> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/asset/poliovirus-vaccine-inactivated-73d8bd8f-cda2-4090-885b-f54c53ea52ef
> Record changed: 2026-10-13

# Poliovirus vaccine inactivated

Highest phase reached

Phase 3

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2107962)

Drug type

Vaccine component

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2107962)

## Development status

**Listing at source**

Listed

**Highest phase reached**

Phase 3

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2107962)

## Names and chemistry

**Drug type**

Vaccine component

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2107962)

**Drug name**

Poliovirus vaccine inactivated

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2107962)

### Other names (8)

- opvero oral poliomyelitis vaccine
- oral poliomyelitis vaccine
- Oral Poliomyelitis Vaccine
- Oral poliomyelitis vaccine (OPV)
- poliomyelitis vaccine
- Poliomyelitis vaccine
- poliovirus vaccine inactivated
- Poliovirus vaccine inactivated

## Identifiers

**ChEMBL ID**

CHEMBL2107962

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2107962)

## Regulatory information

### Other regulatory facts

**First in class**

No

**Orphan designation**

No

## Pharmacology

### Drug classification

**Drug name stem**

\-vir-

### Investigated indications (7)

- **Condition**  
Virus Diseases

**Highest recorded phase**  
3

**Condition identifier**  
EFO:0000763

**Subject identifier**  
D014777
- **Condition**  
Malaria

**Highest recorded phase**  
1

**Condition identifier**  
EFO:0001068

**Subject identifier**  
D008288
- **Condition**  
Rotavirus Infections

**Highest recorded phase**  
3

**Condition identifier**  
EFO:0002622

**Subject identifier**  
D012400
- **Condition**  
Meningococcal Infections

**Highest recorded phase**  
3

**Condition identifier**  
EFO:0004249

**Subject identifier**  
D008589
- **Condition**  
Poliomyelitis

**Highest recorded phase**  
3

**Condition identifier**  
EFO:0007450

**Subject identifier**  
D011051
- **Condition**  
Postpoliomyelitis Syndrome

**Highest recorded phase**  
2

**Condition identifier**  
EFO:0007454

**Subject identifier**  
D016262
- **Condition**  
Gastroenteritis

**Highest recorded phase**  
3

**Condition identifier**  
EFO:1001463

**Subject identifier**  
D005759

### Open Targets indications (5)

- **Condition identifier**  
EFO\_0000763

**Highest recorded phase**  
3
- **Condition identifier**  
EFO\_0002622

**Highest recorded phase**  
3
- **Condition identifier**  
EFO\_0007450

**Highest recorded phase**  
3
- **Condition identifier**  
EFO\_0007454

**Highest recorded phase**  
2
- **Condition identifier**  
EFO\_1001463

**Highest recorded phase**  
3

### Reported adverse events

- **Event**  
vaccination complication

**Reports**  
1

**Reporting signal score**

8.81946

### Trial references (38)

- NCT00258843  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00258843)
- NCT00348387  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00348387)
- NCT00604058  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00604058)
- NCT01048190  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01048190)
- NCT01056705  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01056705)
- NCT01510366  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01510366)
- NCT01708720  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01708720)
- NCT01709071  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01709071)
- NCT01813604  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01813604)
- NCT02111135  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02111135)
- NCT02231632  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02231632)
- NCT02291263  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02291263)
- NCT02347423  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02347423)
- NCT02434770  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02434770)
- NCT02985320  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02985320)
- NCT03016949  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03016949)
- NCT03025750  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03025750)
- NCT03032419  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03032419)
- NCT03092791  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03092791)
- NCT03169725  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03169725)
- NCT03239496  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03239496)
- NCT03526978  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03526978)
- NCT03671616  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03671616)
- NCT04232943  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04232943)
- NCT04264598  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04264598)

And 13 more, listed on the interactive page.

## Chemical properties

**Prodrug**

No

**Chirality**

Single enantiomer

**Inorganic**

No

**Natural product**

No

## Related records

### Trials (37)

- A Clinical Study to Evaluate the Safety and Immunogenicity of Inactivated Poliomyelitis Vaccine in Healthy Infants
- [A Phase 3 Study of BIBP Diphtheria, Tetanus and Acellular Pertussis (Three Components) Combined Vaccine, Adsorbed](https://trialight.com/data/trial/a-phase-3-study-of-bibp-diphtheria-tetanus-and-acellular-eb67211b-e1c8-496f-b12f-7f021c930777.md)
- A Post-marketing Safety Study of GSK Bio IPV Vaccine (PoliorixTM) in Korean Children
- A Study to Evaluate the Safety and Immunogenicity of Recombinant Trivalent Poliomyelitis Vaccine (Sf-RVN Cell) in Healthy Adults
- Assessment of Safety and Immunogenicity of a Single Vial Presentation of R21/Matrix-M and Co-Administration With EPI Vaccines
- [Co-administration Study of an Investigational Live-Attenuated Respiratory Syncytial Virus Vaccine in Infants and Toddlers](https://trialight.com/data/trial/co-administration-study-of-an-investigational-live-7909bc3c-d5cb-4ef7-9416-19caf2e95f7f.md)
- Comparison of DTaP-HB-PRP~T Combined Vaccine to Tritanrix-HepB/Hib™, Both Given Concomitantly With Oral Polio Vaccine
- Concomitant Use and Staggered Use of Vaccine and Oral Poliovirus (OPV) in Healthy Infants (V260-014)(COMPLETED)
- Efficacy, Safety, and Immunogenicity of V260 in Healthy Chinese Infants (V260-024)
- Immunogenicity and Reactogenicity of DTPa-HBV-IPV/Hib Vaccine Followed by the Same Vaccine and Oral Polio Vaccine
- Immunogenicity and Safety of a Quadrivalent Meningococcal Conjugate Vaccine in Infants and Toddlers When Administered Concomitantly With Routine Pediatric Vaccines in the United Kingdom
- [Immunogenicity and Safety of Diphtheria, Tetanus, Pertussis (DTaP) Vaccine in 3-month-old Infants](https://trialight.com/data/trial/immunogenicity-and-safety-of-diphtheria-tetanus-pertussis-9972a9a1-b333-4eb6-8a8a-4edf642c9153.md)
- Immunogenicity and Safety of Imovax Polio in Chinese Infants Compared to Local OPV
- Immunogenicity and Safety of Liquid Bivalent Oral Poliomyelitis Vaccine
- Inactivated Poliomyelitis Vaccine Made From Sabin Strain
- Inactivated Poliovirus Vaccine (IPV) With or Without E.Coli Double Mutant Heat-Labile Toxin (dmLT) Challenge Study in Healthy Adults
- Intradermal Fractional Dose IPV (fIPV) in Combination With dmLT
- Live Enterovirus Vaccine and Type 1 Diabetes
- Phase I Clinical Trial of Diphtheria, Tetanus and Acellular Pertussis (Three Components) Combined Vaccine, Adsorbed .
- Phase III Study on Rotavirus Vaccine to Evaluate Lot-to-lot Consistency and Interference With Routine UIP Immunization

### In development for (7)

- [Gastroenteritis](https://trialight.com/data/condition/gastroenteritis-6f158f22-dfd3-577b-847d-64d9cf80af87.md) Phase 3
- [Malaria](https://trialight.com/data/condition/malaria-54828cac-9b96-5833-93e2-e012d4505853.md) Phase 1
- [Meningococcal infection](https://trialight.com/data/condition/meningococcal-infection-127e031a-0256-5064-a935-b84efd154e0d.md) Phase 3
- [Poliomyelitis](https://trialight.com/data/condition/poliomyelitis-5f8120f0-b67f-5e12-862f-914f03ab5ac7.md) Phase 3
- Postpoliomyelitis syndrome Phase 2
- [Rotavirus infection](https://trialight.com/data/condition/rotavirus-infection-7e79da16-09e8-58fb-861e-f85f158082a6.md) Phase 3
- [Viral infectious disease](https://trialight.com/data/condition/viral-infectious-disease-43db42a3-adad-5b9d-b74c-f17df0674c21.md) Phase 3

---

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