> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/asset/petrelintide-b3738a49-6b24-44d3-b78a-1cda49db7323
> Record changed: 2026-10-13

# Petrelintide

Highest phase reached

Phase 2

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL5314864)

Drug type

Protein

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL5314864)

## Development status

**Listing at source**

Listed

**Highest phase reached**

Phase 2

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL5314864)

## Names and chemistry

**Drug type**

Protein

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL5314864)

**Drug name**

Petrelintide

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL5314864)

### Other names (15)

- petrelintida
- Petrelintida
- petrelintide
- Petrelintide
- petrelintide \[INN\]
- PETRELINTIDE \[USAN\]
- Petrelintide \[WHO-DD\]
- petrelintide inn
- petrelintide usan
- petrelintide who dd
- zp 8396
- ZP-8396
- zp8396
- Zp8396
- ZP8396

## Identifiers

**CAS registry numbers**

- 2766385-23-1

**ChEMBL ID**

CHEMBL5314864

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL5314864)

**FDA ingredient codes (UNII)**

- D78KBY7BRU

## Regulatory information

### Other regulatory facts

**First in class**

No

**Orphan designation**

No

## Pharmacology

### Drug classification

**Pharmacology name**

petrelintide

**Type**

Peptide

**Drug name stem**

\-tide

### Investigated indications

- **Condition**  
Obesity

**Highest recorded phase**  
1

**Condition identifier**  
EFO:0001073

**Subject identifier**  
D009765

### Open Targets indications (5)

- **Condition identifier**  
EFO\_0001073

**Highest recorded phase**  
2
- **Condition identifier**  
HP\_0001513

**Highest recorded phase**  
2
- **Condition identifier**  
HP\_0025502

**Highest recorded phase**  
1
- **Condition identifier**  
HP\_0025502

**Highest recorded phase**  
2
- **Condition identifier**  
MONDO\_0005148

**Highest recorded phase**  
2

### Trial references (2)

- NCT05096598  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05096598)
- NCT05613387  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05613387)

## Chemical properties

**Prodrug**

No

**Chirality**

Single enantiomer

**Inorganic**

No

**Natural product**

No

## Related records

### Trials (8)

- [A Dose-Finding Study of Petrelintide With Enicepatide (RO7795068) in Adults With Obesity or Overweight](https://trialight.com/data/trial/a-dose-finding-study-of-petrelintide-with-enicepatide-82c5f053-ec8a-4668-9e0a-622c279ae4b0.md)
- A First-in-human Study Looking at the Safety of ZP8396 and How it Works in the Body of Healthy Trial Participants
- A Research Study Looking at the Safety of Multiple Doses of ZP8396 and How it Works in the Body of Healthy Participants
- Efficacy and Safety of Petrelintide in Participants With Overweight or Obesity and Type 2 Diabetes (ZUPREME 2)
- Investigating the Pharmacokinetics of Petrelintide Using Different Drug Product Concentrations
- [Once-weekly Petrelintide Versus Placebo for Obesity or Overweight With Co-morbidities](https://trialight.com/data/trial/once-weekly-petrelintide-versus-placebo-for-obesity-or-ef0d6475-9d88-4275-801a-e48fda3f9f4a.md)
- Pharmacokinetics of Petrelintide Following Administration to Participants With Impaired Renal Function
- Pharmacokinetics of Petrelintide in Participants With Impaired Hepatic Function

### In development for (1)

- [Obesity disorder](https://trialight.com/data/condition/obesity-disorder-f3b57dc0-68ac-555c-8f13-0d81e595d9cb.md) Phase 1

---

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