> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/asset/pertussis-vaccine-7610d9a7-aaed-48b6-8e98-6edf96a989e9
> Record changed: 2026-10-13

# Pertussis vaccine

Highest phase reached

Phase 3

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2109219)

Drug type

Vaccine component

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2109219)

## Development status

**Listing at source**

Listed

**Highest phase reached**

Phase 3

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2109219)

## Names and chemistry

**Drug type**

Vaccine component

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2109219)

**Drug name**

Pertussis vaccine

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2109219)

### Other names (14)

- adsorbed purified pertussis vaccine
- Adsorbed purified pertussis vaccine
- bordetella pertussis
- Bordetella pertussis
- haemophilus pertussis whole
- Haemophilus pertussis whole
- hemophilus pertussis whole
- Hemophilus pertussis whole
- microbe de la coqueluche whole
- Microbe de la coqueluche whole
- pertussis purified antigen
- pertussis vaccine
- Pertussis vaccine
- Pertussis, purified antigen

## Identifiers

**ChEMBL ID**

CHEMBL2109219

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2109219)

**RxNorm IDs (RxCUI)**

- 8080

### ATC classification codes (2)

- J07AJ02
- J07AJ52

Sources for recorded values

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2109219)

## Regulatory information

### Other regulatory facts

**First in class**

No

**Orphan designation**

No

## Pharmacology

### Investigated indications (9)

- **Condition**  
Whooping Cough

**Highest recorded phase**  
3

**Condition identifier**  
EFO:0000650

**Subject identifier**  
D014917
- **Condition**  
Pneumococcal Infections

**Highest recorded phase**  
1

**Condition identifier**  
EFO:0000772

**Subject identifier**  
D011008
- **Condition**  
Multiple Sclerosis, Relapsing-Remitting

**Highest recorded phase**  
3

**Condition identifier**  
EFO:0003929

**Subject identifier**  
D020529
- **Condition**  
Tetanus

**Highest recorded phase**  
3

**Condition identifier**  
EFO:0005593

**Subject identifier**  
D013742
- **Condition**  
Typhoid Fever

**Highest recorded phase**  
1

**Condition identifier**  
EFO:0006789

**Subject identifier**  
D014435
- **Condition**  
Meningitis, Meningococcal

**Highest recorded phase**  
3

**Condition identifier**  
EFO:1001040

**Subject identifier**  
D008585
- **Condition**  
Streptococcal Infections

**Highest recorded phase**  
2

**Condition identifier**  
EFO:1001476

**Subject identifier**  
D013290
- **Condition**  
Alzheimer Disease

**Highest recorded phase**  
1

**Condition identifier**  
MONDO:0004975

**Subject identifier**  
D000544
- **Condition**  
Multiple Sclerosis

**Highest recorded phase**  
3

**Condition identifier**  
MONDO:0005301

**Subject identifier**  
D009103

### Open Targets indications (6)

- **Condition identifier**  
EFO\_0000650

**Highest recorded phase**  
3
- **Condition identifier**  
EFO\_0000772

**Highest recorded phase**  
1
- **Condition identifier**  
EFO\_0005593

**Highest recorded phase**  
3
- **Condition identifier**  
EFO\_1001476

**Highest recorded phase**  
2
- **Condition identifier**  
MONDO\_0004975
- **Condition identifier**  
MONDO\_0005077

### Reported adverse events (6)

- **Event**  
congenital arterial malformation

**Reports**  
2

**Reporting signal score**

14.1932
- **Event**  
cytogenetic abnormality

**Reports**  
2

**Reporting signal score**

11.0925
- **Event**  
gestational diabetes

**Reports**  
3

**Reporting signal score**

13.9675
- **Event**  
postpartum haemorrhage

**Reports**  
2

**Reporting signal score**

10.8563
- **Event**  
ventricular septal defect

**Reports**  
3

**Reporting signal score**

12.9691
- **Event**  
viith nerve paralysis

**Reports**  
3

**Reporting signal score**

14.3269

### Trial references (11)

- NCT00004799  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00004799)
- NCT00004800  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00004800)
- NCT04793620  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04793620)
- NCT05116241  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05116241)
- NCT00329901  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00329901)
- NCT00488826  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT00488826)
- NCT01262924  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01262924)
- NCT04766086  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04766086)
- NCT05028634  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05028634)
- NCT05183516  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05183516)
- NCT05613205  
Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05613205)

## Chemical properties

**Prodrug**

No

**Chirality**

Single enantiomer

**Inorganic**

No

**Natural product**

No

## Related records

### Trials (36)

- A Combined Tdap Vaccine Used As A Booster Compared To Licensed Td Vaccine
- A Phase 4, Placebo-Controlled, Randomized Study to Evaluate the Immunogenicity and Safety of HPV and Tdap When Administered With MenACWY in Adolescents
- A Post-marketing, Observational, Retrospective Study to Assess the Safety of RefortrixTM (Tdap) When Administered During Pregnancy in a Maternal Immunization Program in Brazil.
- A Study to Evaluate Safety, Reactogenicity, and Immune Response of GVGH iNTS-TCV Vaccine Against Invasive Nontyphoidal Salmonella and Typhoid Fever
- A Trial Evaluating a 7-valent Pneumococcal Conjugate Vaccine Given With Diphtheria, Tetanus, and Acellular Pertussis Vaccine (DTaP) in Healthy Japanese Infants.
- Booster Study of Combined Diphtheria-tetanus-acellular Pertussis Vaccine in Healthy Adults
- Bordetella Pertussis Colonisation Challenge Study
- Comparison of Safety and Immunogenicity of Pediacel™ and Infanrix™ IPV+Hib (Penta) Given in a 3 Dose Schedule in Infants
- Establishing a Controlled Human Infection Model of Bordetella Pertussis
- Establishing a Controlled Human Infection Model of Pertactin-deficient Bordetella Pertussis
- Immunogenicity and Safety of ADACEL™ as Fifth Dose in Taiwan
- [Immunogenicity and Safety of BPZE1 Intranasal Pertussis Vaccine in Healthy School-age Children](https://trialight.com/data/trial/immunogenicity-and-safety-of-bpze1-intranasal-pertussis-97009868-a889-40f1-a412-79cfd58fed5a.md)
- Immunogenicity and Safety of the Concomitant Administration of a Tdap Vaccine and Meningococcal ACWY Conjugate Vaccine in Healthy Subjects Aged 11-25 Years
- Immunogenicity of Adacel® and BOOSTRIX® Vaccines in Adolescents
- Longitudinal Tracking of Bone Marrow Plasma Cell Responses to Licensed Human Vaccines
- Periscope Phase C Bordetella Pertussis Human Challenge Study With Delayed Antibiotic Therapy for 6 Weeks
- Pertussis (Tdap) Vaccination in Pregnancy
- Pertussis Acellular Vaccine Adjuvanted With TQL1055
- Phase I/II Clinical Trial of Diphtheria-Tetanus-Pertussis (Reduced Dose) Vaccine
- Phase III Randomized, Double-Blind, Placebo-Controlled Study of Acellular and Whole-Cell Pertussis Vaccines

### In development for (9)

- [Alzheimer disease](https://trialight.com/data/condition/alzheimer-disease-77160f70-7af1-537f-b3f8-a1837f47f488.md) Phase 1
- [Meningococcal meningitis](https://trialight.com/data/condition/meningococcal-meningitis-986c81ca-25d6-5c71-bad2-6d638b296341.md) Phase 3
- [Multiple sclerosis](https://trialight.com/data/condition/multiple-sclerosis-62806c95-fe1b-529e-bd16-95cb92d15375.md) Phase 3
- [Pertussis](https://trialight.com/data/condition/pertussis-810232d3-8d41-590a-8f38-1061f23d3a9f.md) Phase 3
- [Pneumococcal infection](https://trialight.com/data/condition/pneumococcal-infection-b3a7fc66-25ac-57f8-8fb4-073403fe8b1b.md) Phase 1
- [Relapsing-remitting multiple sclerosis](https://trialight.com/data/condition/relapsing-remitting-multiple-sclerosis-dbe6fc02-bfff-56b7-8299-64be5abdf415.md) Phase 3
- [Streptococcal infection](https://trialight.com/data/condition/streptococcal-infection-a0e9c8b4-cd46-573c-81e7-605778524e6c.md) Phase 2
- [Tetanus](https://trialight.com/data/condition/tetanus-a589c209-81c5-56e6-8a55-6d96fedb2c61.md) Phase 3
- [Typhoid fever](https://trialight.com/data/condition/typhoid-fever-ea47c7a2-6a13-5caf-864c-444d3ac1522a.md) Phase 1

---

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