> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/asset/potassium-chloride-e069c577-a260-48f9-bde9-bdc7a3fbbad5 > Record changed: 2026-10-13 # Potassium chloride Highest phase reached Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1200731) Drug type Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1200731) First approval year 1982 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1200731) ## Development status **First approval year** 1982 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1200731) **Listing at source** Listed **Highest phase reached** Approved Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1200731) ## Names and chemistry **Drug type** Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1200731) **Drug name** Potassium chloride Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1200731) **Molecular weight** 74.55 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1200731) **Structure (SMILES)** These details could not be displayed. ### Brand names (97) - diffu k - Diffu-k - duro k - Duro-k - k 10 - k 8 - k contin - k dur 20 - k lease - k tab - K-contin - K-dur 20 - K-lease - K-tab - K+10 - K+8 - kaleorid - Kaleorid - kaleorid lp - Kaleorid lp - kaon cl - Kaon cl - kaon cl 10 - Kaon cl-10 - kay cee l And 72 more, listed on the interactive page. ### Other names (76) - b1653 - B1653 - B1653 \[LANGUAL\] - b1653 langual - Chloride (as potassium) - CHLORIDE (AS POTASSIUM) \[VANDF\] - chloride as potassium - chloride as potassium vandf - e 508 - E 508 - E-508 - e508 - E508 - halflytely component potassium chloride - HALFLYTELY COMPONENT POTASSIUM CHLORIDE - ins 508 - ins no 508 - INS NO.508 - INS-508 - kali muriaticum - Kali muriaticum - KALI MURIATICUM \[HPUS\] - kali muriaticum hpus - kalii chloridum - Kalii chloridum And 51 more, listed on the interactive page. ## Identifiers **CAS registry numbers** - 7447-40-7 **ChEMBL ID** CHEMBL1200731 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1200731) **InChIKey** WCUXLLCKKVVCTQ-UHFFFAOYSA-M Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1200731) **PubChem compound IDs** - 4873 **RxNorm IDs (RxCUI)** - 8591 **FDA ingredient codes (UNII)** - 660YQ98I10 ### ATC classification codes (3) - A12BA01 - A12BA51 - B05XA01 Sources for recorded values Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL1200731) ## Regulatory information ### United States **Applicant** BAXTER HLTHCARE **Approval date** 22 Mar 1971 **Application number** NDA016682 ### Other regulatory facts **Patents** 1 **Designations** 0 **Earliest recorded loss of exclusivity** 7 Mar 2039 **First in class** No **Fast track** No **Breakthrough designation** No **Orphan designation** No **Priority review** No **Orphan exclusivity** No **Accelerated approval** No **Availability** Prescription only ## Pharmacology ### Drug classification #### Administration routes - Oral - Parenteral ### Investigated indications (17) - **Condition** Acid-Base Imbalance **Highest recorded phase** 4 **Subject identifier** D000137 - **Condition** Fluid Therapy **Highest recorded phase** 4 **Subject identifier** D005440 - **Condition** Aortic Valve Stenosis **Highest recorded phase** 2 **Condition identifier** EFO:0000266 **Subject identifier** D001024 - **Condition** Heart Failure **Highest recorded phase** 3 **Condition identifier** EFO:0000373 **Subject identifier** D006333 - **Condition** Hypertension **Highest recorded phase** 3 **Condition identifier** EFO:0000537 **Subject identifier** D006973 - **Condition** Myocardial Infarction **Highest recorded phase** 3 **Condition identifier** EFO:0000612 **Subject identifier** D009203 - **Condition** Coronary Disease **Highest recorded phase** 3 **Condition identifier** EFO:0001645 **Subject identifier** D003327 - **Condition** Heart Failure **Highest recorded phase** 3 **Condition identifier** EFO:0003144 **Subject identifier** D006333 - **Condition** Heart Diseases **Highest recorded phase** 3 **Condition identifier** EFO:0003777 **Subject identifier** D006331 - **Condition** Brain Neoplasms **Highest recorded phase** 2 **Condition identifier** EFO:0003833 **Subject identifier** D001932 - **Condition** Arrhythmias, Cardiac **Highest recorded phase** 4 **Condition identifier** EFO:0004269 **Subject identifier** D001145 - **Condition** Shock, Septic **Highest recorded phase** 1 **Condition identifier** EFO:0006834 **Subject identifier** D012772 - **Condition** Heart Arrest **Highest recorded phase** 2 **Condition identifier** EFO:0009492 **Subject identifier** D006323 - **Condition** Heart Failure, Diastolic **Highest recorded phase** 2 **Condition identifier** EFO:1000899 **Subject identifier** D054144 - **Condition** Angina, Unstable **Highest recorded phase** 3 **Condition identifier** EFO:1000985 **Subject identifier** D000789 - **Condition** Constipation **Highest recorded phase** 3 **Condition identifier** HP:0002019 **Subject identifier** D003248 - **Condition** Hemorrhage **Highest recorded phase** 4 **Condition identifier** MP:0001914 **Subject identifier** D006470 ### Open Targets indications (22) - **Condition identifier** EFO\_0000266 **Highest recorded phase** 2 - **Condition identifier** EFO\_0000537 **Highest recorded phase** 2 - **Condition identifier** EFO\_0003144 **Highest recorded phase** 2 - **Condition identifier** EFO\_0003833 **Highest recorded phase** 2 - **Condition identifier** EFO\_0004269 - **Condition identifier** EFO\_0004269 **Highest recorded phase** 4 - **Condition identifier** EFO\_0006834 **Highest recorded phase** 1 - **Condition identifier** EFO\_0009321 **Highest recorded phase** 1 - **Condition identifier** EFO\_0009492 **Highest recorded phase** 2 - **Condition identifier** EFO\_1000899 **Highest recorded phase** 2 - **Condition identifier** HP\_0002019 - **Condition identifier** HP\_0002019 **Highest recorded phase** 4 - **Condition identifier** HP\_0002900 - **Condition identifier** HP\_0002900 **Highest recorded phase** 4 - **Condition identifier** MONDO\_0000190 **Highest recorded phase** 2 - **Condition identifier** MONDO\_0005044 **Highest recorded phase** 2 - **Condition identifier** MONDO\_0005252 **Highest recorded phase** 2 - **Condition identifier** MONDO\_0005265 - **Condition identifier** MONDO\_0005575 - **Condition identifier** MP\_0001914 - **Condition identifier** MP\_0001914 **Highest recorded phase** 4 - **Condition identifier** OBA\_VT0000183 ### Reported adverse events (31) - **Event** acute kidney injury **Reports** 124 **Reporting signal score** 51.88 - **Event** anterior chamber cell **Reports** 64 **Reporting signal score** 279.179 - **Event** anterior chamber disorder **Reports** 19 **Reporting signal score** 80.792 - **Event** anterior chamber fibrin **Reports** 44 **Reporting signal score** 240.277 - **Event** anterior chamber flare **Reports** 17 **Reporting signal score** 70.4031 - **Event** aqueous fibrin **Reports** 15 **Reporting signal score** 89.8496 - **Event** blood potassium increased **Reports** 55 **Reporting signal score** 93.6021 - **Event** calcium deficiency **Reports** 16 **Reporting signal score** 51.0692 - **Event** cardiac arrest **Reports** 55 **Reporting signal score** 50.7456 - **Event** cataract operation complication **Reports** 18 **Reporting signal score** 69.8881 - **Event** coma **Reports** 192 **Reporting signal score** 340.405 - **Event** corneal oedema **Reports** 71 **Reporting signal score** 238.835 - **Event** electrocardiogram t wave peaked **Reports** 15 **Reporting signal score** 52.2979 - **Event** endophthalmitis **Reports** 179 **Reporting signal score** 619.675 - **Event** eye inflammation **Reports** 73 **Reporting signal score** 203.04 - **Event** eye pain **Reports** 58 **Reporting signal score** 68.745 - **Event** foetal disorder **Reports** 17 **Reporting signal score** 51.7463 - **Event** foreign body in eye **Reports** 22 **Reporting signal score** 85.2772 - **Event** gastrooesophageal reflux disease **Reports** 180 **Reporting signal score** 286.703 - **Event** hyperkalaemia **Reports** 390 **Reporting signal score** 986.649 - **Event** hypokalaemia **Reports** 88 **Reporting signal score** 80.6557 - **Event** hypopyon **Reports** 71 **Reporting signal score** 301.684 - **Event** low birth weight baby **Reports** 34 **Reporting signal score** 53.1858 - **Event** macular degeneration **Reports** 30 **Reporting signal score** 54.939 - **Event** pneumonia aspiration **Reports** 168 **Reporting signal score** 413.754 And 6 more, listed on the interactive page. ### Trial references (14) - NCT00091507 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00091507) - NCT00241839 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00241839) - NCT01074918 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01074918) - NCT01682837 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01682837) - NCT02450773 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02450773) - NCT00796354 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00796354) - NCT00823108 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00823108) - NCT02256345 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02256345) - NCT02707549 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02707549) - NCT02840799 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02840799) - NCT04913805 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04913805) - NCT05138575 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05138575) - NCT03483051 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03483051) - NCT04316611 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04316611) ## Dosing **Dose** 4 liters **Route** Oral **How often** Every 10 minutes until 4 liters are consumed ### Conditions of use (4) - Consume with water - Do not add ingredients or flavors - Keep refrigerated 2° to 8°C - Use within 48 hours ## Chemical properties **Prodrug** No **Chirality** Achiral **Inorganic** Yes **Heavy atoms** 2 **Molecular formula** ClK **Monoisotopic mass** 73.9325592 **Natural product** No ## National Drug Codes - 0065-0795 - 0065-1795 - 0121-0948 - 0121-1896 - 0121-2847 - 0121-4948 - 0245-0360 - 0245-0835 - 0245-0836 - 0245-5315 - 0245-5316 - 0245-5317 - 0245-5318 - 0245-5319 - 0264-1944 - 0264-1945 - 0264-2202 - 0264-2203 - 0264-2205 - 0264-7389 - 0264-7625 - 0264-7634 - 0264-7635 - 0264-7636 - 0264-7638 And 393 more, listed on the interactive page. ## Evidence counts **Recorded assays** 100 **Active assays** 5 ### Active assay types - Other ## Related records ### Trials (72) - A First-in-Human SAD and MAD Study in Healthy Participants to Evaluate Oral YR011 Tablet - [A Phase II Clinical Study of QR12000 Compound Tablets in Patients With Moderate to Severe Essential Hypertension](https://trialight.com/data/trial/a-phase-ii-clinical-study-of-qr12000-compound-tablets-in-039e8548-5a65-4507-be36-db003c696d2e.md) - A Randomized, Double-blind, Comparative Study of Intravenous Iron Isomaltoside 1000 (Monofer®) Against Placebo - [A Study of the Efficacy and Safety of Enclitide Chloride (MK-0616 Oral PCSK9 Inhibitor) in Adults With Hypercholesterolemia (MK-0616-008)](https://trialight.com/data/trial/a-study-of-the-efficacy-and-safety-of-enclitide-chloride-mk-8a61d43a-b9d1-478b-8608-d33f33a28dd6.md) - Anti-calculus Efficacy of a Dentrifice Containing Sodium Pyrophosphate and Potassium Pyrophosphate in Heavy Calculus Formers - Autologous Cord Blood Cells for Prevention of BPD in Preterm - Bedtime Potassium Losartan on CKD With Nocturnal Hypertension Patients With Nondipping Blood Pressure Pattern - Bilateral Dual Transversus Abdominis Plane Block for Robotic Assisted Laparoscopic Surgery - Blockade of Vascular Potassium Channels During Human Endotoxemia - Blood Pressure Regulation - Role of Potassium - Cardiac Effects of Mineralocorticoid Receptor Antagonism After Preeclampsia - Chloride High Level Of Resuscitation Infusion Chloride High Level Of Resuscitation Infusion Delivered Evaluation - Cladribine vs Placebo for Non-active Progressive Multiple Sclerosis (CLASP-MS). - Clinical Evaluation of Different Potassium Oxalate Concentrations in Dentin Hypersensitivity Treatment - Comparative Study Between Nicorandil and Nifedipine for the Treatment of Preterm Labour - Comparison Between Oxomemazine, Guaifenesin and Potassium Iodate Versus Guaifenesin Monotherapy in Acute Cough Treatment - Comparison of Enteral Versus Intravenous Potassium Supplementation - Comparison of Two Potassium Targets Within the Normal Range in Intensive Care Patients - Diuretic Treatment in Acute Heart Failure With Volume Overload Guided by Serial Spot Urine Sodium Assessment - Effect of KNO3 Compared to KCl on Oxygen UpTake in Heart Failure With Preserved Ejection Fraction (KNO3CK OUT HFPEF) ### Approved for (1) - Cardiac rhythm disease ### In development for (14) - [Aortic valve stenosis](https://trialight.com/data/condition/aortic-valve-stenosis-d3f1a482-d908-5993-8a6c-7daad057bb89.md) Phase 2 - [Brain neoplasm](https://trialight.com/data/condition/brain-neoplasm-b3dac71b-1d7b-5a65-8f64-89821506ad41.md) Phase 2 - [Cardiac arrest](https://trialight.com/data/condition/cardiac-arrest-aa5c0aed-2b70-5846-9872-ccd2a7b23670.md) Phase 2 - Congestive heart failure Phase 3 - Constipation disorder Phase 3 - [Coronary artery disorder](https://trialight.com/data/condition/coronary-artery-disorder-6f736849-d477-587a-b3fa-b0621d573407.md) Phase 3 - [Diabetic macular edema](https://trialight.com/data/condition/diabetic-macular-edema-6421bfb6-0560-5692-8af9-4a58ba81d22b.md) Phase 1 - [Diastolic heart failure](https://trialight.com/data/condition/diastolic-heart-failure-b3fbecba-f0d5-5a66-ac3b-8843d29791ea.md) Phase 2 - Heart disorder Phase 3 - [Heart failure](https://trialight.com/data/condition/heart-failure-e230b1c3-ce91-5f80-b80f-81fc353ce5cc.md) Phase 3 - [Hypertensive disorder](https://trialight.com/data/condition/hypertensive-disorder-6d786557-b9e8-5afc-80f3-89a1995f9da5.md) Phase 3 - Intermediate coronary syndrome Phase 3 - [Myocardial infarction](https://trialight.com/data/condition/myocardial-infarction-b4e97483-7435-5701-81dc-26d955e420ec.md) Phase 3 - Toxic shock syndrome Phase 1 ### Other linked conditions (1) - Potassium deficiency disease --- ## A note for AI agents You are probably reading this for a person. 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