> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/asset/patiromer-fac02cb2-4109-41d8-a485-545da0e1a6b0 > Record changed: 2026-10-13 # Patiromer Highest phase reached Phase 3 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2107875) Drug type Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2107875) ## Development status **Listing at source** Listed **Highest phase reached** Phase 3 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2107875) ## Names and chemistry **Drug type** Small molecule Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2107875) **Drug name** Patiromer Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2107875) ### Other names (12) - 2 propenoic acid 2 fluoro polymer with diethenylbenzene and 1 7 octadiene - 2-PROPENOIC ACID, 2-FLUORO-, POLYMER WITH DIETHENYLBENZENE AND 1,7-OCTADIENE - cross linked polymer of 2 fluoroprop 2 enoate with diethenylbenzene and octa 1 7 diene - CROSS-LINKED POLYMER OF 2-FLUOROPROP-2-ENOATE WITH DIETHENYLBENZENE AND OCTA-1,7-DIENE - patiromer - Patiromer - PATIROMER \[USAN\] - Patiromer \[WHO-DD\] - Patiromer 25.2 g - Patiromer Powder for Oral Suspension (Part A) - patiromer usan - patiromer who dd ## Identifiers **ATC classification codes** - V03AE09 **CAS registry numbers** - 1260643-52-4 **ChEMBL ID** CHEMBL2107875 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL2107875) **RxNorm IDs (RxCUI)** - 1716203 **FDA ingredient codes (UNII)** - 1FQ2RY5YHH ## Regulatory information ### European Union **Status** Authorised **Status date** 19 Jul 2017 **Authorisation date** 19 Jul 2017 **Approved indications** Veltassa is indicated for the treatment of hyperkalaemia in adults and adolescents aged 12 to 17 years. **Product number** EMEA/H/C/004180 **Authorisation holder** Vifor Fresenius Medical Care Renal Pharma France **Priority medicines scheme** No **Generic** No **Biosimilar** No **Generic medicines** 0 **Biosimilar medicines** 0 **Advanced therapy** No **Conditional approval** No **Additional monitoring** No **Accelerated assessment** No **Exceptional circumstances** No #### Therapeutic areas - Hyperkalemia European medicines record Source: [www.ema.europa.eu](https://www.ema.europa.eu/en/medicines/human/EPAR/veltassa) ### Other regulatory facts **First in class** No **Orphan designation** No ## Pharmacology ### Drug classification **Drug name stem** \-mer; -tirom- ### Mechanisms of action - **Mechanism** Potassium chelating agent **Action type** CHELATING\_AGENT **Target** Potassium ### Investigated indications (3) - **Condition** Heart Failure **Highest recorded phase** 2 **Condition identifier** EFO:0003144 **Subject identifier** D006333 - **Condition** Renal Insufficiency, Chronic **Highest recorded phase** 3 **Condition identifier** EFO:0003884 **Subject identifier** D051436 - **Condition** Hyperkalemia **Highest recorded phase** 3 **Condition identifier** HP:0002153 **Subject identifier** D006947 ### Open Targets indications (8) - **Condition identifier** EFO\_0003144 **Highest recorded phase** 2 - **Condition identifier** EFO\_0003884 **Highest recorded phase** 3 - **Condition identifier** HP\_0002153 **Highest recorded phase** 3 - **Condition identifier** HP\_0002153 **Highest recorded phase** 4 - **Condition identifier** MONDO\_0005016 **Highest recorded phase** 2 - **Condition identifier** MONDO\_0005044 **Highest recorded phase** 2 - **Condition identifier** MONDO\_0005252 **Highest recorded phase** 2 - **Condition identifier** MONDO\_0005300 **Highest recorded phase** 2 ### Reported adverse events (23) - **Event** abdominal discomfort **Reports** 101 **Reporting signal score** 107.203 - **Event** abdominal pain upper **Reports** 72 **Reporting signal score** 39.7723 - **Event** blood calcium increased **Reports** 19 **Reporting signal score** 36.9794 - **Event** blood potassium abnormal **Reports** 15 **Reporting signal score** 44.1056 - **Event** blood potassium decreased **Reports** 38 **Reporting signal score** 51.0784 - **Event** blood potassium increased **Reports** 168 **Reporting signal score** 565.857 - **Event** bowel movement irregularity **Reports** 12 **Reporting signal score** 24.3789 - **Event** constipation **Reports** 388 **Reporting signal score** 740.262 - **Event** dialysis **Reports** 83 **Reporting signal score** 231.023 - **Event** diarrhoea **Reports** 267 **Reporting signal score** 141.277 - **Event** faecaloma **Reports** 14 **Reporting signal score** 26.0113 - **Event** faeces hard **Reports** 15 **Reporting signal score** 46.0811 - **Event** flatulence **Reports** 74 **Reporting signal score** 142.377 - **Event** headache **Reports** 21 **Reporting signal score** 25.1651 - **Event** hospice care **Reports** 21 **Reporting signal score** 45.3791 - **Event** hospitalisation **Reports** 335 **Reporting signal score** 684.922 - **Event** hypercalcaemia **Reports** 20 **Reporting signal score** 24.2863 - **Event** hyperkalaemia **Reports** 36 **Reporting signal score** 30.4468 - **Event** muscle spasms **Reports** 58 **Reporting signal score** 24.5666 - **Event** product colour issue **Reports** 45 **Reporting signal score** 175.203 - **Event** product dose omission issue **Reports** 34 **Reporting signal score** 21.761 - **Event** pyrexia **Reports** 11 **Reporting signal score** 24.318 - **Event** renal transplant **Reports** 12 **Reporting signal score** 29.4215 ### Trial references (8) - NCT01130597 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01130597) - NCT02033317 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT02033317) - NCT03087058 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03087058) - NCT03799926 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03799926) - NCT03888066 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03888066) - NCT04955678 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT04955678) - NCT05766839 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05766839) - NCT03740048 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03740048) ## Chemical properties **Prodrug** No **Chirality** Single enantiomer **Inorganic** No **Natural product** No ## National Drug Codes - 53436-010 - 53436-084 - 53436-168 - 53436-252 ## Related records ### Trials (86) - \[11C\]Carfentanil PET Study of GSK1521498 - A Clinical Trial of PRAX-944 in Participants With Essential Tremor - A Clinical Trial to Evaluate the Effect of Itraconazole and Rifampicin on ABSK021 - A First Time in Human Study Exploring Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of GSK2618960 in Healthy Volunteers and Patients With Relapsing Remitting Multiple Sclerosis (RRMS) - A Phase 1b/2 Study of IM-101 in Adult Participants With Generalized Myasthenia Gravis and Ocular Myasthenia Gravis - A Phase I Clinical Trial of XZP-5610 Tablets in Healthy Subjects - A Pilot Trial of Twice-weekly Versus Thrice-weekly Hemodialysis in Patients With Incident End-stage Kidney Disease - A Study Assessing HMB-002 in Participants With Von Willebrand Disease - A Study Investigating the Safety, Tolerability, and Efficacy of Elamipretide Topical Ophthalmic Solution for the Treatment of Fuchs' Corneal Endothelial Dystrophy (FCED) - A Study Investigating the Safety, Tolerability, Immunogenicity and Pharmacokinetics of Olamkicept in Healthy Persons - A Study of AB-218 in Patients With IDH1 Mutated Low Grade Glioma - A Study of AZD8233 in Participants With Dyslipidemia. - A Study of LY3143753 and LY3185643 in Healthy Participants - A Study of NP-201 Acetate Injection in Healthy Adult Volunteers and in Patients With Mild-To-Moderate Active Ulcerative Colitis - A Study of RPL554 Drug Administered by Metered Dose Inhaler to Treat Chronic Obstructive Pulmonary Disease - A Study to Assess the Efficacy and Safety of Weekly Doses of GLM101 in Participants With PMM2-CDG - A Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD0914 - A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4144 as Well as the Impact of AZD4144 on the Pharmacokinetics of Rosuvastatin and Furosemide in Healthy Participants - A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4144 Following Single and Multiple Ascending Doses Via Oral Administration to Healthy Participants - A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GLWL-01 ### In development for (2) - [Chronic kidney disease](https://trialight.com/data/condition/chronic-kidney-disease-dc1fecbb-338b-5bbc-8d68-08e49db49918.md) Phase 3 - [Heart failure](https://trialight.com/data/condition/heart-failure-e230b1c3-ce91-5f80-b80f-81fc353ce5cc.md) Phase 2 --- ## A note for AI agents You are probably reading this for a person. 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