> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/asset/poliovirus-vaccine-live-oral-b8a2c29f-68a8-42e2-8061-44e2b1bbdc3e > Record changed: 2026-11-04 # Poliovirus vaccine live oral Highest phase reached Phase 3 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2108778) Drug type Vaccine component Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2108778) ## Development status **Listing at source** Listed **Highest phase reached** Phase 3 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2108778) ## Names and chemistry **Drug type** Vaccine component Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2108778) **Drug name** Poliovirus vaccine live oral Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2108778) ### Other names (2) - poliovirus vaccine live oral - Poliovirus vaccine live oral ## Identifiers **ChEMBL ID** CHEMBL2108778 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2108778) ## Regulatory information ### Other regulatory facts **First in class** No **Orphan designation** No ## Pharmacology ### Drug classification **Drug name stem** \-vir- ### Investigated indications (4) - **Condition** Severe Acute Respiratory Syndrome **Highest recorded phase** 3 **Condition identifier** EFO:0000694 **Subject identifier** D045169 - **Condition** Malaria **Highest recorded phase** 1 **Condition identifier** EFO:0001068 **Subject identifier** D008288 - **Condition** Poliomyelitis **Highest recorded phase** 2 **Condition identifier** EFO:0007450 **Subject identifier** D011051 - **Condition** Severe Acute Respiratory Syndrome **Highest recorded phase** 3 **Condition identifier** MONDO:0100096 **Subject identifier** D045169 ### Open Targets indications (3) - **Condition identifier** EFO\_0000694 **Highest recorded phase** 3 - **Condition identifier** EFO\_0007450 **Highest recorded phase** 2 - **Condition identifier** MONDO\_0100096 **Highest recorded phase** 3 ### Trial references (5) - NCT03554798 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03554798) - NCT04232943 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04232943) - NCT04529538 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04529538) - NCT04540185 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04540185) - NCT05155579 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05155579) ## Chemical properties **Prodrug** No **Chirality** Single enantiomer **Inorganic** No **Natural product** No ## Related records ### Trials (30) - A Phase 3 Randomized Double Blind Efficacy and Safety Study of Oral Polio Vaccine and NA-831 for Covid-19 - A Study to Evaluate Safety and Immunogenicity of tOPV in 1 to 5 Years and at 6 Weeks of Age - A Study to Evaluate the Safety and Immunogenicity of Oral Polio Vaccine Type 2 in Infants and Children - [A Study to Evaluate the Safety and Immunogenicity of VLP-Polio in Infants and Toddlers](https://trialight.com/data/trial/a-study-to-evaluate-the-safety-and-immunogenicity-of-vlp-226caa7e-ece8-4568-aef3-43e4ce57b6fc.md) - An Extension to Study MALARIA-055 PRI (NCT00866619) to Evaluate the Long-term Efficacy, Safety and Immunogenicity of GSK Biologicals' Candidate Malaria Vaccine in Infants and Children in Africa - Assessment of Safety and Immunogenicity of a Single Vial Presentation of R21/Matrix-M and Co-Administration With EPI Vaccines - Comparison of DTaP-HB-PRP~T Combined Vaccine to Tritanrix-HepB/Hib™, Both Given Concomitantly With Oral Polio Vaccine - Concomitant Use and Staggered Use of Vaccine and Oral Poliovirus (OPV) in Healthy Infants (V260-014)(COMPLETED) - Diarrhea and Bivalent Oral Polio Vaccine Immunity - Efficacy of GSK Biologicals' Candidate Malaria Vaccine 257049 Against Malaria Disease in Infants and Children in Africa - Immunogenicity and Safety Study of GlaxoSmithKline Biologicals' Poliorix™ Vaccine - Immunogenicity of Co-administered Oral Polio Vaccine and Oral Cholera Vaccine - Immunogenicity of Different Primary Immunization Schedules with Inactivated Poliovirus Vaccine (IPV) Plus Pentavalent Vaccine (DTwP-HBV-Hib) or with Hexavalent Vaccine (DTwP-HBV-Hib-IPV) - Immunogenicity of Inactivated and Live Polio Vaccines - Immunogenicity Study of Antibody Persistence and Booster Effect of DTaP-HB PRP~T Combined Vaccine in Filipino Infants - Immunogenicity Study of Antibody Persistence and Booster Effect of DTaP-HB-PRP~T Combined Vaccine or Tritanrix-HepB/Hib™ - Investigating the Mortality and the Morbidity Impact of Oral Polio Vaccine at Birth - IPV in Moderate to Severe Chronic Malnourished 9-12 Month Old Children in Karachi. - Safety and Immunogenicity of 1 or 2 Doses of IPV in Latin American Infants Primed With Bivalent OPV Vaccine - Study of a Novel Type 1 Oral Poliomyelitis Vaccine in Bangladesh ### In development for (4) - [COVID-19](https://trialight.com/data/condition/covid-19-13f0ebf3-c291-557d-bdef-93563d077103.md) Phase 3 - [Malaria](https://trialight.com/data/condition/malaria-54828cac-9b96-5833-93e2-e012d4505853.md) Phase 1 - [Poliomyelitis](https://trialight.com/data/condition/poliomyelitis-5f8120f0-b67f-5e12-862f-914f03ab5ac7.md) Phase 2 - [Severe acute respiratory syndrome](https://trialight.com/data/condition/severe-acute-respiratory-syndrome-7654d02a-f750-52a0-bec2-afe3b4b3c224.md) Phase 3 --- ## A note for AI agents You are probably reading this for a person. 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