c1)c1cc(OC)c(OC)c(OC)c1

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL269259)

### Other names (15)

- 2 piperidinecarboxylic acid 1 2s 1 oxo 2 3 4 5 trimethoxyphenyl butyl 2 2 1 2 ethanediylbis imino 2 oxo 2 1 ethanediyl oxy 3 1 phenylene 1r 3 3 4 dimethoxyphenyl propylidene ester 2s 2 s
- 2-PIPERIDINECARBOXYLIC ACID, 1-((2S)-1-OXO-2-(3,4,5-TRIMETHOXYPHENYL)BUTYL)-, 2,2'-(1,2-ETHANEDIYLBIS(IMINO(2-OXO-2,1-ETHANEDIYL)OXY-3,1-PHENYLENE((1R)-3-(3,4-DIMETHOXYPHENYL)PROPYLIDENE))) ESTER, (2S,2'S)-
- ap 1903
- AP-1903
- ap1903
- AP1903
- rimiducid
- Rimiducid
- Rimiducid (AP1903)
- rimiducid \[INN\]
- RIMIDUCID \[USAN\]
- Rimiducid \[WHO-DD\]
- rimiducid inn
- rimiducid usan
- rimiducid who dd

## Identifiers

**CAS registry numbers**

- 195514-63-7

**ChEMBL ID**

CHEMBL269259

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL269259)

**InChIKey**

GQLCLPLEEOUJQC-ZTQDTCGGSA-N

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL269259)

**PubChem compound IDs**

- 16135625

**FDA ingredient codes (UNII)**

- H564L1W5J2

## Regulatory information

### Other regulatory facts

**First in class**

No

**Orphan designation**

No

## Pharmacology

### Investigated indications (12)

- **Condition**  
Leukemia, Lymphocytic, Chronic, B-Cell

**Highest recorded phase**  
1

**Condition identifier**  
EFO:0000095

**Subject identifier**  
D015451
- **Condition**  
Prostatic Neoplasms

**Highest recorded phase**  
1

**Condition identifier**  
EFO:0000196

**Subject identifier**  
D011471
- **Condition**  
Myelodysplastic Syndromes

**Highest recorded phase**  
1

**Condition identifier**  
EFO:0000198

**Subject identifier**  
D009190
- **Condition**  
Precursor Cell Lymphoblastic Leukemia-Lymphoma

**Highest recorded phase**  
1

**Condition identifier**  
EFO:0000220

**Subject identifier**  
D054198
- **Condition**  
Leukemia, Myeloid, Acute

**Highest recorded phase**  
1

**Condition identifier**  
EFO:0000222

**Subject identifier**  
D015470
- **Condition**  
Lymphoma

**Highest recorded phase**  
1

**Condition identifier**  
EFO:0000574

**Subject identifier**  
D008223
- **Condition**  
Neoplasms

**Highest recorded phase**  
1

**Condition identifier**  
EFO:0000616

**Subject identifier**  
D009369
- **Condition**  
Multiple Myeloma

**Highest recorded phase**  
1

**Condition identifier**  
EFO:0001378

**Subject identifier**  
D009101
- **Condition**  
Neoplasms

**Highest recorded phase**  
1

**Condition identifier**  
MONDO:0004992

**Subject identifier**  
D009369
- **Condition**  
Breast Neoplasms

**Highest recorded phase**  
1

**Condition identifier**  
MONDO:0007254

**Subject identifier**  
D001943
- **Condition**  
Prostatic Neoplasms, Castration-Resistant

**Highest recorded phase**  
1

**Condition identifier**  
MONDO:0008315

**Subject identifier**  
D064129
- **Condition**  
Hematologic Neoplasms

**Highest recorded phase**  
1

**Condition identifier**  
MONDO:0044881

**Subject identifier**  
D019337

### Open Targets indications (32)

- **Condition identifier**  
EFO\_0000616

**Highest recorded phase**  
1
- **Condition identifier**  
EFO\_0001378
- **Condition identifier**  
MONDO\_0002334

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0002571

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0004948

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0004952

**Highest recorded phase**  
2
- **Condition identifier**  
MONDO\_0004967

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0004992

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0005036

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0005059

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0005062

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0005072

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0005233

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0005556

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0005570

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0005575

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0006451

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0006456

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0006486

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0007254

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0007915

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0008315

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0009693

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0009807

**Highest recorded phase**  
1
- **Condition identifier**  
MONDO\_0009831

**Highest recorded phase**  
1

And 7 more, listed on the interactive page.

### Trial references (15)

- NCT00868595  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00868595)
- NCT01823978  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01823978)
- NCT02744287  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02744287)
- NCT01744223  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01744223)
- NCT02743611  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02743611)
- NCT03016377  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03016377)
- NCT03056339  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03056339)
- NCT02477878  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02477878)
- NCT03459170  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03459170)
- NCT02487459  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02487459)
- NCT02792114  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02792114)
- NCT03288493  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03288493)
- NCT03958656  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03958656)
- NCT04960579  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04960579)
- NCT06066424  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06066424)

## Chemical properties

**Calculated partition coefficient (XLogP)**

11.9

**Prodrug**

No

**Chirality**

Single enantiomer

**Inorganic**

No

**Heavy atoms**

102

**Molecular formula**

C78H98N4O20

**Monoisotopic mass**

1410.67744153

**Natural product**

No

## Evidence counts

**Recorded assays**

17

**Active assays**

4

### Active assay types (2)

- Confirmatory
- Screening

## Related records

### Trials (39)

- A Phase I Trial of T Cells Expressing an Anti-GD2 Chimeric Antigen Receptor in Children and Young Adults With GD2+ Solid Tumors
- A Study to Evaluate the Safety, Tolerability, Cellular Kinetics, Pharmacodynamics, and Efficacy of P-CD19CD20-ALLO1 in Participants With Severe, Treatment-refractory Systemic Lupus Erythematosus (SLE)
- Administration of Autologous CAR-T CD19 Antigen With Inducible Safety Switch in Patients With Relapsed/Refractory ALL
- Administration of Donor T Cells With the Caspase-9 Suicide Gene
- Anti-CD19 CAR-T Cells With Inducible Caspase 9 Safety Switch for B-cell Lymphoma
- BPX-501 T Cells Infused Post Stem Cell Transplant in Pediatrics With Non-Malignant Disorders Ineligible for BPU004 Study
- Compassionate Use of CAR T Cells Targeting the CD19 Antigen and Containing the Inducible Caspase 9 Safety Switch
- Donor Lymphocyte Infusion (DLI) of T-cells Genetically Modified With iCasp9 Suicide Gene
- Dose Escalation and Expansion Study of TROP2 CAR Engineered IL-15- Transduced Cord Blood-derived NK Cells in Combination With Cetuximab in Patient With Colorectal Cancer (CRC) With Minimal Residual Disease (MRD)
- Long Term Follow-up Study for Patients Enrolled on the BP-004 Clinical Study
- Long-Term Follow-Up Study for Subjects Treated With P-BCMA-101
- MTD Study of Vaccine BP-GMAX-CD1 Plus AP1903 to Treat Castrate Resistant Prostate Cancer
- P-BCMA-101 Tscm CAR-T Cells in the Treatment of Patients With Multiple Myeloma (MM)
- [P-BCMA-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With Multiple Myeloma](https://trialight.com/data/trial/p-bcma-allo1-allogeneic-car-t-cells-in-the-treatment-of-e2ccd391-aae5-46af-8f6a-c62271620514.md)
- P-CD19CD20-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With B Cell Malignancies
- [P-MUC1C-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With Advanced or Metastatic Solid Tumors](https://trialight.com/data/trial/p-muc1c-allo1-allogeneic-car-t-cells-in-the-treatment-of-3b621ad1-a285-4f47-9560-9899dc747f7a.md)
- P-PSMA-101 CAR-T Cells in the Treatment of Subjects With Metastatic Castration-Resistant Prostate Cancer (mCRPC) and Advanced Salivary Gland Cancers (SGC)
- Phase 1 Dose Escalation and Expansion Study of TROP2 CAR Engineered IL15-transduced Cord Blood-derived NK Cells in Patients With Advanced Solid Tumors (TROPIKANA)
- Phase 1/2 Window Of Opportunity Study Of TROP2 CAR/IL-15 TGFBR2 KO NK Cells Delivered Intraperitoneally For The Management Of Gastric Cancer Metastatic To The Peritoneum
- Phase 1b Study Of TRICK-NK In Combination With T-Dxd In Treatment-Refractory Breast Cancers

### In development for (12)

- Acute lymphoblastic leukemia Phase 1
- [Acute myeloid leukemia](https://trialight.com/data/condition/acute-myeloid-leukemia-b0971a7a-c18d-544e-bd7f-b1a13b9caa30.md) Phase 1
- [B-cell chronic lymphocytic leukemia](https://trialight.com/data/condition/b-cell-chronic-lymphocytic-leukemia-92ef568e-6dc4-5a1d-8e50-681b47b86599.md) Phase 1
- [Breast cancer](https://trialight.com/data/condition/breast-cancer-8ac10da3-93bd-54c5-a93b-265bc6699689.md) Phase 1
- [Cancer](https://trialight.com/data/condition/cancer-703b1dfc-4812-50eb-83f4-d7a205d16bdb.md) Phase 1
- [Hematopoietic and lymphoid cell neoplasm](https://trialight.com/data/condition/hematopoietic-and-lymphoid-cell-neoplasm-ed3616fa-22fe-5984-94b4-745416e01ef9.md) Phase 1
- [Lymphoma](https://trialight.com/data/condition/lymphoma-de4db685-7419-5e0e-b958-4591ffd69d43.md) Phase 1
- [Metastatic prostate carcinoma](https://trialight.com/data/condition/metastatic-prostate-carcinoma-d5fb1084-bad5-5db6-8240-897dc47ea451.md) Phase 1
- [Myelodysplastic syndrome](https://trialight.com/data/condition/myelodysplastic-syndrome-f5df8ce5-6064-53d3-902c-f09fc4acd4bb.md) Phase 1
- Neoplasm Phase 1
- [Plasma cell myeloma](https://trialight.com/data/condition/plasma-cell-myeloma-37186689-2591-5775-9042-2f2bf046a2b5.md) Phase 1
- [Prostate cancer](https://trialight.com/data/condition/prostate-cancer-3659fc70-617b-5868-a093-ae819ffc6755.md) Phase 1

---

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