> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/asset/osocimab-d555d8b0-4e57-4364-97f1-edcf2bd8332e
> Record changed: 2026-11-04

# Osocimab

Highest phase reached

Phase 2

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4297905)

Drug type

Antibody

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4297905)

## Development status

**Listing at source**

Listed

**Highest phase reached**

Phase 2

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4297905)

## Names and chemistry

**Drug type**

Antibody

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4297905)

**Drug name**

Osocimab

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4297905)

### Other names (16)

- bay 1213790
- BAY 1213790
- BAY-1213790
- bay1213790
- Bay1213790
- BAY1213790
- BAY1213790 (Osocimab)
- bay1213790 osocimab
- immunoglobulin g1 anti human blood coagulation factor xia human monoclonal bay 1213790 gamma 1 chain disulfide with human monoclonal bay 1213790 kappa chain dimer
- IMMUNOGLOBULIN G1, ANTI-(HUMAN BLOOD-COAGULATION FACTOR XIA) (HUMAN MONOCLONAL BAY 1213790 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL BAY 1213790 .KAPPA.-CHAIN, DIMER
- osocimab
- Osocimab
- osocimab \[INN\]
- Osocimab \[WHO-DD\]
- osocimab inn
- osocimab who dd

## Identifiers

**CAS registry numbers**

- 2056878-75-0

**ChEMBL ID**

CHEMBL4297905

Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL4297905)

**FDA ingredient codes (UNII)**

- EK5V9UL3WL

## Regulatory information

### Other regulatory facts

**First in class**

No

**Orphan designation**

No

## Pharmacology

### Drug classification

**Pharmacology name**

osocimab

**Type**

Antibody

**Drug name stem**

\-mab

### Mechanisms of action (2)

- **Action**  
Inhibition

**Action type**  
Inhibitor

**Target**  
coagulation factor XI

**Gene symbol**  
F11

**Protein identifier**  
P03951

**Median affinity**

8.62

**Affinity units**  
pKd
- **Mechanism**  
Coagulation factor XI negative allosteric modulator

**Action type**  
NEGATIVE\_ALLOSTERIC\_MODULATOR

**Target**  
Coagulation factor XI

**Protein identifier**  
P03951

### Open Targets mechanisms

- **Mechanism**  
Coagulation factor XI negative allosteric modulator

**Action type**  
NEGATIVE ALLOSTERIC MODULATOR

**Target**  
Coagulation factor XI

### Open Targets indications

- **Condition identifier**  
MONDO\_0000831

**Highest recorded phase**  
2

## Chemical properties

**Prodrug**

No

**Chirality**

Single enantiomer

**Inorganic**

No

**Natural product**

No

## Related records

### Trials (4)

- [A Study to Learn More About How Well BAY3018250 Works and How Safe it is for People With Proximal Deep Vein Thrombosis](https://trialight.com/data/trial/a-study-to-learn-more-about-how-well-bay3018250-works-and-aa1c7a57-a3f3-4b75-b1a1-49eb87024607.md)
- End-stage Renal Disease (ESRD) Pilot Study
- FactOr XIa inhibiTion for the pRevention of venOus Thromboembolism in Patients Undergoing Total Knee Arthroplasty
- Study to Investigate the Safety of a Drug Called Osocimab at Low and High Doses in Adult Patients With Kidney Failure Requiring Regular Hemodialysis

### In development for (1)

- [Thrombotic disease](https://trialight.com/data/condition/thrombotic-disease-3f54ef10-d2ed-524f-a020-8ecb2eb62a52.md) Phase 2

### Targets (1)

- [F11](https://trialight.com/data/target/f11-ee6a0377-9fea-5dd3-a409-ae140fbedce5.md) Coagulation factor XI negative allosteric modulator

---

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