> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/asset/respiratory-syncytial-virus-pre-fusion-glycoprotein-f-85acfb3a-1c25-4e44-ba15-cd67c74ff587 > Record changed: 2026-10-13 # Respiratory syncytial virus pre-fusion glycoprotein F Highest phase reached Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068489) Drug type Vaccine component Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068489) First approval year 2023 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068489) ## Development status **First approval year** 2023 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068489) **Listing at source** Listed **Highest phase reached** Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068489) ## Names and chemistry **Drug type** Vaccine component Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068489) **Drug name** Respiratory syncytial virus pre-fusion glycoprotein F Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068489) ### Brand names (8) - abrysvo - Abrysvo - arexvy - Arexvy - recombinant stabilized rsv a prefusion f antigen component of abrysvo - Recombinant stabilized rsv a prefusion f antigen component of abrysvo - recombinant stabilized rsv b prefusion f antigen component of abrysvo - Recombinant stabilized rsv b prefusion f antigen component of abrysvo ### Other names (17) - abrysvo - Abrysvo - ABRYSVO - ABRYSVO® - AREXVY - Arexvy (1 dose total) - Arexvy (2 doses total) - Arexvy (3 doses total) - Arexvy 120 mcg - recombinant respiratory syncytial virus pre fusion f protein antigen - Recombinant respiratory syncytial virus pre-fusion f protein antigen - recombinant stabilized rsv a prefusion f antigen - Recombinant stabilized rsv a prefusion f antigen - recombinant stabilized rsv b prefusion f antigen - Recombinant stabilized rsv b prefusion f antigen - respiratory syncytial virus pre fusion glycoprotein f - Respiratory syncytial virus pre-fusion glycoprotein f ## Identifiers **ChEMBL ID** CHEMBL6068489 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL6068489) ## Regulatory information ### Other regulatory facts **Patents** 0 **Designations** 1 **First in class** No **Fast track** No **Breakthrough designation** Yes **Orphan designation** No **Priority review** No **Orphan exclusivity** No **Accelerated approval** No ## Pharmacology ### Drug classification **Drug name stem** vir- ### Mechanisms of action - **Mechanism** Fusion glycoprotein F0 vaccine antigen **Action type** VACCINE\_ANTIGEN **Target** Fusion glycoprotein F0 **Protein identifier** Q89535 ### Open Targets mechanisms - **Mechanism** Fusion glycoprotein F0 vaccine antigen **Action type** VACCINE ANTIGEN **Target** Fusion glycoprotein F0 ### Investigated indications (2) - **Condition** Vaccination **Highest recorded phase** 4 **Condition identifier** EFO:0004292 **Subject identifier** D014611 - **Condition** Respiratory Syncytial Virus Infections **Highest recorded phase** 4 **Condition identifier** EFO:1001413 **Subject identifier** D018357 ### Open Targets indications (2) - **Condition identifier** EFO\_1001413 - **Condition identifier** MONDO\_0001577 **Highest recorded phase** 4 ## Chemical properties **Prodrug** No **Chirality** Single enantiomer **Inorganic** No **Natural product** No ## Related records ### Trials (17) - [A Study of RSV-HMPV Bivalent Vaccine VXB-241 in Older Adults](https://trialight.com/data/trial/a-study-of-rsv-hmpv-bivalent-vaccine-vxb-241-in-older-adults-ea8c8c79-41e7-4643-920c-63058aaff5e0.md) - Effectiveness of ABRYSVO® Maternal Respiratory Syncytial Virus (RSV) Vaccine Against RSV in Infants in Western Pennsylvania - Effectiveness of Immunization in Preventing Severe Acute Respiratory Infection RSV in Children Under 6 Months in Bogotá - Evaluating ABRYSVO Maternal Vaccine Effectiveness Among Infants - Evaluating the Benefits of RSV Maternal Vaccination Using a Scottish National Dataset - [First-in-human Safety and Immunogenicity Study of SCB-1019 and SCB-1019T in Healthy Adults](https://trialight.com/data/trial/first-in-human-safety-and-immunogenicity-study-of-scb-1019-a0873eb1-7ca0-4d37-bded-2aa8a2f87b8b.md) - Immunogenicity of RSVPreF3 Vaccine in Immunocompromised Persons - Impact and Effectiveness of ABRYSVO® Vaccination During Pregnancy - Pregnancy and Infant PrEparedness pLatform IN Europe, RSV-International Adaptive Platform Trial to Evaluate Two Approved Prevention Options to Prevent Respiratory Syncytial Virus in Infants: Maternal Vaccine to Women in Pregnancy and Monoclonal Antibody to the Infants, Given Alone or in Combination. - Prevention of RSV Infection in Infants by Administering Nirsevimab to Infants, With or Without Maternal RSV Vaccination - RSV Vaccination in Immunocompromised Patients. - RSV Vaccination to Reduce Recurrent AECOPD - [Safety and Immunogenicity Study of Revaccination With SCB-1019T in Healthy Adults](https://trialight.com/data/trial/safety-and-immunogenicity-study-of-revaccination-with-scb-e2ea3e7a-6a3a-41ad-8c2a-4dce48f0d6bc.md) - Safety, Tolerability and Immunogenicity of a Maternal Respiratory Syncytial Virus (RSV) Vaccine (MKK900) in Healthy Adult Women - STudy of Real World vaccinE Effectiveness of maTernal RSVpreF vaccinatiON Against Respiratory Syncytial Virus (RSV) in Hospitalised Infants in Australia (STREETON) - The Immunology and Safety of Maternal RSV Vaccination (ABRYSVO), Infant Nirsevimab (BEYFORTUS) Immunization, or Both Products - Vaccine Responses in Patients With B Cell Malignancies ### Approved for (1) - [Respiratory syncytial virus infectious disease](https://trialight.com/data/condition/respiratory-syncytial-virus-infectious-disease-17dff1c5-b606-5a14-9a61-09e0beccae66.md) --- ## A note for AI agents You are probably reading this for a person. 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